Abstract:
:Eight rhesus monkeys (Macaca mulatta) were trained to detect an instantaneous lateral displacement of a small spot of light. The smallest movement for 79% correct performance was then determined. Severing the splenium of the corpus callosum, which has to be done to reveal the superior colliculi, had no effect on the movement threshold. But when the superior colliculi were damaged in addition, there was an initial substantial impairment in the detection of movement and a smaller but permanent elevation in the threshold. Only if the rostral superior colliculi and pretectum were spared, was there no change in threshold, and there was evidence that the pretectal rather than collicular damage may be more important in relation to movement discrimination. Tests with human observers performing the same task showed that the threshold can be elevated by imprecise fixation and accomodation, suggesting that the consequences of mid-brain damage on movement detection may be wholly or in large part attributed to oculomotor disorders.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Cowey A,Smith B,Butter CMdoi
10.1007/BF00237444subject
Has Abstractpub_date
1984-01-01 00:00:00pages
79-91issue
1eissn
0014-4819issn
1432-1106journal_volume
56pub_type
杂志文章abstract::Clear vision of objects moving in three-dimensional space near an observer is attained by a combination of smooth-pursuit and vergence eye movements. The two systems must interact with the vestibular system to maintain the image of the object on the fovea. Previous studies showed that training with smooth-pursuit vest...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-003-1777-x
更新日期:2004-05-01 00:00:00
abstract::Activities of 53 neurons in the brain stem were recorded with chronically implanted fine wires in freely eating and drinking rats. Twenty units were isolated from the trigeminal mesencephalic nucleus; 18 were spindle afferents and 2 periodontal afferents. The spindle units were classified into 4 types: 5 units showed ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247896
更新日期:1989-01-01 00:00:00
abstract::Adequate postural control is a prerequisite for daily activities such as reaching for an object. However, knowledge on the relationship between postural adjustments and the quality of reaching movements during human ontogeny is scarce. Therefore we evaluated the development of the relationship between the kinematic fe...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-007-0964-6
更新日期:2007-08-01 00:00:00
abstract::(1) Pinna stimulation evoked rhythmic oscillations in the spinal cord of the decerebrate curarized cat ("fictitious" scratch reflex). The role of different spinal segments in generation of these oscillations was studied. For this purpose, destruction of the grey matter of one or of several spinal segments was performe...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00239400
更新日期:1983-01-01 00:00:00
abstract::Force and electromyogram (EMG) responses of the medial gastrocnemius muscle were assessed during isometric contractions in 8 decerebrate cat preparations, before and after acute dorsal hemisection of the spinal cord at the T12 level. The measures derived included the relation between static force and mean rectified EM...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247497
更新日期:1988-01-01 00:00:00
abstract::The aim of this study was to define the relative contribution of self-generated cutaneous and proprioceptive feedback to haptic shape discrimination by systematically constraining the exploratory strategy. Subjects (n = 23) explored pairs of two-dimensional (2-D) angles (standard angle, 90 degrees; comparison angles, ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0728-8
更新日期:2007-04-01 00:00:00
abstract::Our previous study showed that a fully flexed or extended hand became perceived as an extended or flexed 'phantom' hand as ischemic anesthesia progressed (Inui et al. in J Physiol 589:5775-5784, 2011). Here, we examined what happened if the hand was held in the midposition before and during the anesthesia. Twenty heal...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3040-9
更新日期:2012-05-01 00:00:00
abstract::We investigated a double-label 2-DG protocol and method of analysis in which sequential injections of 3H- and 14C-2-DG were used to map brain metabolism during two distinct experimental treatments in the same animal. In initial studies, brain sections from rats given only 3H-2-DG or only 14C-2-DG were exposed on Ultro...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00270687
更新日期:1987-01-01 00:00:00
abstract::After several days of exposure to optically-imposed post-saccadic retinal slip, the saccades of normal monkeys acquire an exponential ocular drift. This drift is in the direction of the imposed image motion, and persists in the dark. It has been argued that these changes result from the operation of a visually mediate...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00340497
更新日期:1986-01-01 00:00:00
abstract::Perception of whether a given behavior is possible typically reflects a person's action capabilities even before the behavior is performed and even when the person has undergone recent changes to their action capabilities. Importantly, perception of affordances for a given behavior also reflects impending changes to a...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3104-x
更新日期:2012-06-01 00:00:00
abstract::Trajectories of goal-directed movements are less curved for movements over a surface (constrained) than for movements in empty space (unconstrained). To study whether this difference arises from feeling the surface slip across the skin or having to control the movements in a third dimension, we manipulated the availab...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-4030-x
更新日期:2014-11-01 00:00:00
abstract::The climbing fibres to the x and lateral c1 zones of the anterior lobe of the cerebellum arise as branches of common stem olivary axons. Anatomical studies have shown that the c1 zone receives its climbing fibres from the dorsal accessory olive (DAO). It has, therefore, been assumed that the x-zone also receives its c...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235868
更新日期:1985-01-01 00:00:00
abstract::The 2-deoxyglucose (2-DG) autoradiographic technique was used to map functional activity in the central auditory system of the mongolian gerbil, throughout the period of functional onset. Uptake of 2-DG during exposure to 105 dB SPL wide band noise (WBN) was compared to silence in adults and in neonates at 12, 14, 16 ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00239360
更新日期:1982-01-01 00:00:00
abstract::Using a declarative memory paradigm, the anatomical correlates of spatial location encoding and retrieval in the healthy human brain as reflected by BOLD fMRI were investigated. During encoding, subjects were instructed to view and keep in mind different locations of an object on a platform seen from different viewpoi...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0408-8
更新日期:2006-09-01 00:00:00
abstract::Electron microscopic examination of the monkey lateral geniculate nucleus, pars dorsalis (LGNd) reveals the occurrence of synaptic contacts between profiles belonging to interneurons (I-cells). Almost all combinations are observed, namely, axodendritic, dendrodendritic, dendrosomatic and somatodendritic, the most freq...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237322
更新日期:1976-05-10 00:00:00
abstract::For an understanding of how various degrees of altered use (training, disuse) affect the properties of skeletal muscles, it is important to know how much they are used normally. The main aim of the present project was to produce such background knowledge for hindlimb muscles of the cat. In four adult female cats, each...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/pl00005701
更新日期:1997-06-01 00:00:00
abstract::Recent morphological observations have suggested neurotransmitter specific degeneration of amongst others, the serotonergic system in the aged rat brain. However, morphological studies can only give a static picture of the events that take place over a period of several months. In the present study we used an experime...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00230689
更新日期:1989-01-01 00:00:00
abstract::The aim of the present study was to further investigate the contribution of primary muscle spindle feedback to proprioception and higher brain functions, such as movement trajectory recognition. For this purpose, complex illusory movements were evoked in subjects by applying patterns of muscle tendon vibration mimicki...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-0325-2
更新日期:2006-06-01 00:00:00
abstract::The mesencephalic dopamine (DA) cell system was examined in mice homozygous and heterozygous for the weaver (wv) gene and in wild-type controls to estimate the extent of cell losses associated with the genetically determined central DA deficiency observed in weaver homozygotes. Animals of the three genotypes (+/+, wv/...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248351
更新日期:1988-01-01 00:00:00
abstract::The task of sliding a nut from a rod has been used to study manual slowing in old age (Smith et al. in Neurology 53:1458-1461, 1999; Neurobiol Aging 26:883-890, 2005). In this experiment, we sought to determine if the age-related slowing in this task occurs with losses of motor precision, as indicated by the forces ex...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-2030-z
更新日期:2010-03-01 00:00:00
abstract::This study examines the process of learning to walk from a functional perspective. To move forward, one must generate and control propulsive forces. To achieve this, it is necessary to create and tune a distance between the centre of mass (CoM) and the centre of pressure (CoP) along the antero-posterior axis. We hypot...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4378-6
更新日期:2015-10-01 00:00:00
abstract::The cerebellum is known to participate in visually guided eye movements. The cerebellar uvula receives projections from pontine nuclei that have been implicated in visual motion processing and the generation of smooth pursuit. Single-unit and lesion studies were conducted to determine how the uvula might further proce...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00241368
更新日期:1996-06-01 00:00:00
abstract::It has been suggested that lagged and non-lagged cells in the cat dorsal lateral geniculate nucleus (LGN) represent state-dependent response modes of the same class of LGN cells. In two separate experiments with single-unit recording in the LGN of anaesthetized and paralysed adult cats, a lagged and a nonlagged X-cell...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF02259147
更新日期:1992-01-01 00:00:00
abstract::Integration of tactile afferent signals with motor commands is crucial for the performance of purposeful movements such as during manipulation of an object in the hand. To study the somatotopic organization of sensorimotor integration we applied electrical peripheral conditioning stimuli to a digit located near (homot...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050005
更新日期:2000-01-01 00:00:00
abstract::Single cells were recorded in layers A and A1 of the cat dorsal lateral geniculate nucleus (dLGN) with multibarrel micropipettes. Interocular inhibition ("binocular inhibition") was elicited by phase-reversing gratings presented monocularly to the nondominant eye. This inhibition was blocked by microiontophoretic appl...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00239516
更新日期:1986-01-01 00:00:00
abstract::Here, we demonstrate a systematic shift in the perceived location of a tactile stimulus on the arm toward where the eye is looking. Participants reported the perceived position of touches presented between the elbow and the wrist while maintaining eye positions at various eccentricities. The perceived location of the ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-1884-4
更新日期:2009-09-01 00:00:00
abstract::In visual cortex of normal adult rabbits, callosal projections are restricted to a 2 mm wide band at the area 17/18 border. In adult rabbits which are monocularly enucleated (ME) on the day of birth, the callosal zone extends 4 mm into the medial region of area 17 in the cortex ipsilateral to the remaining eye. In thi...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231662
更新日期:1992-01-01 00:00:00
abstract::Functional magnetic resonance imaging was used to explore the neural correlates of semantic judgments to Chinese characters. Adult participants were asked to indicate if character pairs were related in meaning that were arranged in a continuous variable according to association strength. This parametric manipulation a...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-1942-y
更新日期:2009-10-01 00:00:00
abstract::Multisensory integration is known to create a more robust and reliable perceptual representation of one's environment. Specifically, a congruent auditory input can make a visual stimulus more salient, consequently enhancing the visibility and detection of the visual target. However, it remains largely unknown whether ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4591-y
更新日期:2016-05-01 00:00:00
abstract::This investigation represents a first study dealing with the dimorphic differences of the main alpha-containing gamma-aminobutyric acid (GABA(A)) receptors in the brain of two distantly related mammals (hedgehog and rat). The labeling of these receptors in the presence of zolpidem (highly selective benzodiazepine agon...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002219900246
更新日期:2000-02-01 00:00:00