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Retroperitoneal fibrosis and chronic periaortitis: a new hypothesis.

Abstract：

:The etiology of retroperitoneal fibrosis (Ormond's disease) has still not been clarified. A new hypothesis postulates chronic fibrosing periaortitis. Atherosclerosis of the abdominal aorta and plaque rupture lead to the liberation of oxidized lipoproteins through the adventitia into the periaortic fatty tissue. This results in a chronic inflammatory process. In support of the periaortitis hypothesis is our finding that 9 of 14 consecutively studied patients with retroperitoneal fibrosis had either proven atherosclerosis of the abdominal aorta or a high probability of this in view of multiple vascular risk factors. No patients had received previous methysergide medication.

journal_name

Eur Urol

journal_title

European urology

authors

Martina FB,Nüech R,Gasser TC

doi

10.1159/000474632

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

371-4

issue

3

eissn

0302-2838

issn

1873-7560

journal_volume

23

pub_type

杂志文章

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