Abstract:
:In nematodes, the 22 nucleotide (nt) spliced leader (SL) is normally encoded by a multi-copy, tandemly reiterated SL gene and is trans-spliced from SL-RNA onto the 5' end of a subset of mRNAs. We have found that the SL is also encoded at multiple (> 100) orphon genomic sites in the parasitic nematode Angiostrongylus cantonensis. At these sites the sequence forms part of a 198 bp repetitive element (designated con-198). Transcription from two genomic elements that contain the con-198 sequence has been characterised. At one element (G-2) an approximately 850 nt RNA with an internal SL is transcribed. At the other (G-1), transcription takes place 3 kb downstream of the con-198 sequence.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Joshua GW,Perler FB,Wang CCdoi
10.1093/nar/23.6.1030subject
Has Abstractpub_date
1995-03-25 00:00:00pages
1030-5issue
6eissn
0305-1048issn
1362-4962pii
4a0690journal_volume
23pub_type
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