Abstract：
:Mice genetically selected according to their capacity to produce antibody were orally infected with fifty muscle larvae. After 1 month, the number of larvae found in low responder mice was twice the number found in high responder mice. Following a second infection, low responder mice were completely protected while high responder mice showed only partial protection. It is suggested that the better resistance of high responder mice after a primary infection is due to their high and rapid antibody production. However, at the time of a secondary infection both lines of mice possess enough antibody to act on the effector cells (macrophages, eosinophils, etc.) and resistance is then dependent on the metabolic activity of these cells, which is more intense in the low responder mice.
journal_name
Immunologyjournal_title
Immunologyauthors
Perrudet-Badoux A,Binaghi RA,Boussac-Aron Ysubject
Has Abstractpub_date
1978-09-01 00:00:00pages
519-22issue
3eissn
0019-2805issn
1365-2567journal_volume
35pub_type
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