Immunization of rats with the 260-kilodalton Entamoeba histolytica galactose-inhibitable lectin elicits an intestinal secretory immunoglobulin A response that has in vitro adherence-inhibitory activity.

abstract：:The bacterium Listeria monocytogenes causes meningoencephalitis in humans. In rodents, listeriosis is associated with granulomatous lesions in the liver and the spleen, but not with meningoencephalitis. Here, infant rats were infected intracisternally to generate experimental listeric meningoencephalitis. Dose-depende...

journal_title：Infection and immunity

authors： Remer KA,Jungi TW,Fatzer R,Täuber MG,Leib SL

更新日期：2001-06-01 00:00:00

abstract：:Purified and concentrated Venezuelan equine encephalitis (VEE) virus derived from tissue cultures, rendered noninfectious by ionizing radiation with retention of in vitro serological activity, also retained a high level of immunogenicity. In mice, fluid vaccines afforded excellent protection against lethal challenge w...

journal_title：Infection and immunity

authors： Gruber J

更新日期：1971-04-01 00:00:00

abstract：:The unique permissiveness of A/J mouse macrophages for replication of Legionella pneumophila is caused by a deficiency in the Nod-like receptor (NLR) protein and intracellular sensor for L. pneumophila flagellin (Naip5). The signaling pathways and proteins activated by Naip5 sensing in macrophages were investigated. T...

journal_title：Infection and immunity

authors： Fortier A,Doiron K,Saleh M,Grinstein S,Gros P

更新日期：2009-11-01 00:00:00

abstract：:Inbred BALB/c mice were either immunized with Triton X-100-extracted antigens of blood-stage Plasmodium yoelii or infected with P. yoelii and cured in three successive schedules. Whereas the immunized BALB/c became only partially protected from subsequent challenge infection with blood-stage P. yoelii, the convalescen...

journal_title：Infection and immunity

authors： Kironde FA,Kumar A,Nayak AR,Kraikov JL

更新日期：1991-11-01 00:00:00

abstract：:We evaluated sexual recombination in the apicomplexan parasite Theileria parva using genome-wide marker analysis of haploid sporozoite populations obtained from infected Rhipicephalus appendiculatus ticks. Analysis of 231 parasite clones derived by in vitro infection of bovine lymphocytes revealed 48 distinct combinat...

journal_title：Infection and immunity

authors： Katzer F,Ngugi D,Oura C,Bishop RP,Taracha EL,Walker AR,McKeever DJ

更新日期：2006-10-01 00:00:00

abstract：:In order to construct an effector strain for the replacement therapy of dental caries, we wished to combine the properties of low-level acid production and high-level colonization potential in a strain of Streptococcus mutans. To this end, we made a deletion in the lactate dehydrogenase (LDH) gene cloned from the bact...

journal_title：Infection and immunity

authors： Hillman JD,Chen A,Duncan M,Lee SW

更新日期：1994-01-01 00:00:00

abstract：:Salmonella choleraesuis chi 3781, an attenuated [delta cya-12 delta(crp-cdt)19] mutant, was electroporated with the plasmid pBA31-R7, which codes for the expression of a 31-kDa protein from Brucella abortus (BCSP31). Recombinant S. choleraesuis chi 3781 stably maintained the pBA31-R7 plasmid and continued to express t...

journal_title：Infection and immunity

authors： Stabel TJ,Mayfield JE,Morfitt DC,Wannemuehler MJ

更新日期：1993-02-01 00:00:00

abstract：:In this analysis we have examined in detail the effects of low concentrations of zinc on the growth and dimorphism of Candida albicans. Evidence is presented that micromolar concentrations of zinc added to growth cultures grown at 25 degrees C (i) cause a twofold increase in the final concentration of spheres at satio...

journal_title：Infection and immunity

authors： Bedell GW,Soll DR

更新日期：1979-10-01 00:00:00

abstract：:The stimulation of mononuclear phagocytes by lipopolysaccharide (LPS) is facilitated by the binding of complexes of LPS and LPS-binding protein to CD14. Although it is clear that CD14 is involved in LPS-induced signaling, other investigators have hypothesized the existence of additional signaling pathways in macrophag...

journal_title：Infection and immunity

authors： Lynn WA,Liu Y,Golenbock DT

更新日期：1993-10-01 00:00:00

abstract：:We have isolated plasma cell hybridomas which secrete monoclonal antibodies directed against Haemophilus ducreyi. Two of these monoclonal antibodies recognize all strains of H. ducreyi tested to date and are capable of detecting the presence of H. ducreyi in skin lesions produced by this pathogen in experimental anima...

journal_title：Infection and immunity

authors： Hansen EJ,Loftus TA

更新日期：1984-04-01 00:00:00

abstract：:We previously identified a cell wall-associated protein from Fusobacterium nucleatum, a Gram-negative bacterium of the oral cavity, that induces human beta defensin 2 (hBD-2) in primary human oral epithelial cells (HOECs) and designated it FAD-I (Fusobacterium-associated defensin inducer). Here, we report differential...

journal_title：Infection and immunity

authors： Bhattacharyya S,Ghosh SK,Shokeen B,Eapan B,Lux R,Kiselar J,Nithianantham S,Young A,Pandiyan P,McCormick TS,Weinberg A

更新日期：2016-04-22 00:00:00

abstract：:In this study, the role of the hepatobiliary system in the early pathogenesis of Salmonella enteritidis infection was investigated in a rat model. Intravenous (i.v.) challenge with lipopolysaccharide (LPS) has previously been shown to enhance the translocation of normal gut flora. We first confirmed that LPS can simil...

journal_title：Infection and immunity

authors： Islam AF,Moss ND,Dai Y,Smith MS,Collins AM,Jackson GD

更新日期：2000-01-01 00:00:00

abstract：:Organisms of the Mycobacterium avium complex are associated with disseminated infection in patients with AIDS. The mechanisms that account for the survival of the intracellular bacteria are unknown. We document here that infection of C57BL/6 black mice with M. avium 101 triggered interleukin-10 (IL-10) production. The...

journal_title：Infection and immunity

authors： Bermudez LE,Champsi J

更新日期：1993-07-01 00:00:00

abstract：:Ureaplasma urealyticum has previously been isolated from the cultured cerebrospinal fluid of 13 of 418 newborn infants; additional bloodstream isolates were obtained from the same population. Ten of the 13 cerebrospinal fluid and 3 bloodstream isolates were available for serotyping in the present study. By the use of ...

journal_title：Infection and immunity

authors： Zheng X,Watson HL,Waites KB,Cassell GH

更新日期：1992-08-01 00:00:00

abstract：:Protection against cholera has been correlated with the level of serum vibriocidal antibodies. The specificity of these vibriocidal antibodies was mostly to the lipopolysaccharide (LPS). We synthesized conjugates of detoxified LPS with cholera toxin (CT) and other proteins in order to elicit serum LPS antibodies with ...

journal_title：Infection and immunity

authors： Gupta RK,Szu SC,Finkelstein RA,Robbins JB

更新日期：1992-08-01 00:00:00

abstract：:This study has demonstrated the extreme sensitivity of Chlamydia trachomatis growing in McCoy cells to small changes in external amino acid supply. In the absence of cycloheximide, a decrease in the amino acid concentration of medium to 75% of control values was sufficient to induce the growth of enlarged chlamydial f...

journal_title：Infection and immunity

authors： Harper A,Pogson CI,Jones ML,Pearce JH

更新日期：2000-03-01 00:00:00

abstract：:Neisseria meningitidis is a human-specific pathogen and leading cause of meningitis and septicemia. Factor H binding protein (fHbp), a virulence factor which protects N. meningitidis from innate immunity by binding the human complement regulator factor H (fH) with high affinity, is also a key antigen in vaccines being...

journal_title：Infection and immunity

authors： van der Veen S,Johnson S,Jongerius I,Malik T,Genovese A,Santini L,Staunton D,Ufret-Vincenty RL,Pickering MC,Lea SM,Tang CM

更新日期：2014-03-01 00:00:00

abstract：:Cells of the laboratory strain 3153A of Candida albicans can be stimulated to undergo high-frequency phenotypic switching by a low dose of UV. We have compared the adhesive properties of cells exhibiting the basic original smooth (o-smooth) phenotype and three switch phenotypes (star, irregular wrinkle, and revertant ...

journal_title：Infection and immunity

authors： Vargas K,Wertz PW,Drake D,Morrow B,Soll DR

更新日期：1994-04-01 00:00:00

abstract：:Klebsiella pneumoniae is a leading cause of both community-acquired and nosocomial gram-negative-bacterial pneumonia. A further clinical complication of pulmonary K. pneumoniae infection is dissemination of bacteria from the lung into the peripheral blood, resulting in bacteremia concurrent with the localized pulmonar...

journal_title：Infection and immunity

authors： Moore TA,Perry ML,Getsoian AG,Newstead MW,Standiford TJ

更新日期：2002-11-01 00:00:00

abstract：:Conventional adult mice were pretreated with metronidazole to make their intestinal tracts receptive to colonization by Clostridium botulinum. These mice, in groups of 10, were fed 0 (controls), 10(2), 10(3), 10(4), or 10(5) C. botulinum type B spores and were placed for observation in filter-lid cages whose screen fl...

journal_title：Infection and immunity

authors： Wang Y,Sugiyama H

更新日期：1984-12-01 00:00:00

abstract：:Escherichia coli isolates from patients with bacteriuria of pregnancy were compared by PCR with isolates from patients with community-acquired cystitis for the presence of established virulence determinants. The strains from patients with bacteriuria of pregnancy were less likely to carry genes for P-family, S-family,...

journal_title：Infection and immunity

authors： Graham JC,Leathart JB,Keegan SJ,Pearson J,Bint A,Gally DL

更新日期：2001-02-01 00:00:00

abstract：:The role of gamma-delta T cells in host resistance to Chlamydia trachomatis was characterized by using a murine model of pneumonia caused by the mouse pneumonitis agent (MoPn), murine C. trachomatis. At days 3 and 7 after infection, gamma-delta T-cell-deficient knockout mice had significantly higher levels of MoPn in ...

journal_title：Infection and immunity

authors： Williams DM,Grubbs BG,Kelly K,Pack E,Rank RG

更新日期：1996-09-01 00:00:00

abstract：:Cell-mediated immunity is pivotal in host resistance to Blastomyces dermatitidis infection. Immunization of mice with the WI-1 adhesin enhances resistance against experimental pulmonary infection but elicits features of a mixed T-helper-cell immune response. Immune mice acquire delayed-type hypersensitivity (DTH) but ...

journal_title：Infection and immunity

authors： Wüthrich M,Finkel-Jiminez BE,Klein BS

更新日期：2000-12-01 00:00:00

abstract：:Cholera toxin (CT) is a potent adjuvant for mucosal vaccination; however, its mechanism of action has not been clarified completely. It is well established that peripheral monocytes differentiate into dendritic cells (DCs) both in vitro and in vivo and that monocytes are the in vivo precursors of mucosal CD103(-) proi...

journal_title：Infection and immunity

authors： Veglia F,Sciaraffia E,Riccomi A,Pinto D,Negri DR,De Magistris MT,Vendetti S

更新日期：2011-03-01 00:00:00

abstract：:Coxiella burnetii is an intracellular pathogen that replicates in a lysosome-derived vacuole. A determinant necessary for C. burnetii virulence is the Dot/Icm type IVB secretion system (T4SS). The Dot/Icm system delivers more than 100 proteins, called type IV effectors (T4Es), across the vacuolar membrane into the hos...

journal_title：Infection and immunity

authors： Crabill E,Schofield WB,Newton HJ,Goodman AL,Roy CR

更新日期：2018-03-22 00:00:00

abstract：:Lipopolysaccharide (LPS) is cleared from the blood mainly by the liver. The Kupffer cells are primarily responsible for this clearance; liver endothelial and parenchymal cells contribute to a lesser extent. Although several binding sites have been described, only CD14 is known to be involved in LPS signalling. Among t...

journal_title：Infection and immunity

authors： van Oosten M,van de Bilt E,van Berkel TJ,Kuiper J

更新日期：1998-11-01 00:00:00

abstract：:A radioimmunoprecipitation method has been devised which permits the direct identification of those proteins which are both exposed on the cell surface of Haemophilus influenzae type b and accessible to antibody. Both extrinsically and intrinsically radiolabeled cells of this organism were employed as the sources of a...

journal_title：Infection and immunity

authors： Hansen EJ,Frisch CF,Johnston KH

更新日期：1981-09-01 00:00:00

abstract：:Moraxella catarrhalis is a causative agent of otitis media in children and lower respiratory tract infections in adults suffering from chronic obstructive pulmonary disease (COPD). This strict human pathogen continues to be a significant cause of disease in this broad spectrum of patients because there is no available...

journal_title：Infection and immunity

authors： Schwingel JM,Edwards KJ,Cox AD,Masoud H,Richards JC,St Michael F,Tekwe CD,Sethi S,Murphy TF,Campagnari AA

更新日期：2009-10-01 00:00:00

abstract：:The obligate intracellular parasite Toxoplasma gondii critically relies on host cell invasion during infection. Proteins secreted from the apical micronemes are central components for host cell recognition, invasion, egress, and virulence. Although previous work established that the sporozoite protein with an altered ...

journal_title：Infection and immunity

authors： Huynh MH,Boulanger MJ,Carruthers VB

更新日期：2014-10-01 00:00:00

abstract：:A cohort of 111 children from Bangui, Central African Republic, was surveyed for enteric Campylobacter infections from birth to the age of 2 years; stools were examined biweekly in these children until 6 months of age and at least four times per year thereafter until 2 years of age and after each diarrheal episode. Bl...

journal_title：Infection and immunity

authors： Martin PM,Mathiot J,Ipero J,Kirimat M,Georges AJ,Georges-Courbot MC

更新日期：1989-08-01 00:00:00