Preliminary observation on human saliva alpha-fetoprotein in patients with hepatocellular carcinoma.

abstract：BACKGROUND:Type 1 diabetes has been recognized as an organ specific autoimmune disease owing to the immune destruction of pancreatic islet beta cells in genetically susceptible individuals. In both human and rodent models of type 1 diabetes, such as nonobese diabetic (NOD) mice, biobreeding rats, the disease has a dist...

journal_title：Chinese medical journal

authors： Li D,Zhu SW,Liu DJ,Liu GL,Shan ZY

更新日期：2005-08-05 00:00:00

abstract：BACKGROUND:The importance of polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene for the prediction of the response to fluorouracil-based adjuvant chemotherapy in gastric cancer patients remains unclear. The aim of this study is to assess the predictive value of several polymorphisms of the MTHFR gene...

journal_title：Chinese medical journal

authors： Zhang X,Bai Z,Chen B,Feng J,Yan F,Jiang Z,Zhong Y,Wu J,Cheng L,Lu Z,Tong N,Zhang Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Studies on selected patients undergoing off-pump versus on-pump coronary artery bypass surgery have produced inconsistent results, especially in patients with multiple coronary artery disease. This study compared the clinical results of on-pump and off-pump coronary bypass surgery in patients with triple-ves...

journal_title：Chinese medical journal

authors： Chen X,Xu M,Shi HW,Mu XW,Chen ZQ,Qiu ZB

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:With the significant improvement in the survival of patients with nasopharyngeal carcinoma (NPC) undergoing radiotherapy and the growing availability of the sophisticated imaging modalities, the number of radiation encephalopathy (RE) cases relating to NPC radiotherapy is increasing. In this study, we invest...

journal_title：Chinese medical journal

authors： Wang XL,Yin JL,Li H,Li XD,Quan JT

更新日期：2007-03-20 00:00:00

abstract：OBJECTIVE:To investigate the status of the drug resistance and the ampC gene expression of Enterobacter cloacae. METHODS:Disk diffusion tests were made for detecting the susceptibility of antimicrobial agents against Enterobacter cloacae. AmpC gene was amplified by polymerase chain reaction (PCR) and verified by DNA s...

journal_title：Chinese medical journal

authors： Zhou Z,Li L,Yu Y,Ma Y

更新日期：2003-08-01 00:00:00

abstract：:Twenty-seven samples of pleomorphic salivary adenoma (PSA) were examined for expression and structure of c-myc, c-Ha-ras, c-erbB-2, c-sis oncogenes by RNA dot blot, DNA dot blot and Southern blot hybridization. Eighteen of 25 PSA showed 5.02 +/- 4.74 fold overexpression of c-myc oncogene, 6 of 19 PSA had 4.91 +/- 3.87...

journal_title：Chinese medical journal

authors： Xue H,Situ ZQ,Wang CJ,Wu JZ

更新日期：1993-01-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most common sustained dysrhythmia in clinical practice. The bulk of evidence suggests that inflammatory processes, oxidative stress and matrix metalloproteinase are associated with development of AF. However, these agents may be involved in high mobility group box 1 protein (HMGB1). We ...

journal_title：Chinese medical journal

authors： Hu XR,Wang XH,Liu HF,Zhou WJ,Jiang H

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. In this study, we collected a Han monilethrix family to detect the mutations in patients and investigated the correlation between the genotype and phenotype of monilethrix. METHODS:In this study, ...

journal_title：Chinese medical journal

authors： Ye ZZ,Nan X,Zhao HS,Chen XR,Song QH

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Contrast-enhanced ultrasound is a dynamic and continuous modality providing real-time view of vascularization and flow distribution patterns of different organs and tumors. In order to evaluate the diagnostic significance of intraoperative contrast-enhanced ultrasound in assessing the resection degree of bra...

journal_title：Chinese medical journal

authors： Yu SQ,Wang JS,Chen SY,Liu XM,Li Y,Ding YM,Li XY,Sun YL,Chen H

更新日期：2015-01-20 00:00:00

abstract：OBJECTIVE:To define the prevalence, severity and risk factors for lead poisoning in new immigrant children from the mainland of China to Hong Kong, China. METHODS:New immigrant children from the mainland of China under 18 years of age were invited to join the study. Their growth parameters and venous blood lead levels...

journal_title：Chinese medical journal

authors： Ling S,Chow C,Chan A,Tse K,Mok K,Ng S

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) core antigen assays have been produced to exclude infectious donations collected during the preseroconversion window phase (PWP). For the same purpose, we evaluated the specificity and sensitivity of a novel hepatitis C virus NS3 antigen detection immunoassay and the application of th...

journal_title：Chinese medical journal

authors： Xie L,Wu XD,Huang DZ,Chen HL,He LX,Wang J,Han DK

更新日期：2007-02-20 00:00:00

abstract：BACKGROUND:Left ventricular hypertrophy (LVH) and geometric abnormality are associated with morbidity and mortality of cardiovascular disease and stroke. Hypertension is the major cause of LVH. Yet the prevalence and other risk factors of LVH and geometric abnormality in Chinese hypertensive population are unknown. The...

journal_title：Chinese medical journal

authors： Wang SX,Xue H,Zou YB,Sun K,Fu CY,Wang H,Hui RT

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Our previous studies have shown that regulatory factor X5 (RFX5), a classical transcription regulator of MHCII genes, was obviously overexpressed in hepatocellular carcinoma (HCC) tumors. However, the role of RFX5 in the carcinogenesis and progress of HCC remains unknown. This study aimed to reveal its biolo...

journal_title：Chinese medical journal

authors： Chen DB,Zhao YJ,Wang XY,Liao WJ,Chen P,Deng KJ,Cong X,Fei R,Wu X,Shao QX,Wei L,Xie XW,Chen HS

更新日期：2019-07-05 00:00:00

abstract：:T-lymphocyte subsets, B-lymphocyte, immunoglobulins and complement were studied in 38 children with Henoch Schonlein Purpura (HSP) in the acute stage. They had significantly lower CD3 percentage and lymphocyte blastogenesis rate, greater CD8 variation coefficient and B-lymphocyte percentage and higher levels immunoglo...

journal_title：Chinese medical journal

authors： Sun XC,Chen MY,Cheng AS,Xu DL

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVE:Sepsis remains a leading cause of death in many Intensive Care Units worldwide. Immunosuppression has been a primary focus of sepsis research as a key pathophysiological mechanism. Given the important role of the negative costimulatory molecules programmed cell death-1 (PD-1) and programmed death-ligand 1 (PD...

journal_title：Chinese medical journal

authors： Liu Q,Li CS

更新日期：2017-04-20 00:00:00

abstract：OBJECTIVE:In order to explore the possible roles played by the autoimmune mechanism in the progression of myocarditis into dilated cardiomyopathy (DCM) using an animal model, we investigated whether autoimmune myocarditis might develop into DCM. METHODS:Experimental Balb/C mice (n = 20) were immunized with cardiac myo...

journal_title：Chinese medical journal

authors： Wang Z,Liao Y,Dong J,Li S,Wang J,Fu ML

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:To investigate osteoclastic resorption in trabeculae of osteoporotic femoral head. METHODS:Osteoporotic femoral heads were collected from 7 aged women with an average age of 72.4 years, who underwent endoprosthetic replacement for intracapsular hip fracture. Femoral head trabeculae from 3 young adults killed...

journal_title：Chinese medical journal

authors： Chai B,Tang X,Zhou W,Li H

更新日期：1996-05-01 00:00:00

abstract：:An ovarian gynandroblastoma was found in a 59-year-old woman. The tumor consisting of mixed Sertoli-Leydig cells and granulosa-theca cells demonstrated no malignant features. Bisexual cells in gynandroblastoma derived from a common gonadal mesenchyme precursor or indifferent cell. The excision of appendages with tumor...

journal_title：Chinese medical journal

authors： Zhang SQ

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that ultrasonography is the recommended imaging modality for preoperative staging of papillary thyroid carcinomas (PTCs). However, only a few studies have kept watch on preoperative evaluation of capsular invasion (CI) or extracapsular extension (ECE) and cervical lymph nod...

journal_title：Chinese medical journal

authors： Jiao WP,Zhang L

更新日期：2017-06-05 00:00:00

abstract：BACKGROUND:This study was designed to evaluate the relationship between high-density lipoprotein cholesterol (HDL-C) level and acute myocardial infarction (AMI) and coronary heart disease (CHD) death and to explore the protective effect of HDL against CHD in the elderly Chinese. METHODS:Started from 1986, 1211 retiree...

journal_title：Chinese medical journal

authors： Li JZ,Chen ML,Wang S,Dong J,Zeng P,Hou LW

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:The SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery Score II (SS-II) can well predict 4-year mortality in patients with complex coronary artery disease (CAD), and guide decision-making between coronary artery bypass graft surgery and percutaneous coronary intervention (PCI)....

journal_title：Chinese medical journal

authors： He JQ,Yu XP,Peng C,Li Q,Luo YW,Gao YC,Zhang XL,Wu CY,Zhao H,Zhang YC,Liu JH,Lyu SZ,Chen F

更新日期：2015-08-20 00:00:00

abstract：BACKGROUND:Variations in position and relationship between the internal jugular vein (IJV) and the common carotid artery (CCA) may lead to inadvertent artery puncture which could be disastrous during central venous access. We demonstrated the anatomic relationship of the IJV with CCA in order to find the optimal site a...

journal_title：Chinese medical journal

authors： Qin XH,Zhang H,Mi WD

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Acute fatty liver of pregnancy (AFLP) is a rare but life-threatening complication occurring in the third trimester. It is often fatal to both mother and fetus. The complicated clinical manifestations as well as an insufficient understanding of the disease make the precise diagnosis and effective treatment of...

journal_title：Chinese medical journal

authors： Zhang YP,Kong WQ,Zhou SP,Gong YH,Zhou R

更新日期：2016-05-20 00:00:00

abstract：BACKGROUND:Cigarette smoke induces an acute but persisting inflammation in peripheral blood and airway in chronic obstructive pulmonary disease (COPD), and CD8(+) Tc-lymphocytes are considered as a key role in this process. We aimed to investigate the Tc-lymphocytes immunodeviation in system and local airway of COPD pa...

journal_title：Chinese medical journal

authors： Yu MQ,Liu XS,Wang JM,Xu YJ

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To explore the immune promotion mechanism of retinoic acid (RA). METHODS:Reverse Transcription-Polymerase chain reaction (RT-PCR) was used to detect the gene expression of insulin like growth factor I (IGF-I) and IGF receptors (IGF-IR and IGF-IIR) in vitro, and their regulation by RA in human cord blood lymp...

journal_title：Chinese medical journal

authors： Yang Y,Wang W,Su Y

更新日期：2001-02-01 00:00:00

abstract：:Twenty-one patients, under 6 years of age, with root avulsion of the brachial plexus were treated from 1975 to 1987. Among them, 9 had root avulsion of the upper trunk, 2 root avulsion of the lower trunk with middle trunk broken, and 10 root avulsion of the whole brachial plexus. Follow-up of 16 patients showed excell...

journal_title：Chinese medical journal

authors： Zhang GM,Gu YD,Chen DS,Yan JG,Cheng XM

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Although breast-conserving surgery is one of the standard treatments for breast cancer, few studies have assessed its recent implementation in China. We aimed to clarify the current real-world status of breast-conserving surgery in China. METHODS:This cross-sectional survey relied on data collected by the C...

journal_title：Chinese medical journal

authors： Yu LX,Shi P,Tian XS,Yu ZG,Chinese Society of Breast Surgery.

更新日期：2020-11-20 00:00:00

abstract：BACKGROUND:In-hospital medical complications are associated with poorer clinical outcomes for stroke patients after disease onset. However, few studies from China have reported the effect of these complications on the mortality of patients with acute ischemic stroke. In this prospective work, the China National Stroke ...

journal_title：Chinese medical journal

authors： Wang PL,Zhao XQ,Yang ZH,Wang AX,Wang CX,Liu LP,Wang YL,Wang XG,Ju Y,Chen SY,Chen QD,Qu H,Lu JJ,Zhang J,Ma RH,Zhang YM,Wang YJ

更新日期：2012-07-01 00:00:00

abstract：:Increasing evidence suggests that long non-coding RNAs (lncRNAs) are of vital importance for various biological processes, and dysregulation of lncRNAs is frequently associated with various diseases such as psoriasis. LncRNAs modulate gene expression at the transcriptional, post-transcriptional, and translational leve...

journal_title：Chinese medical journal

authors： Song JK,Yin SY,Li W,Li XD,Luo Y,Luo Y,Xing M,Li B,Kuai L

更新日期：2020-12-14 00:00:00

abstract：BACKGROUND:The cell layer of the ciliary epithelium is responsible for aqueous humor secretion and maintenance. Ion channels play an important role in these processes. The main aim of this study was to determine whether the well-characterized members of the Kv1 family (Kv1.3) contribute to the Kv currents in ciliary ep...

journal_title：Chinese medical journal

authors： Li YF,Zhuo YH,Bi WN,Bai YJ,Li YN,Wang ZJ

更新日期：2008-11-20 00:00:00