Phenytoin induced gingival overgrowth in institutionalized epileptics.

Abstract:

:In a cross-sectional, epidemiological study of phenytoin induced gingival overgrowth in 77 institutionalized persons with epilepsy, the severity of the gum lesions was quantified by means of a precise new technique. Lesion severity was then compared statistically to other clinical and laboratory parameters. Positive correlations were detected between overgrowth severity and gingival inflammation, probing depths, calculus accumulation, plaque score and the measurement gingival margin to mucogingival junction (GM-MGJ). No correlation was observed between lesion severity and patients age, daily drug dosage, plasma or saliva phenytoin level, or salivary concentration of the major phenytoin metabolite.

journal_name

J Clin Periodontol

authors

Hassell T,O'Donnell J,Pearlman J,Tesini D,Murphy T,Best H

doi

10.1111/j.1600-051x.1984.tb02214.x

subject

Has Abstract

pub_date

1984-04-01 00:00:00

pages

242-53

issue

4

eissn

0303-6979

issn

1600-051X

journal_volume

11

pub_type

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