[Insect venom allergies : Update 2016 for otorhinolaryngologists].

Abstract:

:Due to the increasing incidence of hymenoptera venom allergies and the potentially life-threatening reactions, it is important for otolaryngologists working in allergology to have an understanding of modern diagnostic and treatment standards for this allergic disease. Molecular diagnosis with recombinant single allergens from bee and wasp venom components improves the diagnostics of insect venom allergies, particularly in patients with double-positive extract-based test results. Detection of specific sensitizations to bee or wasp venom enables double sensitizations to be better distinguished from cross-reactivity. Based on patient history and test results, the patient is initially advised on avoidance strategies and prescribed an emergency medication kit. Then, the indication for allergen-specific immunotherapy (AIT) is evaluated. The dose-increase phase can be performed using conventional, cluster, rush, or ultra-rush schedules, whereby rapid desensitization (rush AIT) performed in the clinic seems to be particularly effective as initial treatment.

journal_name

HNO

journal_title

HNO

authors

Klimek L,Dippold N,Sperl A

doi

10.1007/s00106-016-0274-z

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

927-942

issue

12

eissn

0017-6192

issn

1433-0458

pii

10.1007/s00106-016-0274-z

journal_volume

64

pub_type

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