Abstract:
:Using sequential extractions with buffers containing or not containing neutral detergent, two highly insoluble protein components were found in livers of 30-day-old rats. These compounds (molecular weights (MW) 52 900 and 33 200 respectively) were practically absent from livers of young rats (between 5 and 8 postnatal days). After two-third hepatectomy performed on 30-day-old rats followed by a 24 h recovery, the level of these compounds is drastically decreased (about 50%). Monospecific antibodies against these components were obtained. Using immunohistochemical techniques, these antigens were localized in the membranes (essentially plasma membranes and sometimes internal membranes) of sinusoidal cells of adult rat livers. After partial hepatectomy, these antigens are no more present in the sinusoidal cells of the regenerating parts of the liver.
journal_name
Exp Cell Resjournal_title
Experimental cell researchauthors
Zanetta JP,Bingen A,Dontenwill M,Vincendon Gdoi
10.1016/0014-4827(84)90197-6subject
Has Abstractpub_date
1984-12-01 00:00:00pages
371-80issue
2eissn
0014-4827issn
1090-2422journal_volume
155pub_type
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