Respiratory excretion of hydrogen and methane in Italian subjects after ingestion of lactose and milk.

abstract：:To investigate the possible role of hepatitis C virus (HCV) in fulminant and subacute liver failure, we tested serum and liver of 13 patients undergoing orthotopic liver transplantation for the presence of HCV RNA. HCV RNA was detected in specimens from two out of eight patients negative for all viral markers with sus...

journal_title：European journal of clinical investigation

authors： Theilmann L,Solbach C,Toex U,Müller HM,Pfaff E,Otto G,Goeser T

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Cancer chemotherapy in humans based on metal complexes started at the clinical level in the late 1970s with the use of cisplatin, which forms intra-strand cross-links with DNA. METHODS:Two new platinum complexes of cis-geometry with the amino acids inosine (ino) and l-alanine (ala), Pt(ino)2Cl2 and cis-[Pt(...

journal_title：European journal of clinical investigation

authors： Charalabopoulos K,Karkabounas S,Ioachim E,Papalimneou V,Syrigos K,Evangelou A,Agnantis N,Hadjiliadis N

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Fungal infections are still a relevant challenge for clinicians involved in the cure of patients with cancer. We retrospectively reviewed charts of hospitalized patients with haematological malignancies (HMs), in which a documented fungaemia was diagnosed between January 2011 and December 2015 at 28 adult an...

journal_title：European journal of clinical investigation

authors： Criscuolo M,Marchesi F,Candoni A,Cattaneo C,Nosari A,Veggia B,Verga L,Fracchiolla N,Vianelli N,Del Principe MI,Picardi M,Tumbarello M,Aversa F,Busca A,Pagano L,SEIFEM Group (Sorveglianza Epidemiologica Infezioni nelle Emopa

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Portal endotoxaemia has been speculated to be crucially involved in the pathogenesis of chronic hepatic inflammation, which is highly associated with the development of type 2 diabetes mellitus. This study tests whether portal endotoxaemia is a pathogenic link between chronic subacute hepatic inflammation an...

journal_title：European journal of clinical investigation

authors： Hsieh PS,Chan JY,Shyu JF,Chen YT,Loh CH

更新日期：2008-09-01 00:00:00

abstract：:Washed cells, from ascitic fluid, which contained predominantly polymorphonuclear leucocytes from casein treated donor mice, induced accelerated amyloid formation in untreated syngeneic recipient animals. A similar transfer model, with lymph node cell suspension, was ineffective. Amyloidogenesis was completely blocked...

journal_title：European journal of clinical investigation

authors： Kedar I,Ravid M

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:Different time-concentration profiles of plasma insulin following insulin modification of a frequently sampled intravenous glucose-tolerance-test (FSIVGTT) were observed in a study investigating maternal metabolism and fetal macrosomia. We aimed to investigate whether these differences were related to the vo...

journal_title：European journal of clinical investigation

authors： Jolly MC,Hovorka R,Godsland I,Amin R,Lawrence N,Anyaoku V,Johnston D,Robinson S

更新日期：2003-08-01 00:00:00

abstract：:Fibromuscular dysplasia (FMD) is an idiopathic, segmental, non-atherosclerotic and non-inflammatory disease of the musculature of arterial walls, leading to stenosis of small and medium-sized arteries, mostly involving renal and cervical arteries. As a result of better and more systematic screening, it appears that in...

journal_title：European journal of clinical investigation

authors： Van der Niepen P,van Tussenbroek F,Devos H,Debing E,Di Monaco S,Goffette P,Astarci P,Persu A

更新日期：2018-11-01 00:00:00

abstract：:The effect of infusions of recombinant insulin-like growth factor-I (IGF-I) (34, 103 or 688 pmol min-1 kg-1), insulin (3.4, 10.3 or 68.8 pmol min-1 kg-1) or combined infusions (34 pmol IGF-I + 3.4 pmol min-1 kg-1 insulin or 103 pmol IGF-I + 3.4 pmol min-1 kg-1 insulin) on protein metabolism, using an infusion of [1-14...

journal_title：European journal of clinical investigation

authors： Umpleby AM,Shojaee-Moradie F,Thomason MJ,Kelly JM,Skottner A,Sonksen PH,Jones RH

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Insulin has several biological functions besides glycaemic control. We investigated and compared the effects of six different commercial insulins on adipocyte cell differentiation, the lipolytic activity of differentiated cells, and the expression levels of genes involved in adipogenesis and associated with ...

journal_title：European journal of clinical investigation

authors： García-Escobar E,Rodríguez-Pacheco F,Haro-Mora JJ,Gomez-Zumaquero JM,Rubio-Martín E,Gutierrez-Repiso C,Soriguer F,Rojo-Martínez G

更新日期：2011-09-01 00:00:00

abstract：:To determine the comparative value of serum Type III procollagen peptide (PIIIP) in paediatric and adult liver disease we have measured PIIIP in 201 healthy subjects (aged 1 day-77 years) and twenty-one children and five adults with chronic active hepatitis (CAH). Healthy children had significantly higher PIIIP levels...

journal_title：European journal of clinical investigation

authors： Trivedi P,Cheeseman P,Portmann B,Hegarty J,Mowat AP

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Recent data suggest that, among other factors, comorbidity may be an important prognostic variable in patients with myelodysplastic syndromes (MDS) who are eligible for haematopoietic stem cell transplantation (SCT). PATIENTS AND METHODS:We examined the overall survival (OS) and underlying risk factors in 4...

journal_title：European journal of clinical investigation

authors： Boehm A,Sperr WR,Leitner G,Worel N,Oehler L,Jaeger E,Mitterbauer M,Haas OA,Valent P,Kalhs P,Rabitsch W

更新日期：2008-12-01 00:00:00

abstract：:The relationship between serum levels of lipoprotein(a) Lp(a)) and the presence of chronic diabetic complications was studied in 194 patients with non-insulin-dependent diabetes mellitus (NIDDM; 75 males, 119 females; age 66 +/- 11 years; duration of diabetes, 11 (range 1-35) years). They were taking various treatment...

journal_title：European journal of clinical investigation

authors： Heesen BJ,Wolffenbuttel BH,Leurs PB,Sels JP,Menheere PP,Jäckle-Beckers SE,Nieuwenhuijzen Kruseman AC

更新日期：1993-09-01 00:00:00

abstract：:Quinidine is known to reduce the renal clearance of digoxin, but this effect does not completely explain the influence of quinidine on the total clearance of digoxin. We therefore studied the effect of quinidine administration on biliary clearance of digoxin in five patients with atrial fibrillation. Biliary clearance...

journal_title：European journal of clinical investigation

authors： Angelin B,Arvidsson A,Dahlqvist R,Hedman A,Schenck-Gustafsson K

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:The DALI low-density lipoprotein (LDL) apheresis system is the first whole-blood apheresis system in regular clinical use. DALI stands for direct adsorption of lipoproteins, which describes the basic principle of operation of this newly developed LDL apheresis procedure. METHODS:The selective removal of LDL...

journal_title：European journal of clinical investigation

authors： Dräger LJ,Julius U,Kraenzle K,Schaper J,Toepfer M,Zygan K,Otto V,Steinhagen-Thiessen E

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Nasal nitric oxide (nNO) values are reduced in patients with cystic fibrosis (CF). Humming during nNO measurement increases nNO values in healthy subjects. Nasal NO is reduced in patients with CF, sinus disease or nasal polyps. Humming nNO values have not been reported in CF patients yet. Our aim was to expl...

journal_title：European journal of clinical investigation

authors： Struben VM,Sewbalak WV,Wieringa MH,Mantingh CJ,van den Toorn LM,Bakker M,Feenstra L,de Jongste JC

更新日期：2007-02-01 00:00:00

abstract：:Transfusion-related morbidity is an emerging challenge in chronically transfused patients with low-risk myelodysplastic syndromes (MDS). In these patients, transfusion-induced iron overload may represent a leading medical problem. However, although iron-chelating drugs are available, little is known about optimal diag...

journal_title：European journal of clinical investigation

authors： Valent P,Krieger O,Stauder R,Wimazal F,Nösslinger T,Sperr WR,Sill H,Bettelheim P,Pfeilstöcker M

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Mortality from prostate cancer remains a significant problem with current treatment(s), with an expected 30 350 deaths from prostate cancer in 2005. Long-acting natriuretic peptide, vessel dilator, kaliuretic peptide and atrial natriuretic peptide have significant anticancer effects in breast and pancreatic ...

journal_title：European journal of clinical investigation

authors： Vesely BA,Alli AA,Song SJ,Gower WR Jr,Sanchez-Ramos J,Vesely DL

更新日期：2005-11-01 00:00:00

abstract：:The action of lecithin:cholesterol acyltransferase (LCAT) was studied on an abnormal lipoprotein (LP-X) rich in phosphatidylcholine and cholesterol from the plasma of patients with obstructive liver disease. 60 mg LP-X isolated free of other lipoproteins and subsequently labelled with 3H-cholesterol were incubated wit...

journal_title：European journal of clinical investigation

authors： Patsch JR,Soutar AK,Morrisett JD,Gotto AM Jr,Smith LC

更新日期：1977-06-01 00:00:00

abstract：:Time-dependent effects of insulin on the leg exchange of glucose, lactate, glycerol, free fatty acids (FFA) and amino acids were measured in relation to oxygen uptake (leg and whole body) and whole body glucose assimilation including oxidation. Seven healthy males (58 +/- 3 years of age) were investigated before opera...

journal_title：European journal of clinical investigation

authors： Lundgren F,Edén E,Arfvidsson B,Lundholm K

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Diverticular disease (DD) and irritable bowel syndrome (IBS) share a similar symptom pattern. However, comparative studies are flawed by different age at onset of symptoms. We aimed to verify whether clinical features distinguish DD from IBS. MATERIALS AND METHODS:Patients with DD or IBS, matched for age an...

journal_title：European journal of clinical investigation

authors： Cuomo R,Barbara G,Andreozzi P,Bassotti G,Casetti T,Grassini M,Ierardi E,Maconi G,Marchi S,Sarnelli G,Savarino V,Usai P,Vozzella L,Annibale B

更新日期：2013-11-01 00:00:00

abstract：:Bile acid kinetics and biliary lipid composition were determined in ten hypothyroid patients before and after treatment with L-thyroxine. Hypothyroid patients had normal synthesis rates of cholic acid and chenodeoxycholic acid. Hormone treatment, which lowered plasma cholesterol by about 35%, stimulated the formation ...

journal_title：European journal of clinical investigation

authors： Angelin B,Einarsson K,Leijd B

更新日期：1983-02-01 00:00:00

abstract：:To understand better impairment of glucose utilization in diabetics during a hyperosmolal state, in vitro models were established to evaluate the effects of hyperosmolality on basal glucose uptake as well as glucagon dependent glucose release by isolated hepatocytes. In these studies simulating a hyperglycaemic (40 mm...

journal_title：European journal of clinical investigation

authors： Komjati M,Kastner G,Waldhäusl W,Bratusch-Marrain P

更新日期：1989-04-01 00:00:00

abstract：:The effects of treating the anaemia of end-stage renal failure with erythropoietin were studied in nine dialysis patients. The increase in haemoglobin concentration (by 59% from 7.0 +/- 1.2 to 11.1 +/- 1.1 g dl-1) was associated with increases in exercise duration (by 41%) and maximum oxygen consumption (by 34%). Trea...

journal_title：European journal of clinical investigation

authors： Lewis NP,Macdougall IC,Willis N,Coles GA,Williams JD,Henderson AH

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Cancer is often caused by disturbance in the regulation and/or execution of programmed cell death (PCD, including apoptosis and autophagy). Our aim was to investigate these two pathways simultaneously in the same samples to understand further the pathological roles of PCDs in colorectal cancer. MATERIALS AN...

journal_title：European journal of clinical investigation

authors： Chang YT,Tseng HC,Huang CC,Chen YP,Chiang HC,Chou FP

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Intestinal commensal flora seems to be a requisite for both human and experimental intestinal inflammation. Our aim was to assess the immunological changes in the colon of IL-10(-/-) mice depending on the environmental conditions. MATERIALS AND METHODS:Twelve wild-type (WT) and 24 IL-10(-/-) 4-week-old mice...

journal_title：European journal of clinical investigation

authors： Pedrosa E,Lorén V,Cabré E,Doménech E,Ojanguren I,Gassull MA,Mañé J

更新日期：2011-10-01 00:00:00

abstract：:Pulmonary plasma kinetics of endogenous noradrenaline (NA) and tritium labelled L-noradrenaline (3H-NA) was studied in fifteen subjects during pulmonary arterial catheterization. Plasma NA concentration in femoral artery ranged from 0.5 to 8.2 nmol l-1, mean 2.3 nmol l-1, which was not significantly different from tha...

journal_title：European journal of clinical investigation

authors： Henriksen JH,Christensen NJ,Ring-Larsen H

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:In mutations of the low-density lipoprotein (LDL) receptor gene, the defect of internalization is caused by a mutation in the cytoplasmic domain of the receptor linked with exons 17 and 18, and the O-linked sugar domain linked with exon 15 has been speculated not to affect the function of the receptor. Here,...

journal_title：European journal of clinical investigation

authors： Tashiro J,Endo M,Bujo H,Shinomiya M,Morisaki N,Saito Y

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Renal cyclooxygenases (COX) produce the prostaglandins (PG) E2, I2 and thromboxane (TxA2), which interact with distinct G protein-coupled receptors. We investigated the expression of the three EP receptors EP2, EP3 and EP4 and the receptors for PGI2 (IP) and TxA2 (TP) in rats with passive Heymann nephritis (...

journal_title：European journal of clinical investigation

authors： Waldner C,Heise G,Schrör K,Heering P

更新日期：2003-11-01 00:00:00

abstract：:Infusion of ethanol (0.6 g/kg body wt) caused marked hypoglycaemia in subjects fasted for 36 h. Previous administration of the alcohol dehydrogenase (ADH) inhibitor 4-methylpyrazole (4-MP, 7 mg/kg body wt i.v.) strongly suppressed the ethanol-induced hypoglycaemia. The rate of ethanol elimination was 84.6 mg/kg per ho...

journal_title：European journal of clinical investigation

authors： Salaspuro MP,Pikkarainen P,Lindros K

更新日期：1977-12-01 00:00:00

abstract：:A haemolytically inactive alpha-mobile complement C8 component was identified by crossed immunoelectrophoresis in a 27-year-old male with recurrent meningococcal infections and absence of complement mediated serum haemolytic activity. The patient's serum/plasma contained no demonstrable normal C8. C8 inhibitor activit...

journal_title：European journal of clinical investigation

authors： Brandslund I,Teisner B,Strate M,Grunnet N,Svehag SE,Isager H,Wang P

更新日期：1983-04-01 00:00:00