Spectral integration time of the auditory localisation system.

abstract：:Tone-burst-evoked compound action potentials (CAP) from the guinea pig round window (RW) are altered by DC current injection through the RW. The CAP waveform consists of a series of interleaved negative and positive peaks (N(1), P(1), N(2), P(2) etc.) of decreasing amplitude. During positive DC current injection (arou...

journal_title：Hearing research

authors： Brown DJ,McMahon CM,Patuzzi RB

更新日期：2004-04-01 00:00:00

abstract：:Spatial hearing skills are essential for children as they grow, learn and play. These skills provide critical cues for determining the locations of sources in the environment, and enable segregation of important sounds, such as speech, from background maskers or interferers. Spatial hearing depends on availability of ...

journal_title：Hearing research

authors： Litovsky RY,Gordon K

更新日期：2016-08-01 00:00:00

abstract：:Stiffness of hair bundles on cochlear hair cells was measured in turns 2, 3 and 4 of isolated preparations of the guinea-pig organ of Corti maintained in tissue culture medium. Defined as the force required to produce a linear 1.0 micron deflection of the hair-bundle tip, stiffness is greater for deflection in the exc...

journal_title：Hearing research

authors： Strelioff D,Flock A

更新日期：1984-07-01 00:00:00

abstract：:This paper reviews some of what is known about ion transport through the cells of the mammalian stria vascularis, and discusses how the endolymph and endocochlear potential in scala media are produced by the stria's main cell types. It discusses the role of each cells' ion transport proteins from an engineering perspe...

journal_title：Hearing research

authors： Patuzzi R

更新日期：2011-07-01 00:00:00

abstract：:Certain hair cells of fish exhibit strong immunoreactivity to an S-100 antibody. By their spatial locations in the utricle and saccule, these hair cells appear to possess a relatively short kinocilium and a roughly ovoid cell shape. In the utricle, these cells are predominantly located in the striola. In the saccule, ...

journal_title：Hearing research

authors： Saidel WM,Presson JC,Chang JS

更新日期：1990-08-01 00:00:00

abstract：:Severe damage to the organ of Corti leads to degeneration of the spiral ganglion cells (SGCs) which form the auditory nerve. This degeneration starts at the level of synaptic connection of the peripheral processes (PPs) of SGCs with the cochlear hair cells. It is generally thought that from this point SGC degeneration...

journal_title：Hearing research

authors： Ramekers D,Klis SFL,Versnel H

更新日期：2020-05-01 00:00:00

abstract：:Recently, ocular vestibular evoked myogenic potentials (oVEMPs) have been described and added to the neuro-otologic test battery as a new measure for the vestibulo-ocular reflex. oVEMPs represent extraocular muscle activity in response to otolith stimulation e.g. by air-conducted sound or bone-conducted vibration. In ...

journal_title：Hearing research

authors： Kantner C,Gürkov R

更新日期：2012-12-01 00:00:00

abstract：:Both sound exposure and gentamicin treatment cause damage to sensory hair cells in the peripheral chick auditory organ, the basilar papilla. This induces a regeneration response which replaces hair cells and restores auditory function. Since functional recovery requires the re-establishment of connections between rege...

journal_title：Hearing research

authors： Ofsie MS,Hennig AK,Messana EP,Cotanche DA

更新日期：1997-11-01 00:00:00

abstract：:Light microscopy and immunohistochemical analyses of a freshly prepared human cochlea, removed at meningioma skull base surgery, were performed with particular emphasis on synaptophysin (SY) reactivity. Synaptophysin, a 38-kDa glycoprotein, is one of the most abundant integral membrane proteins of small presynaptic ve...

journal_title：Hearing research

authors： Khalifa SA,Friberg U,Illing RB,Rask-Andersen H

更新日期：2003-11-01 00:00:00

abstract：:We have studied properties of a nonlinear one-dimensional model for motion of the basilar membrane. The model is able to reproduce a variety of physiological and psychophysical effects, and in some instances predictions of the model have been subssequently confirmed. We regard the agreement between model and nature as...

journal_title：Hearing research

authors： Hall JL

更新日期：1980-06-01 00:00:00

abstract：:Adenosine plays a major cytoprotective role during ischemia and conditions of oxidative stress. Previous studies in our laboratory indicate that oxidative stress induces expression of the A1 adenosine receptor (A1AR) via activation of nuclear factor (NF)-kappaB. In this study, we tested whether noise exposure could in...

journal_title：Hearing research

authors： Ramkumar V,Whitworth CA,Pingle SC,Hughes LF,Rybak LP

更新日期：2004-02-01 00:00:00

abstract：:Exposure of the vestibulo-cochlear anastomosis in the cat allows single-unit recording of afferent fibers originating from inner hair cells and olivocochlear efferent fibers to the outer hair cells. Comparison of data obtained from individual animals show similarities in absolute threshold and dynamic range between th...

journal_title：Hearing research

authors： Liberman MC

更新日期：1988-07-15 00:00:00

abstract：:Sensorineural hearing loss, which is often caused by degeneration of hair cells in the auditory epithelium, is permanent because lost hair cells are not replaced. Several conceptual approaches can be used to place new hair cells in the auditory epithelium. One possibility is to enhance proliferation of non-sensory cel...

journal_title：Hearing research

authors： Minoda R,Izumikawa M,Kawamoto K,Zhang H,Raphael Y

更新日期：2007-10-01 00:00:00

abstract：:Expression of mineralocorticoid type I receptor (MR) gene in the rat cochlea was determined using molecular biological techniques. We synthesized complementary DNA (cDNA) from rat cochlear total RNA and then amplified MR cDNA fragments by polymerase chain reaction (PCR). The amplified cDNA fragments were subcloned int...

journal_title：Hearing research

authors： Furuta H,Mori N,Sato C,Hoshikawa H,Sakai S,Iwakura S,Doi K

更新日期：1994-08-01 00:00:00

abstract：:Spectral analysis of electrical noise recorded from the round window (RW) of the cochlea is referred to as the ensemble spontaneous activity (ESA) of the cochlear nerve. The ESA is considered to represent the summed spontaneous activity of single fibers of the auditory nerve and changes in the spectral characteristics...

journal_title：Hearing research

authors： Searchfield GD,Muñoz DJ,Thorne PR

更新日期：2004-06-01 00:00:00

abstract：:To create experimental lesions localized to the low frequency region of the organ of Corti, a cryoprobe was applied to the apical area of 37 cochleas from 26 adult chinchillas. Twenty cochleas were exposed to single applications of a cryoprobe for 2.5, 3.0 and 3.5 min; 17 cochleas were exposed to two applications of 1...

journal_title：Hearing research

authors： Brown JN,Nuttall AL

更新日期：1987-01-01 00:00:00

abstract：:The induction of the heat shock protein, HSP72, was studied in the cochlea of guinea pigs and rats subjected to a hyperthermic stress. Analyses were done by immunoblotting and immunocytochemistry at 6 and 12 h after heat shock, using a commercially available monoclonal antibody (Amersham), and by in situ hybridization...

journal_title：Hearing research

authors： Dechesne CJ,Kim HN,Nowak TS Jr,Wenthold RJ

更新日期：1992-05-01 00:00:00

abstract：:Otoacoustic emissions (OAEs) differ between the sexes in humans, rhesus and marmoset monkeys, and sheep. OAEs also are different in a number of special populations of humans. Those basic findings are reviewed and discussed in the context of possible prenatal-androgen effects on the auditory system. A parsimonious expl...

journal_title：Hearing research

authors： McFadden D

更新日期：2009-06-01 00:00:00

abstract：:DFNB4 is non-syndromic, autosomal recessive type of hearing loss with an enlarged vestibular aqueduct (EVA) caused by mutations in SLC26A4/pendrin. Although the characteristics of hearing loss are well known in DFNB4, vestibular function remains inconclusive. We evaluated the vestibular function of 31 patients with bi...

journal_title：Hearing research

authors： Jung J,Seo YW,Choi JY,Kim SH

更新日期：2016-05-01 00:00:00

abstract：:A method for long term culture of utricular macula explants is demonstrated to be stable and reproducible over a period of 28 days in vitro (DIV). This culture system for four-day-old rat utricular maculae is potentially suitable for studies of hair cell loss, repair and regeneration processes as they occur in post-na...

journal_title：Hearing research

authors： Werner M,Van De Water TR,Andersson T,Arnoldsson G,Berggren D

更新日期：2012-01-01 00:00:00

abstract：:When using bone vibrator transducers for clinical measurements, the transfer of energy from the bone driver depends on the impedance match between the driver and the load (human mastoid or otherwise) to which the driver will be applied. Current clinical calibration methods are incapable of quantifying this impedance m...

journal_title：Hearing research

authors： Weece R,Allen J

更新日期：2010-05-01 00:00:00

abstract：:The avian basilar papilla (BP) is a likely homolog of the auditory sensory epithelium of the mammalian cochlea, the organ of Corti. During mammalian development Fibroblast growth factor receptor-3 (Fgfr3) is known to regulate the differentiation of auditory mechanosensory hair cells (HCs) and supporting cells (SCs), b...

journal_title：Hearing research

authors： Jacques BE,Dabdoub A,Kelley MW

更新日期：2012-07-01 00:00:00

abstract：:One objective electrophysiological test for deafness involves presenting a brief acoustic stimulus to a subject and measuring the electrical activity evoked in the muscle located just behind the ear (the post-auricular muscle or PAM). Although this electrical response has been known for many years, it has been ignored...

journal_title：Hearing research

authors： O'Beirne GA,Patuzzi RB

更新日期：1999-12-01 00:00:00

abstract：:The avian auditory papilla provides an interesting object on which to study efferent influences, because whereas a significant population of hair cells in birds is not afferently innervated, all hair cells are efferently innervated (Fischer, 1992, 1994a, b). Previous studies in mammals using contralateral sound to sti...

journal_title：Hearing research

authors： Manley GA,Taschenberger G,Oeckinghaus H

更新日期：1999-12-01 00:00:00

abstract：:Recent evidence suggests that the monkey's short-term memory in audition depends on a passively retained sensory trace as opposed to a trace reactivated from long-term memory for use in working memory. Reliance on a passive sensory trace could render memory particularly susceptible to confusion between sounds that are...

journal_title：Hearing research

authors： Scott BH,Mishkin M,Yin P

更新日期：2013-04-01 00:00:00

abstract：:During the simultaneous monaural presentation of two primary tones, distortion products can be measured acoustically in the ear canal (DPOAEs) and electrically as auditory evoked potentials (DPAEPs). The purpose of this investigation was to elucidate the sources of nonlinearity within the human auditory system respons...

journal_title：Hearing research

authors： Bhagat SP,Champlin CA

更新日期：2004-07-01 00:00:00

abstract：:The role of glycine and GABA as inhibitory neurotransmitters in the adult vertebrate nervous system has been well characterized in a variety of model systems, including the auditory, which is particularly well suited for analyzing inhibitory neurotransmission. However, a full understanding of glycinergic and GABAergic...

journal_title：Hearing research

authors： Friauf E,Rust MB,Schulenborg T,Hirtz JJ

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Noise-induced hearing loss (NIHL) is a multifactorial disease, and dysregulation of oxidative stress is universally acknowledged as one crucial pathogenic factor for this disease. Recently studies have found the LncRNA HOTAIR is involved in the alteration of oxidative stress level, cell proliferation, cell c...

journal_title：Hearing research

authors： Wang B,Ding E,Shen H,Wang J,Sun K,Chen S,Han L,Zhang H,Zhu B,Xu M

更新日期：2017-04-01 00:00:00

abstract：:Middle-ear to basilar membrane (BM) velocity transfer functions are reported for seven locations in the hook region of a single cat cochlea. These transfer functions were recorded at high sound pressure levels in a linearized, or passive cochlea, and resemble those reported previously by Wilson and Evans (1983). They ...

journal_title：Hearing research

authors： Cooper NP,Rhode WS

更新日期：1992-11-01 00:00:00

abstract：:The vibration characteristics (amplitude and phase as a function of frequency) of the tympanic membrane in the grass frog were measured using a laser-doppler velocity meter. It was tested to what extent the frog's acoustic system behaves as a pressure gradient receiver. This might clarify how the frog localizes sound....

journal_title：Hearing research

authors： Vlaming MS,Aertsen AM,Epping WJ

更新日期：1984-05-01 00:00:00