Abstract:
:Reviewing the records of 131 patients with malign tumors of the mouth and oropharynx 36 (35%) alcoholics were found among 103 male patients with carcinoma. The highest incidence of alcoholism (58%) was seen in patients with carcinoma of the floor of the mouth. In alcoholics the age distribution showed a peak in the 4th decennium, whereas non-alcoholics had this peak in the 6th decennium. With 64% T3-tumors the alcoholics revealed on an average markedly more advanced tumor stages before treatment than the other patient group with only 29% T3-tumors; metastases in the regional lymphnodes were seen in 50% of the latter, but in 72% of the alcoholics. Skin reaction to radiation therapy appeared particulary pronounced more often in alcoholics (87%) than in the other patients (63%). The 3-year survival rates were 38.5% (alcoholics) and 44.5% (non-alcoholics). These observations suggest that alcoholism with its numerous accompaniments does not only play a role in etiology, but does also have unfavourable effects on the course and the prognosis of cancer of the mouth and oropharynx.
journal_name
HNOjournal_title
HNOauthors
Schultz-Coulon HJ,Schmidt Wsubject
Has Abstractpub_date
1982-01-01 00:00:00pages
9-13issue
1eissn
0017-6192issn
1433-0458journal_volume
30pub_type
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