Hormone replacement therapy may reduce high serum homocysteine in postmenopausal women.

abstract：BACKGROUND:To date it is not known whether gastric juice vitamin C levels are influenced by Helicobacter pylori CagA(+) strains. The aim of the present study, therefore, was to study the impact of H. pylori CagA status on gastric juice vitamin C levels. MATERIALS AND METHODS:We studied 30 H. pylori(+) patients, and th...

journal_title：European journal of clinical investigation

authors： Rokkas T,Liatsos C,Petridou E,Papatheodorou G,Karameris A,Ladas SD,Raptis SA

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Childhood obesity is associated with premature cardiovascular complications. However, little is known about the effect of a family-based behavioural intervention on the relationship between arterial function, blood pressure and biomarkers in pre-pubertal children with obesity. DESIGN:This was a single centr...

journal_title：European journal of clinical investigation

authors： Maggio ABR,Farpour-Lambert NJ,Aggoun Y,Galan K,Montecucco F,Mach F,Beghetti M

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Epidemiological evidence proposes the direct involvement of the liver enzymes in atrial fibrillation. These relationships are controversial and mechanistically unclear. As part of the British Regional Heart Study, we investigated whether change in liver enzymes over time associates with atrial fibrillation i...

journal_title：European journal of clinical investigation

authors： Schutte R,Whincup PH,Papacosta O,Lennon LT,Macfarlane PW,Wannamethee G

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Portal endotoxaemia has been speculated to be crucially involved in the pathogenesis of chronic hepatic inflammation, which is highly associated with the development of type 2 diabetes mellitus. This study tests whether portal endotoxaemia is a pathogenic link between chronic subacute hepatic inflammation an...

journal_title：European journal of clinical investigation

authors： Hsieh PS,Chan JY,Shyu JF,Chen YT,Loh CH

更新日期：2008-09-01 00:00:00

abstract：:The fate of noradrenaline released from sympathetic endings differs from that of noradrenaline secreted directly into the bloodstream. This has been used to establish a single sample test for the exclusion of phaeochromocytoma in patients with borderline elevation of plasma noradrenaline concentration. This test is ba...

journal_title：European journal of clinical investigation

authors： Brown MJ

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:The investigation of the human follicle fluid proteome has gained much interest in the search of new markers as predictors for in vitro fertilization and intracytoplasmic sperm injection (IVF/ICSI) treatment outcome. Follicular fluid folate, as substrate of one carbon (1-C) metabolism, affects follicular met...

journal_title：European journal of clinical investigation

authors： Twigt JM,Bezstarosti K,Demmers J,Lindemans J,Laven JS,Steegers-Theunissen RP

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Thiopurines (TP) are widely used in the management of inflammatory bowel diseases. Side effects and inefficacy are a major concern as they lead to withdrawal of the drug. MATERIALS AND METHODS:Tools investigating TP metabolism are useful to avoid inadequate cessation of TP therapy. RESULTS:TP metabolism is...

journal_title：European journal of clinical investigation

authors： Dewit O,Starkel P,Roblin X

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Although the incidence of co-existent pulmonary tuberculosis (PTB) and lung cancer in China is increasing, risk factors related to its development are still poorly understood. We aimed to investigate which clinical factors were associated with the odds of co-existent PTB and lung cancer (PTB-lung cancer) cas...

journal_title：European journal of clinical investigation

authors： Zheng L,Yin J,Wang S,Jiang H,Hu P,Kang Z,Lv P,Li W,Cai C

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:The role of the pattern, quantity and site of insulin secretion in the tolerance to a glucose challenge is not fully evaluated in humans because it is difficult to obtain appropriate clinical models. DESIGN:To address this issue, we studied subjects with reduced pancreatic mass (hemipancreatectomized, HEMI)...

journal_title：European journal of clinical investigation

authors： Battezzati A,Zerbi A,Perseghin G,Caumo A,Terruzzi I,Di Carlo V,Luzi L

更新日期：2000-05-01 00:00:00

abstract：:The in situ intraperitoneal volume and the mass transfer area coefficients (MTC) of urea, lactate, creatinine, glucose, kanamycin, inulin, beta 2-microglobulin, albumin and IgG were studied in eight continuous ambulatory peritoneal dialysis (CAPD) patients. All patients were studied during a 4-h dialysis dwell, first ...

journal_title：European journal of clinical investigation

authors： Krediet RT,Zuyderhoudt FM,Boeschoten EW,Arisz L

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Apolipoprotein E epsilon4 allele has been associated with increased risk of coronary heart disease, and is also a major genetic susceptibility locus for Alzheimer's disease. Some studies have shown an association between apoE genotype and ischaemic stroke or outcome following stroke, while other studies have...

journal_title：European journal of clinical investigation

authors： MacLeod MJ,De Lange RP,Breen G,Meiklejohn D,Lemmon H,Clair DS

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Alcohol may have a cardioprotective effect. One possible mechanism is by modifying insulin resistance/secretion. The aims of this study were: (i) to examine the effect of short-term alcohol consumption on the metabolic control of glucose tolerance; (ii) to study the influence of short-term alcohol consumptio...

journal_title：European journal of clinical investigation

authors： Flanagan DE,Pratt E,Murphy J,Vaile JC,Petley GW,Godsland IF,Kerr D

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Studies in different animal models and plasma analyses in humans suggest that members of the interleukin-6 (IL-6) cytokine family may be involved in the pathogenesis of congestive heart failure (CHF). Accordingly, we have examined IL-6-related cytokines in chronic CHF in humans by analysing gene and protein ...

journal_title：European journal of clinical investigation

authors： Eiken HG,Øie E,Damås JK,Yndestad A,Bjerkeli V,Aass H,Simonsen S,Geiran OR,Tønnessen T,Christensen G,Frøland SS,Gullestad L,Attramadal H,Aukrust P

更新日期：2001-05-01 00:00:00

abstract：:The activity of delta-aminolaevulinate synthase was determined in the livers of fed female rats and was found to vary with the phase of their sexual cycle. The highest enzymic activity was obtained during preoestrus (38.0 +/- 3.2 nmol delta-aminolaevulinateg.g liver.-1 hour-1), the lowest during dioestrus (17.4 +/- 3....

journal_title：European journal of clinical investigation

authors： Held H,Przerwa M

更新日期：1976-09-10 00:00:00

abstract：:In nine patients with non-malignant diseases undergoing major upper abdominal surgery, the mechanism of the postoperative fibrinolytic shut-down was investigated because of its potential significance for postoperative deep vein thrombosis by employing new and specific methods for assessing and stimulating the fibrinol...

journal_title：European journal of clinical investigation

authors： D'Angelo A,Kluft C,Verheijen JH,Rijken DC,Mozzi E,Mannucci PM

更新日期：1985-12-01 00:00:00

abstract：:Deficiency of apolipoprotein C-II (apo C-II), the cofactor for lipoprotein lipase, results in the familial chylomicronaemia syndrome characterized by severe hypertriglyceridaemia and fasting chylomicronaemia. To investigate the biochemical features of the heterozygous state for apo C-II deficiency, we characterized th...

journal_title：European journal of clinical investigation

authors： Gabelli C,Bilato C,Santamarina-Fojo S,Martini S,Brewer HB Jr,Crepaldi G,Baggio G

更新日期：1993-09-01 00:00:00

abstract：:Three different types of cardiovascular sequelae attributed to interferon therapy have been reported: arrhythmia, ischaemic heart disease and cardiomyopathy. We evaluated the left ventricular ejection fraction (LVEF) during alpha interferon therapy (3 MU administered subcutaneously three times a week for 6 months) in ...

journal_title：European journal of clinical investigation

authors： Sartori M,Andorno S,La Terra G,Pozzoli G,Rudoni M,Sacchetti GM,Inglese E,Aglietta M

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:In inflammatory bowel diseases, changes in autonomic enteric regulation may also affect neural cardiovascular control. However, while cardiac autonomic modulation has been shown to be impaired in active ulcerative colitis, the occurrence of cardiovascular autonomic alterations, also in the quiescent phase of...

journal_title：European journal of clinical investigation

authors： Coruzzi P,Castiglioni P,Parati G,Brambilla V,Brambilla L,Gualerzi M,Cademartiri F,Franzè A,De Angelis G,Di Rienzo M,Di Mario F

更新日期：2007-12-01 00:00:00

abstract：:Increased activity of the Na+/H+ antiport may be a major abnormality in essential hypertension. The activity of this transport system was investigated in lymphocytes from 13 patients with untreated essential hypertension (Ht) and 13 normotensive control subjects (Nt) on an ad libitum (130-170 mmol d-1) NaCl intake. Fu...

journal_title：European journal of clinical investigation

authors： Göbel BO,Hoffmann G,Ruppert M,Stumpe KO,Vetter H,Siffert W,Düsing R

更新日期：1994-08-01 00:00:00

abstract：:Fabry disease is an X-linked lysosomal storage disorder characterized by multi-organ dysfunction, including hearing loss - mainly sensorineural. The recent introduction of enzyme replacement therapy (ERT) has resulted in improvements in renal and cardiac function, pain and quality of life. One study has also suggested...

journal_title：European journal of clinical investigation

authors： Hajioff D,Hegemann S,Conti G,Beck M,Sunder-Plassmann G,Widmer U,Mehta A,Keilmann A

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Our aim in the present study was to determine whether endothelial NO synthase gene (ecNOS) polymorphisms are associated with myocardial infarction (MI). METHODS:Forty chromosomes from patients with MI were screened for polymorphisms of the ecNOS gene using polymerase chain reaction-single-strand conformatio...

journal_title：European journal of clinical investigation

authors： Poirier O,Mao C,Mallet C,Nicaud V,Herrmann SM,Evans A,Ruidavets JB,Arveiler D,Luc G,Tiret L,Soubrier F,Cambien F

更新日期：1999-04-01 00:00:00

abstract：:Serum prolactin levels were measured by radioimmunoassay in eighty patients (thirty-four males, forty-six females) with sarcoidosis before treatment. In twelve patients (15%) serum prolactin levels were more than two standard deviations above the mean of normal subjects. Hyperprolactinaemia was found most frequently (...

journal_title：European journal of clinical investigation

authors： Nakao K,Noma K,Sato B,Yano S,Yamamura Y,Tachibana T

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Soluble TWEAK (sTWEAK) and asymmetric dimethyl arginine (ADMA) concentrations have been associated with endothelial function in patients with chronic kidney disease (CKD). We tested the hypothesis that the improvement in endothelial function observed after renal transplantation is directly linked to the norm...

journal_title：European journal of clinical investigation

authors： Yilmaz MI,Sonmez A,Saglam M,Yaman H,Unal HU,Gok M,Cetinkaya H,Eyileten T,Oguz Y,Sari S,Yildirim AO,Vural A,Carrero JJ,Blanco-Colio LM

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Cancer is often caused by disturbance in the regulation and/or execution of programmed cell death (PCD, including apoptosis and autophagy). Our aim was to investigate these two pathways simultaneously in the same samples to understand further the pathological roles of PCDs in colorectal cancer. MATERIALS AN...

journal_title：European journal of clinical investigation

authors： Chang YT,Tseng HC,Huang CC,Chen YP,Chiang HC,Chou FP

更新日期：2011-01-01 00:00:00

abstract：:Obesity is a multifactorial disease with a marked genetic component. The situation is further complicated by the heterogeneity of obesity demonstrated by the topographical distribution of body fat, e.g. upper body (central) and lower body (gluteal) obesity. Furthermore, the distribution of fat shows a stronger heritab...

journal_title：European journal of clinical investigation

authors： Weaver JU,Kopelman PG,Hitman GA

更新日期：1992-04-01 00:00:00

abstract：:Pulmonary plasma kinetics of endogenous noradrenaline (NA) and tritium labelled L-noradrenaline (3H-NA) was studied in fifteen subjects during pulmonary arterial catheterization. Plasma NA concentration in femoral artery ranged from 0.5 to 8.2 nmol l-1, mean 2.3 nmol l-1, which was not significantly different from tha...

journal_title：European journal of clinical investigation

authors： Henriksen JH,Christensen NJ,Ring-Larsen H

更新日期：1986-10-01 00:00:00

abstract：:The classical view of aldosterone actions via the mineralocorticoid receptor (MR) limited to control of fluid balance and blood pressure homoeostasis has been progressively overcome by clinical and experimental evidence emphasizing the pleiotropic role of MR activation in the pathogenesis of cardiovascular disease. Cl...

journal_title：European journal of clinical investigation

authors： Galuppo P,Bauersachs J

更新日期：2012-10-01 00:00:00

abstract：:Pancreatic polypeptide was infused intravenously in healthy fasting subjects at 1 pmol kg-1 (n = 7) and 4 pmol kg-1 min-1 (n = 10) producing plasma PP concentrations of 223 +/- 37 pmol/l (mean +/- SEM) and 891 +/- 64 pmol/l respectively. These levels are similar to and four-fold higher than those seen after a normal m...

journal_title：European journal of clinical investigation

authors： Adrian TE,Greenberg GR,Barnes AJ,Christofides ND,Alberti KG,Bloom SR

更新日期：1980-06-01 00:00:00

abstract：:Fibronectin is a glycoprotein found in body fluids, loose connective tissue matrix and in basement membranes. Fibronectin in rheumatoid arthritis synovial fluid was immunologically indistinguishable from the plasma form, as shown by double-diffusion analysis. Fibronectin isolated from rheumatoid synovial fluid by affi...

journal_title：European journal of clinical investigation

authors： Vartio T,Vaheri A,Von Essen R,Isomäki H,Stenman S

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:Preliminary data suggest that serum uric acid (SUA) could be involved in the prognosis of chronic heart failure (HF). The aim of our study was to test the relationship between SUA and left ventricular ejection fraction (EF%) in a cohort of elderly hypertensive outpatients with chronic HF. DESIGN:We consecut...

journal_title：European journal of clinical investigation

authors： Borghi C,Cosentino ER,Rinaldi ER,Cicero AF

更新日期：2014-06-01 00:00:00