F-actin, tubulin and spectrin in the organ of Corti: comparative distribution in different cell types and mammalian species.

abstract：:Thresholds to sinusoidal and biphasic pulsatile electrical stimuli were measured in two patients with electrodes positioned on the cochlear nucleus. The threshold functions differ from those observed in patients with scala tympani electrodes, primarily at low sinusoidal frequencies and long pulse widths. This differen...

journal_title：Hearing research

authors： Shannon RV

更新日期：1989-06-15 00:00:00

abstract：:The waveforms of the auditory evoked magnetic field in normal-hearing individuals and patients suffering from tinnitus are distinctly different. In tinnitus patients, the magnetic wave M200 (corresponding to the electric wave P200, or P2) is delayed and only poorly developed or even completely missing, while the ampli...

journal_title：Hearing research

authors： Hoke M,Feldmann H,Pantev C,Lütkenhöner B,Lehnertz K

更新日期：1989-02-01 00:00:00

abstract：:A model for cochlear mechanics is proposed to take account of its two systems, one passive and one active. The classical passive system stimulates the inner hair cells directly at levels above about 40 dB SL. At intensities below about 60 dB an active process, the 'cochlear amplifier' (CA), somehow provides additional...

journal_title：Hearing research

authors： Davis H

更新日期：1983-01-01 00:00:00

abstract：:Nitric oxide (NO) is a messenger molecule that mediates several physiological functions and pathological processes. Sodium nitroprusside (SNP), a potent vasodilator, when given clinically as an anti-hypertension agent, exerts its function by releasing NO. It was reported recently that SNP causes a loss of auditory ner...

journal_title：Hearing research

authors： Kong WJ,Ren T,Nuttall AL

更新日期：1996-09-15 00:00:00

abstract：:The suppression tuning properties of the oto-acoustic distortion product emission, 2f1-f2 have been measured in the ear canal of gerbil and man. The results show the acoustic response to be suppressible in a similar, frequency-dependent manner in both species. Frequencies near to those of the stimulating tones are mos...

journal_title：Hearing research

authors： Brown AM,Kemp DT

更新日期：1984-01-01 00:00:00

abstract：:Glutamate has been implicated in signal transmission between inner hair cells and afferent fibers of the organ of Corti. The inner hair cells are enriched in glutamate and the postsynaptic membranes express AMPA glutamate receptors. However, it is not known whether inner hair cells contain a mechanism for glutamate re...

journal_title：Hearing research

authors： Oguchi T,Suzuki N,Hashimoto S,Chaudhry GA,Chaudhry FA,Usami S,Ottersen OP

更新日期：2012-10-01 00:00:00

abstract：:Normal-hearing listeners can perceptually segregate concurrent sound sources, but listeners with significant hearing loss or who wear a cochlear implant (CI) lag behind in this ability. Perceptual grouping mechanisms are essential to segregate concurrent sound sources and affect comodulation masking release (CMR). Thu...

journal_title：Hearing research

authors： Zirn S,Hempel JM,Schuster M,Hemmert W

更新日期：2013-02-01 00:00:00

abstract：:We studied the 2IFC detectability of a 500 Hz tone masked by computer-generated maskers under the N0SII interaural condition, and under two masker conditions. In the first masker condition the maskers in the two intervals of a trial were independent of each other, and in the second masker condition the maskers were id...

journal_title：Hearing research

authors： Siegel RA,Colburn HS

更新日期：1983-08-01 00:00:00

abstract：:The highly variable benefit of hearing devices is a serious challenge in auditory rehabilitation. Various factors contribute to this phenomenon such as the diversity in ear defects, the different extent of auditory nerve hypoplasia, the age of intervention, and cognitive abilities. Recent analyses indicate that, in ad...

journal_title：Hearing research

authors： Willaredt MA,Ebbers L,Nothwang HG

更新日期：2014-06-01 00:00:00

abstract：:Carbohydrate distribution in the fresh utricular macula of the guinea pig was analysed using lectins such as Concanavalin A (ConA), Dolichos biflorus agglutinin (DBA), peanut agglutinin (PNA), soybean agglutinin (SBA), Ulex europeus agglutinin (UEA-1) and wheat germ agglutinin (WGA) by means of confocal laser scanning...

journal_title：Hearing research

authors： Suzuki H,Katori Y,Ikeda K,Takasaka T

更新日期：1995-07-01 00:00:00

abstract：:Georg von Békésy designed the instruments needed for his research. He also created physical models of the cochlea allowing him to manipulate the parameters (such as volume elasticity) that could be involved in controlling traveling waves. This review is about the specific devices that he used to study the motion of th...

journal_title：Hearing research

authors： Nuttall AL,Fridberger A

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:Molecular analysis using archival human inner ear specimens is challenging because of the anatomical complexity, long-term fixation, and decalcification. However, this method may provide great benefit for elucidation of otological diseases. Here, we extracted mRNA for RT-PCR from tissues dissected from archiv...

journal_title：Hearing research

authors： Kimura Y,Kubo S,Koda H,Shigemoto K,Sawabe M,Kitamura K

更新日期：2013-08-01 00:00:00

abstract：:For the elevation and front-versus-back hemifield of a sound source to be accurately determined, the sound must contain a broad range of frequencies. Experiment 1 of this study examined the spectral integration time of the auditory localisation system by measuring the accuracy with which frequency-modulated (FM) tones...

journal_title：Hearing research

authors： Martin RL,McAnally KI

更新日期：2008-04-01 00:00:00

abstract：:The lipophilic dye, DiI, was placed into the macula lagena of paraformaldehyde-fixed embryonic chicks. Retrogradely labeled cells were found bilaterally in the pontine reticular formation (RF) between the dorsal facial nucleus and the abducens nerve root. This location is similar to that of the dorsomedial group of ef...

journal_title：Hearing research

authors： Code RA

更新日期：1995-01-01 00:00:00

abstract：:A model was developed to simulate acoustically the effects of excitation spread in cochlear implants (CI). Based on neurophysiologic data, the proposed model simulates the electrical-current decay rate associated with broad and narrow types of excitation, such as those produced by monopolar and bipolar electrode confi...

journal_title：Hearing research

authors： Bingabr M,Espinoza-Varas B,Loizou PC

更新日期：2008-07-01 00:00:00

abstract：:It is known that adrenocorticotrophic hormone (ACTH)-derived peptides, the so-called melanocortins, can reduce cisplatin-induced neurotoxicity. Recently, our group has found that cisplatin-induced ototoxicity can also be reduced or prevented by treatment with the synthetic melanocortin-like peptide, ORG 2766 (Hamers e...

journal_title：Hearing research

authors： Heijmen PS,Klis SF,De Groot JC,Smoorenburg GF

更新日期：1999-02-01 00:00:00

abstract：:A number of studies have shown that the ear can be protected from sound over-exposure, either by activating the cochlear efferent system, or by sound 'conditioning' in which the role of the efferent system is less certain. To study more definitively the molecular basis of deliberately induced cochlear protection from ...

journal_title：Hearing research

authors： Vázquez AE,Luebke AE,Martin GK,Lonsbury-Martin BL

更新日期：2001-06-01 00:00:00

abstract：:Cochlear Implant (CI) sound coding strategies based on simultaneous stimulation lead to an increased loudness percept when compared to sequential stimulation using the same current levels. This is due to loudness summation as a result of channel interactions. Studying the loudness perception evoked by dual-channels co...

journal_title：Hearing research

authors： Langner F,McKay CM,Büchner A,Nogueira W

更新日期：2020-12-01 00:00:00

abstract：:Two-tone stimuli have traditionally been used to reveal regions of inhibition in auditory spectral receptive fields, particularly for neurons with low spontaneous rates. These techniques reveal how different frequencies excite or suppress the response to an excitatory frequency of a cell, but have often been assessed ...

journal_title：Hearing research

authors： Brimijoin WO,O'Neill WE

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVES:Existing evidence suggests a strong relationship between tinnitus and emotion. The objective of this study was to examine the effects of short-term emotional changes along valence and arousal dimensions on tinnitus outcomes. Emotional stimuli were presented in two different modalities: auditory and visual. T...

journal_title：Hearing research

authors： Durai M,O'Keeffe MG,Searchfield GD

更新日期：2017-03-01 00:00:00

abstract：:Human subjects performed in several behavioral conditions requiring, or not requiring, selective attention to visual stimuli. Specifically, the attentional task was to recognize strings of digits that had been presented visually. A nonlinear version of the stimulus-frequency otoacoustic emission (SFOAE), called the nS...

journal_title：Hearing research

authors： Walsh KP,Pasanen EG,McFadden D

更新日期：2014-06-01 00:00:00

abstract：:Several studies have demonstrated that treatment with intracochlear chronic electrical stimulation (CES) protects spiral ganglion cells (SGCs) from degeneration in deafened animals. Other studies could not confirm this effect of CES. The present study examined whether CES in a mode as presented in cochlear implant use...

journal_title：Hearing research

authors： Agterberg MJ,Versnel H,de Groot JC,van den Broek M,Klis SF

更新日期：2010-10-01 00:00:00

abstract：:Peripheral auditory adaptation has been studied extensively in animal models, and multiple exponential components have been identified. This study explores the feasibility of estimating these component processes for human listeners with a peripheral model of adaptation. The processes were estimated from off-frequency ...

journal_title：Hearing research

authors： Formby C,Rutledge JC,Sherlock LP

更新日期：2002-02-01 00:00:00

abstract：:Immunocytochemical methods were used to examine cryosections of the embryonic and neonatal chicken cochlea in order to study the histological distribution of the Na+,K+-ATPase molecule during maturation. In complementary studies the Na+,K+-ATPase capacity of microdissected freeze-dried substructures of the cochlea was...

journal_title：Hearing research

authors： Schneider ME,Cotanche DA,Fambrough DM,Saunders JC,Matschinsky FM

更新日期：1987-11-01 00:00:00

abstract：:The responses to two identical, consecutive pure tone stimuli with varying inter-stimulus intervals (delta ts) were measured for 89 neurons in the cochlear nucleus of the anaesthetised guinea pig. We observed two main effects; either a decrease (suppression) or an increase (facilitation) in response to the second tone...

journal_title：Hearing research

authors： Bleeck S,Sayles M,Ingham NJ,Winter IM

更新日期：2006-02-01 00:00:00

abstract：:The possible presence of different types of delayed rectifier K+ current (I(K)) was studied in vestibular hair cells of frog semicircular canals. Experiments were performed in thin slice preparations of the whole crista ampullaris and recordings were made using the whole-cell patch-clamp technique. We found that an ap...

journal_title：Hearing research

authors： Marcotti W,Russo G,Prigioni I

更新日期：1999-09-01 00:00:00

abstract：:Differences between inner and outer hair cells in the cellular content of precipitable calcium were detected using a potassium pyroantimonate precipitation method and the electron spectroscopic imaging (ESI-) technique. The cytoplasm of the inner hair cells was scattered with a high number of calcium precipitates in a...

journal_title：Hearing research

authors： Maurer J,Heinrich UR,Mann W

更新日期：1994-01-01 00:00:00

abstract：:The rather shallow growth of click-evoked otoacoustic emissions (CEOAE) with click intensity, namely <1 dB/dB, distinguishes genuine CEOAEs from stimulus artifacts, thereby providing the rationale for the popular 'derived nonlinear recording' method. However, other CEOAE nonlinearities regarding phase or envelope depe...

journal_title：Hearing research

authors： Carvalho S,Büki B,Bonfils P,Avan P

更新日期：2003-01-01 00:00:00

abstract：:The peripheral auditory sense organ, the cochlea, receives innervation from lateral and medial olivocochlear neurons in the brainstem. These neurons are able to modulate cochlear neural output. Anatomical studies have shown that one of the neurotransmitters which is present in varicosities surrounding the olivocochlea...

journal_title：Hearing research

authors： Mulders WH,Robertson D

更新日期：2005-06-01 00:00:00

abstract：:In order to investigate the localization and the type(s) of excitatory amino acid receptors in the frog vestibular system, the exogenous amino acid agonists Quisqualic acid, Kainic acid and N-methyl-D-aspartic acid were tested on the sensory organ of semicircular canals. Intracellular recordings of the resting dischar...

journal_title：Hearing research

authors： Prigioni I,Russo G,Valli P,Masetto S

更新日期：1990-07-01 00:00:00