Cancer, a disease of defective glucose metabolism.

abstract：:Lithium is a naturally occurring alkali metal, which living organisms ingest from dietary sources and which is also present in trace amounts in the human body. In much higher concentrations, lithium is effective as a medication for mania and mood swings including manic depressive disorders. Many studies have shown tha...

journal_title：Medical hypotheses

authors： Demling JH,Eglau MC,Autenrieth T

更新日期：2001-10-01 00:00:00

abstract：:Infection of the lymphatic system by Wuchereria bancrofti microfilaria is the most common cause of elephantiasis, a disease that affects over 100 million people. The nightly release of microfilaria into the circulation coincides with the feeding activity of its mosquito vector, a synchronization that is presumably an ...

journal_title：Medical hypotheses

authors： Sack RL

更新日期：2009-08-01 00:00:00

abstract：:Bovine serum albumin and human serum transferrin modified by the water soluble carbodiimides N-ethyl-N'-(3-dimethyl propylamino) carbodiimide (CDI) or N-ethyl-N'-(3-trimethyl propylammonium) carbodiimide (Me+CDI) to yield N-acylurea proteins bind pBR322 DNA reversibly showing electrostatic and non-electrostatic compon...

journal_title：Medical hypotheses

authors： Ariatti M,Hawtrey AO

更新日期：1987-09-01 00:00:00

abstract：:The physical interaction between the red blood cells and colloidal silica leads to hemolysis. We propose that the nature of the red-cell elimination as the result of this interaction is not random. As the negatively charged silica particles at the physiological conditions electrostatically react with the positive site...

journal_title：Medical hypotheses

authors： Gerashchenko BI,Gerashchenko II,Pantazis CG

更新日期：1996-07-01 00:00:00

abstract：:It is proposed that there is biological regulation of the low molecular weight antioxidant (LMWA) status of the body, and that these different antioxidants work in concert and in homeostasis as a system analogous to the regulation of acid-base status (pH). The theoretical design characteristics for such a system inclu...

journal_title：Medical hypotheses

authors： Berry EM,Kohen R

更新日期：1999-11-01 00:00:00

abstract：:Insufficient attention has been given to reports in the literature describing patients with symptomatic migraine who, in addition to, or instead of, the well-recognized zones of hypofusion, have zones of hyperperfusion, which can be interpreted as hypermetabolism due to neuronal activation. A new neural theory of migr...

journal_title：Medical hypotheses

authors： Eggers AE

更新日期：2001-03-01 00:00:00

abstract：:The resonator theory claims that light scattering by the melanin granules of the retinal pigment epithelium causes light to be reflected back through the outer segment of the cones, in a direction opposite that of the incident light. These two opposite directed wave motions may produce standing waves inside the cone o...

journal_title：Medical hypotheses

authors： Bülow N

更新日期：1992-02-01 00:00:00

abstract：:The etiology of focal distribution of atherosclerotic lesions has received much attention for many years. Current theories focus on mechanical factors such as low endothelial shear stress as an initiating factor for atherosclerosis formation. However, some evidences revealed that it could not be initiator of endotheli...

journal_title：Medical hypotheses

authors： Mehdizadeh A,Norouzpour A

更新日期：2009-12-01 00:00:00

abstract：:Einstein is often quoted to have said that without the bee, mankind would have but 4years to live. It is highly unlikely that he made this comment, which was even mentioned in a Lancet article on honey bees. However, the current vanishing of the bees can have serious consequences for human health, because 35% of the h...

journal_title：Medical hypotheses

authors： Stindl R,Stindl W Jr

更新日期：2010-10-01 00:00:00

abstract：:Schmorl's nodes (SNs) are common abnormalities in the human spine, which represent herniation of the nucleus pulposus of the intervertebral disc into the adjacent cartilaginous endplate of the vertebra. However, the principle mechanism of SNs is still not fully understood. And the relationship of SNs in the spine and ...

journal_title：Medical hypotheses

authors： Zhang N,Li FC,Huang YJ,Teng C,Chen WS

更新日期：2010-03-01 00:00:00

abstract：:In light of the progressive, pubertal increases in serum gonadotropin (FSH, LH) levels coinciding with the peak incidence of simple goiters; the common alpha subunits associated with the gonadotropins, TSH and hCG; the ability of LH and hCG to bind to thyroid TSH receptors and affect thyroid function; and, the probabl...

journal_title：Medical hypotheses

authors： DiNicola AF

更新日期：1983-04-01 00:00:00

abstract：:Medicine today is an extremely heterogeneous field of knowledge, based on clinical observations and action knowledge and on data from the biological, behavioral and social sciences. We hypothesize at first that medicine suffers from a disciplinary hyper-diversity compared to the level of conceptual interdisciplinary i...

journal_title：Medical hypotheses

authors： Tretter F,Löffler-Stastka H

更新日期：2019-12-01 00:00:00

abstract：:Homocysteinemia, first identified as a genetic disease in children in the 1960s, is associated with severe widespread atherosclerosis which causes death (in untreated cases) before the age of 10 years. Elevated blood homocysteine is now recognized as a risk factor for heart disease in the general population. The mecha...

journal_title：Medical hypotheses

authors： Toohey JI

更新日期：2001-02-01 00:00:00

abstract：:Sudden infant death syndrome (SIDS) is frequently associated with a mild infection, the incidence peaking during the third month of life. We hypothesize that the neonatal immaturity of both the acute febrile response and hypothalamus promote neonatal protection from SIDS. Vagal afferents modify the febrile response. V...

journal_title：Medical hypotheses

authors： Reid GM,Tervit H

更新日期：1999-06-01 00:00:00

abstract：:It is suggested that apart from aflatoxins, plant medicinal preparations containing active compounds imperatorin, dictamine, marmesin and heraclenin may be responsible for some human cancers in Nigeria and perhaps other parts of Africa. Therefore, in this paper, a hypothesis is put forward that these compounds or thei...

journal_title：Medical hypotheses

authors： Adekunle AA,Adekunle LV

更新日期：1983-07-01 00:00:00

abstract：:In addition to classical metastatic pathways, recently gastric cancer was described having an alternative route called "endoluminal exfoliation". Provisional analyses demonstrated, in fact, this kind of shedding is associated with several clinico-pathological features indicative of aggressive behavior and resulted to ...

journal_title：Medical hypotheses

authors： Virgilio E,Balducci G,Mercantini P,Giarnieri E,Giovagnoli MR,Montagnini M,Proietti A,D'Urso R,Cavallini M

更新日期：2018-05-01 00:00:00

abstract：:This paper describes a model which puts together three key elements of cancer theory: the analogies between embryogenesis and carcinogenesis, the role played in both processes by morphogens and related pathways, and the recently emerged paradigm of cancer stem cells. The model is called Epigenetic Tracking. Originally...

journal_title：Medical hypotheses

authors： Fontana A,Wróbel B

更新日期：2013-10-01 00:00:00

abstract：:Abdominal aortic aneurysms (AAAs) have traditionally been attributed to atherosclerosis, although there is increasing epidemiological, biochemical and genetic evidence that aneurysmal arterial disease is different from occlusive atherosclerosis. One of the most consistent biochemical findings in the aneurysmal aorta i...

journal_title：Medical hypotheses

authors： Norman PE,Wysocki SJ,Lamawansa MD

更新日期：1995-07-01 00:00:00

abstract：:The role of ozone on earth is controversial, as in the stratosphere it is protective against excessive ultra violet irradiation, and in the troposphere it is toxic for animals and plants. The effectiveness of ozone against pathogens is well recognized and ozone appears to be the best agent for sterilization of water. ...

journal_title：Medical hypotheses

authors： Bocci V

更新日期：1996-02-01 00:00:00

abstract：:Late follicular progesterone (P) elevation continues to complicate a significant part of assisted reproductive technologies (ART) cycles, despite the ardent employment of gonadotropin releasing hormone (GnRH) analogues. In women with good ovarian reserve, late follicular P elevation is believed to be the result of the...

journal_title：Medical hypotheses

authors： Younis JS

更新日期：2019-04-01 00:00:00

abstract：:Personality trait research has shown associations with many genes, prominently those of the catecholamine metabolism such as dopamine beta hydroxylase (DBH), catechol-O-methyltransferase (COMT), and monoamine oxidase A (MAOA). Because DBH gene is in linkage disequilibrium with ABO gene, there is reason to think that o...

journal_title：Medical hypotheses

authors： Hobgood DK

更新日期：2011-08-01 00:00:00

abstract：:Positive cancer patient outcomes, including increased time to recurrent events, have been associated with increased counts and function of natural killer (NK) cells. NK cell counts and function are elevated following acute exercise, and the generally accepted mechanism of increased recruitment suggests that binding of...

journal_title：Medical hypotheses

authors： Evans W

更新日期：2017-11-01 00:00:00

abstract：:Exercise induced bronchospasm (EIB) affects approximately 10% of normal individuals with higher prevalence rates among children, obese adults, and competitive athletes. Although hyperpnea with dry air is the best known cause, the problem is multifactorial with atopy, asthma and chlorine all playing established roles. ...

journal_title：Medical hypotheses

authors： Simkin PA,Snitily BK

更新日期：2015-11-01 00:00:00

abstract：:The contribution of various modes of transmission of SARS-CoV-2 has been the subject of recent intensive debate. The predominant route of the viral transmission is via exhaled droplets of different sizes which can be inhaled by nearby exposed individuals or deposited on peoples and surfaces. Touching contaminated surf...

journal_title：Medical hypotheses

authors： Przekwas A,Chen Z

更新日期：2020-11-01 00:00:00

abstract：:Late luteal phase dysphoric disorder is described as a classic biopsychosocial disorder resulting from complex interactions of biological, psychological, socioeconomic and cultural forces on women. To understand women suffering from the disorder, one must understand how the genetically designed female brain and body i...

journal_title：Medical hypotheses

authors： Severino SK

更新日期：1993-09-01 00:00:00

abstract：:Except for a few diseases of molecular mimicry such as rheumatic fever, post-streptococcal glomerulonephritis in children, and gluten-sensitive enteropathy, the cause of autoimmune diseases is unknown. Most autoimmune diseases are remitting-relapsing and the pathophysiology of either the initial attack or subsequent r...

journal_title：Medical hypotheses

authors： Eggers AE

更新日期：2013-05-01 00:00:00

abstract：:Sudden cardiac death prematurely claims the lives of some 7 million each year worldwide. It occurs primarily in patients with an underlying structural cardiac abnormality, and regardless of the type of the underlying pathology (heart failure, dilated and hypertrophic cardiomyopathies, myocardial infarction and aging),...

journal_title：Medical hypotheses

authors： Sovari AA,Morita N,Weiss JN,Karagueuzian HS

更新日期：2008-08-01 00:00:00

abstract：:This hypothesis would help to elevate safety in nanogold-therapy of some cancers. It has no previous record in published media and there is no existing protocol for what is expressed in this paper. The hypothesis makes some experimental recommendations for future research at the interface of nanotechnology and biologi...

journal_title：Medical hypotheses

authors： Bonjar LS

更新日期：2013-05-01 00:00:00

abstract：:Severe affective and behavioral dysregulation, labeled as severe mood dysregulation (SMD), is a widely spread phenomenon among adolescent psychiatric patients. This phenotype constitutes severe impairment across multiple settings, including various symptoms, such as non-episodic anger, mood instability, and hyperarous...

journal_title：Medical hypotheses

authors： Heiler S,Legenbauer T,Bogen T,Jensch T,Holtmann M

更新日期：2011-10-01 00:00:00

abstract：:Several hypotheses have been developed to interpret the progression of tubulointerstitial fibrosis (TF), including senescence, epithelial-mesenchymal transition, inflammation, chronic hypoxia, and reactive oxygen species. All of these hypotheses are based on persistent cell injury and localized cell death. Proliferati...

journal_title：Medical hypotheses

authors： Chen BC,Bai YH,Tang LL,Wang BQ,Liu B,Cai Y,Peng X,Yang YR,Zheng SL

更新日期：2014-06-01 00:00:00