Abstract:
:Sleep duration and indices of disturbed sleep, such as night-time waking and day-time sleep, were investigated in amphetamine users following hospital admission and withdrawal from the drug. Compared to controls, the amphetamine group showed an initial period of oversleeping and, towards the end of the first week, they showed a considerable degree of reduced sleep which persisted for the 20 days of this study. There was greater variability in sleep duration within the amphetamine group on almost all nights, and the variability in sleep duration from one night to the next was also greater. More night-time sleep disturbance was evident among the amphetamine ex-users. These results are discussed with respect to previous work and the pattern is seen to be more complex than had been imagined. A tentative neurochemical model is suggested and clinical implications are considered.
journal_name
Drug Alcohol Dependjournal_title
Drug and alcohol dependenceauthors
Gossop MR,Bradley BP,Brewis RKdoi
10.1016/0376-8716(82)90010-2subject
Has Abstractpub_date
1982-10-01 00:00:00pages
177-83issue
2-3eissn
0376-8716issn
1879-0046pii
0376-8716(82)90010-2journal_volume
10pub_type
杂志文章abstract:BACKGROUND:There is concern that medical marijuana laws (MMLs) could negatively affect adolescents. To better understand these policies, we assess how adolescent exposure to MMLs is related to educational attainment. METHODS:Data from the 2000 Census and 2001-2014 American Community Surveys were restricted to individu...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2016.09.002
更新日期:2016-11-01 00:00:00
abstract::Behavioral and physiological indices which could be symptoms of individual Wistar rats' sensitivity to the development of physical dependence on morphine, were studied. This state was induced in three different ways: (1) by i.p. injection of increasing doses of the drug; (2) by i.p. injection of morphine as a reward o...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/0376-8716(91)90023-r
更新日期:1991-12-01 00:00:00
abstract::Ninety alcoholic patients with the secondary affective disorders (anxiety, depression) were divided into four groups. Patients in the first group received GABAB receptor ligands (baclofen), those in the second group, diazepam, those in the third group, amitriptyline and those in the fourth group, placebo. The results ...
journal_title:Drug and alcohol dependence
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0376-8716(93)90057-w
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:Chronic pain is common in patients with prescription opioid use disorder (OUD), and pain severity has been shown to predict opioid use for those with chronic pain. However, recent research suggests that focusing on pain status (i.e., the presence or absence of chronic pain) at treatment initiation may not re...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章,多中心研究
doi:10.1016/j.drugalcdep.2019.107675
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND AND AIMS:Adolescent Binge drinking has become an increasing health and social concern, which cause several detrimental consequences for brain integrity. However, research on neurophysiological traits of vulnerability for binge drinking predisposition is limited at this time. In this work, we conducted a two-...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2020.108401
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Cigarette smokers are more likely to experience pain than nonsmokers, and experimental research indicates that pain is a potent motivator of smoking. Urge to smoke is a predictor of early relapse, yet associations between pain and urge to smoke have yet to be tested among daily smokers. This study aimed to c...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2018.01.037
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:International borders are unique social and environmental contexts characterized by high levels of mobility. Among drug users, mobility increases risk for human immunodeficiency virus (HIV) in part through its effects on the social environment. However, the social dynamics of drug users living in border regi...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2010.08.009
更新日期:2011-01-15 00:00:00
abstract::We investigated the associations of self-reported HIV status and risky injection practices with dependent variables measuring readiness and motivation for treatment and depression among 550 clients at two residential drug abuse treatment programs. The results suggest that a positive HIV status may be associated with m...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/0376-8716(94)90133-3
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:The effects of parent-based interventions on adolescent alcohol use are unclear, including what factors moderate intervention effects. This study examines the effects of parent-based interventions on adolescent alcohol use and whether the treatment effects vary by participants' characteristics and interventi...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.drugalcdep.2018.05.031
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:Previous research links cigarette use and marijuana use in adolescence with the use of other illicit substances. Limited research, however, has explored whether vaping nicotine and marijuana, along with using these substances through multiple modes of delivery (traditional cigarette/marijuana use and vaping) is...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2020.108469
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:Brief motivational intervention (BMI) is one of the few effective strategies targeting alcohol consumption, but has not been tested in young men in the community. We evaluated the efficacy of BMI in reducing alcohol use and related problems among binge drinkers and in maintaining low-risk drinking among non-...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.drugalcdep.2010.07.009
更新日期:2011-01-01 00:00:00
abstract::Olfactory evoked potentials (OEP) were elicited by odorous and nonodorous stimuli in 50 adult subjects: 26 subjects with histories of either cocaine (n = 19) or alcohol (n = 7) dependence, 10 with histories of nicotine but no other drug dependence, 2 with clinical anosmia of peripheral origin, and 12 subjects without ...
journal_title:Drug and alcohol dependence
pub_type: 临床试验,杂志文章
doi:10.1016/0376-8716(96)01258-6
更新日期:1996-09-01 00:00:00
abstract:BACKGROUND:The aim of the study was to investigate the prevalence of injecting drug use and associated risk behaviour among a sentinel sample of ecstasy users. METHODS:Cross-sectional surveys were conducted with regular ecstasy users as part of an annual monitoring study of ecstasy and related drug markets in all Aust...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2005.11.014
更新日期:2006-07-27 00:00:00
abstract::The pattern of gangliosides in membranes of erythrocytes was examined in healthy and in alcoholic subjects on the second and on the 28th day of detoxification therapy. The GM3 and GD3 fraction were decreased significantly in alcoholics on the 2nd day. After 4 weeks of abstinence all changes had returned to the level o...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/0376-8716(90)90087-u
更新日期:1990-08-01 00:00:00
abstract:INTRODUCTION:Behavioral economics provides a framework for quantifying drug abuse potential that can inform public health risk, clinical treatment, and research. Hypothetical purchase task (HPT) questionnaires may provide a low-cost and sensitive method by which to measure and predict the appeal of pharmaceutical drugs...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2019.01.022
更新日期:2019-05-01 00:00:00
abstract::Individuals with co-occurring substance use and psychiatric disorders have a more severe clinical course and poorer outcomes than do individuals with one disorder. In an attempt to find intervening variables that may contribute to improvement in treatment outcomes among individuals with co-occurring disorders, we inve...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2007.01.009
更新日期:2007-07-10 00:00:00
abstract::One hundred forty-two low income women were interviewed postpartum to determine their attitudes regarding the potential effects of a punitive law on the behavior of substance-using pregnant women. The convenience sample was primarily black (85.2%) and single (81%) and 14.8% admitted use of illicit drugs during pregnan...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/0376-8716(93)90001-7
更新日期:1993-02-01 00:00:00
abstract::Despite the fact that tobacco and marihuana are often used together, relatively little is known about the effects of this combination. In order to investigate the effects of the principal psychoactive component in tobacco smoke, nicotine, on marihuana-induced intoxication, we conducted a double blind, cross-over exper...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.drugalcdep.2005.01.008
更新日期:2005-08-01 00:00:00
abstract::This paper reports on the results of group therapy for the wives of alcoholics where the alcoholics themselves were offered no treatment. The reason for running such a group is based on the idea that wives might seek help before their husbands, might attend sessions regularly and by acquiring better knowledge of alcoh...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/0376-8716(86)90084-0
更新日期:1986-07-01 00:00:00
abstract::Data from research with laboratory animals indicate that cocaine self-administration can be reduced by lambda-aminobutyric acid (GABA) agonists. Yet, the effectiveness of GABA agonists to decrease human cocaine self-administration has not been investigated under controlled laboratory conditions. The purpose of this st...
journal_title:Drug and alcohol dependence
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.drugalcdep.2003.10.015
更新日期:2004-03-08 00:00:00
abstract:AIM:Modafinil was tested for efficacy in facilitating abstinence in cocaine-dependent patients, compared to placebo. METHODS:This was a double-blind placebo-controlled study, with 12 weeks of treatment and a 4-week follow-up. Six outpatient substance abuse treatment clinics participated in the study. There were 210 tr...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.drugalcdep.2009.04.015
更新日期:2009-09-01 00:00:00
abstract:INTRODUCTION:"Dabbing" involves heating extremely concentrated forms of marijuana to high temperatures and inhaling the resulting vapor. We studied themes describing the consequences of using highly concentrated marijuana by examining the dabbing-related content on Twitter. METHODS:Tweets containing dabbing-related ke...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2016.06.034
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Patients with schizophrenia have higher rates of smoking (58-88%) than in the general population ( approximately 22%), and are more refractory to smoking cessation. These patients also exhibit numerous neurocognitive deficits, some of which may be ameliorated by cigarette smoking. The neurocognitive benefits...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.drugalcdep.2009.04.005
更新日期:2009-09-01 00:00:00
abstract::A number of experiments have evaluated self-administration of the combination of a stimulant and an opioid. Less is known about the combination of a stimulant and a CNS depressant. The present experiment was designed to examine self-administration of the mixture of cocaine and pentobarbital (PB). Rhesus monkeys (n=4) ...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2008.10.013
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:Accumulating evidence suggests that opioid overdose and HIV infection are burgeoning intertwined epidemics among people who inject drugs (PWID) in Central Asia. To date, however, research on overdose and its associations with HIV risks among PWID in Central Asia remains virtually absent. This paper aims to p...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章,评审
doi:10.1016/j.drugalcdep.2013.07.017
更新日期:2013-11-01 00:00:00
abstract::A representative sampling of the secondary school population of two states of Malaysia (sample size 16166) indicated that 11% of students had had experience of drug use. Use of a single drug was the common pattern, with cannabis reported most often by older students, and sedatives most often by younger students. A qua...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/0376-8716(80)90163-5
更新日期:1980-05-01 00:00:00
abstract:BACKGROUND:Adolescents tend to overestimate the prevalence of substance use among their peers and these perceived norms are associated with their current and future use. However, little is known about how perceived norms change over time during middle school, a developmental period when adolescents are at-risk for init...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2013.08.008
更新日期:2013-12-01 00:00:00
abstract::This study analyzes causes of deaths of 766 patients who died while in methadone treatment in Texas between 1994 and 2002. Compared with deaths in the general population of Texas, deaths of clients in methadone treatment were 4.6 times more likely to be from a drug overdose, 3.4 times more likely to be from liver dise...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2004.09.006
更新日期:2005-04-04 00:00:00
abstract:BACKGROUND:Contingency management (CM), despite the evidence base for its effectiveness, remains controversial, with sub-optimal implementation. In 2007, UK guidelines recommended the use of CM in publicly funded services, but uptake has also been minimal. Previous surveys of service providers suggest differences in op...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2011.05.016
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Improving prediction of cigarette smoking during pregnancy (SDP), including differences by race/ethnicity and geography, is necessary for interventions to achieve greater and more equitable SDP reductions. METHODS:Using individual-level data on singleton first births, 2010-2017 (N = 182,894), in a US state ...
journal_title:Drug and alcohol dependence
pub_type: 杂志文章
doi:10.1016/j.drugalcdep.2020.108273
更新日期:2020-12-01 00:00:00