Abstract：
:Although fibrin glues have been successful in many areas of surgery, they have not become fully established in nerve anastomosis, even in ENT surgery, an area where significant advantages were expected. As the fibrin clot dissolves prematurely, and dehiscences follow, antifibrinolytic substances must be added to the adhesive. Fibrosis often complicates the use of nerve adhesives. We examined both adhesive systems for their ability to induce fibrosis and their regenerative success rate. Using 1000 KIU aprotinin and 4 IU thrombin there was no significant difference on the effect of both commercially available fibrin adhesives on the collagen content of a nerve anastomosis or on the cumulative action potential in the rat. The proportion of connective tissue was about 33%. Regeneration was undoubtedly recorded.
journal_name
HNOjournal_title
HNOauthors
Herter Tsubject
Has Abstractpub_date
1989-06-01 00:00:00pages
255-8issue
6eissn
0017-6192issn
1433-0458journal_volume
37pub_type
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