Distribution of substance P and enkephalin-like immunoreactivity in the substantia nigra of rat, cat and monkey.

abstract：:Developing nigrostriatal axons and their perikarya have substantial quantities of dopamine (DA) before the axons reach their postsynaptic target. In order to investigate possible developmental effects of these stores of DA, we have depleted DA chronically during critical periods in the ontogeny of the nigrostriatal sy...

journal_title：Brain research bulletin

authors： Tennyson VM,Budininkas-Schoenebeck M,Gershon P

更新日期：1982-07-01 00:00:00

abstract：:The antinociceptive response of mice to the amino acid L-arginine (L-ARG) has been attributed to either an opioid mechanism or a non-opioid but nitric oxide (NO)-dependent mechanism. Earlier it was reported that the mechanism of nitrous oxide-induced antinociception involved opioid components and was also dependent on...

journal_title：Brain research bulletin

authors： Chung E,Burke B,Bieber AJ,Doss JC,Ohgami Y,Quock RM

更新日期：2006-07-31 00:00:00

abstract：:Growing interest in cholinergic neuronal systems has caused a resurgence of thiocholine histochemical studies. Reports from different laboratories refer to "modified" Koelle-Friedenwald procedures for the histochemical localization of acetylcholinesterase (AChE) but the modifications are seldom specified. A glance at ...

journal_title：Brain research bulletin

authors： van Ooteghem SA,Shipley MT

更新日期：1984-05-01 00:00:00

abstract：:Chronic cerebral hypofusion (CCH) after bilateral carotid artery occlusion (2VO) causes cognitive damage and neuronal degeneration in the cortex and hippocampal CA1 area, and influences the oxygen and glucose supply in the brain which often results in metabolic alterations and oxidative stress. AMP-activated protein k...

journal_title：Brain research bulletin

authors： Chen Y,Guo Z,Peng X,Xie W,Chen L,Tan Z

更新日期：2018-06-01 00:00:00

abstract：:Intra-arterial administration of papaverine has been revealed to cause an increase in the blood-brain tumor barrier (BTB) permeability. The exact mechanism of papaverine opening the BTB in chemotherapy of malignant cerebral tumors, however, has not been well described. We used a rat brain glioma (C6) model for studyin...

journal_title：Brain research bulletin

authors： Wang ZH,Xue YX,Liu YH

更新日期：2010-11-20 00:00:00

abstract：:Fluoro-Ruby (tetramethylrhodamine-dextran amine conjugate) has been shown recently to be an effective anterograde tracer readily visible in brain sections with fluorescence microscopy. We show in this study that further microscopic analysis of Fluoro-Ruby-labeled elements is feasible with a conventional immunoperoxida...

journal_title：Brain research bulletin

authors： Chang HT

更新日期：1993-01-01 00:00:00

abstract：:The effects of histamine H3-receptor antagonists, thioperamide, and clobenpropit on amygdaloid kindled seizures were investigated in rats. Both intracerebroventricular (i.c.v.) and intraperitoneal (i.p.) injections of H3-antagonists resulted in a dose-related inhibition of amygdaloid kindled seizures. An inhibition in...

journal_title：Brain research bulletin

authors： Kakinoki H,Ishizawa K,Fukunaga M,Fujii Y,Kamei C

更新日期：1998-07-15 00:00:00

abstract：:In this study, we examine the utility of computational modeling in understanding nervous system function. We start by examining the reasons for, and major approaches to, computational modeling. We then chose a modeling approach and applied different variations to understanding nucleus tractus solitarius (NTS) neuronal...

journal_title：Brain research bulletin

authors： Rogers RF,Rybak IA,Schwaber JS

更新日期：2000-01-15 00:00:00

abstract：:The olfactory bulbectomized (OBX) rat model of depression has been widely used in studies on the behavioral and neurochemical aspects of human depression. The objective of the present investigation was to assess open field (OF) activity and the brain regional 5-HT(1A) receptor densities of the sham operated (SHX) and ...

journal_title：Brain research bulletin

authors： Sato H,Skelin I,Debonnel G,Diksic M

更新日期：2008-03-28 00:00:00

abstract：:Excitatory amino acid transporters (EAATs) represent a group of high affinity glutamate transporters that are involved in the regulation of extracellular glutamate levels at glutamatergic synapses. EAAT proteins have been found on neurons as well as on glia cells where they act synergistically to remove the released g...

journal_title：Brain research bulletin

authors： Gesemann M,Maurer CM,Neuhauss SC

更新日期：2010-10-30 00:00:00

abstract：:We previously reported that systemic treatment with a noncompetitive antagonist affecting the NMDA subtype of excitatory amino acid (EAA) receptor, MK-801, inhibits photic induction of Fos-like immunoreactivity (Fos-lir) in the hamster suprachiasmatic nucleus (SCN). Because MK-801 blocks the Ca2+ channel associated wi...

journal_title：Brain research bulletin

authors： Abe H,Rusak B,Robertson HA

更新日期：1992-05-01 00:00:00

abstract：:Melanin was measured by a spectrophotofluorometric method in the brains of albino rats from birth to 20 months of age. The concentration of brain melanin increased from Day 1 until adult levels were reached at 1 month. Between 1 and 20 months of age no significant differences were found in brain melanin. Daily injecti...

journal_title：Brain research bulletin

authors： Kastin AJ,Kuzemchak B,Schally AV,Eggert MW Jr

更新日期：1979-11-01 00:00:00

abstract：:beta-Amyloid and related peptides are components of the neurofibrillary tangles found in the brains of patients with Alzheimer's disease and have been suggested to be directly involved in the pathophysiology of that condition. It is unclear whether the amyloid deposited in the brain arises from the peripheral circulat...

journal_title：Brain research bulletin

authors： Banks WA,Kastin AJ,Barrera CM,Maness LM

更新日期：1991-12-01 00:00:00

abstract：:The large neurons in the rat neostriatum consist of at least two morphologically distinct types in Golgi preparations: Type I large cells had smooth somata whereas type II large cells had somatic spines. In the present study, the ultrastructural morphology of the Golgi-stained large neostriatal neurons in the rat was ...

journal_title：Brain research bulletin

authors： Chang HT,Kitai ST

更新日期：1982-06-01 00:00:00

abstract：:Repeated intraventricular injection of the excitatory amino acids glutamate and aspartate for one hour produced morphologic changes in the hippocampus that were qualitatively identical to the acute and chronic changes seen in the brains of human epileptics and in experimental animals in which hippocampal seizure activ...

journal_title：Brain research bulletin

authors： Sloviter RS,Dempster DW

更新日期：1985-07-01 00:00:00

abstract：:Fibroblast growth factor 9 (FGF9) is a member of the fibroblast growth factor family and is widely expressed in the central nervous system (CNS). However, it is not clear how the working mechanism of FGF9 is involved in cerebellar development. To address this question, we deleted the Fgf9 gene specifically in GABAergi...

journal_title：Brain research bulletin

authors： Guo M,Chen H,Duan W,Li Z,Li Y,Ma Y,Xu X,Yi L,Bi Y,Liu Y,Zhang J,Li C

更新日期：2020-01-01 00:00:00

abstract：:Simple tandem repeats represent more than 1% of the human genome: occasionally they exhibit intergenerational expansibility and are associated with neuromuscular diseases. In transgenic mice the same sequences elicit similar symptoms, but do not expand. We have searched for di-, tri-, and tetra-repeats in the publishe...

journal_title：Brain research bulletin

authors： Astolfi P,Bellizzi D,Losso MA,Sgaramella V

更新日期：2001-10-01 00:00:00

abstract：:Normal human subjects made rapid extensions of the elbow from an initial position to visual targets at different angular distances (9 degrees-54 degrees). We recorded joint angle, acceleration, and surface electromyograms (EMGs) with a monopolar electrode from the triceps and the biceps brachii muscles. Both the agoni...

journal_title：Brain research bulletin

authors： Yamazaki Y,Suzuki M,Mano T

更新日期：1993-01-01 00:00:00

abstract：:Isolated, superfused bullfrog retinas were stimulated in such a manner as to allow examination of the dynamics of the shift in the stimulus-response curve that accompanies light adaptation of cone photoreceptors. Observed phenomena were highly temperature dependent with complex Arrhenius relationships, suggesting that...

journal_title：Brain research bulletin

authors： Haynes LW,Sillman AJ

更新日期：1987-05-01 00:00:00

abstract：:Sleep EEG in the sigma and delta frequency bands was subjected to spectral analysis in 8 normal young adults. In each subject, power density of sigma and delta oscillated reciprocally during NREM sleep, confirming an observation made initially with period/amplitude analysis. In REM sleep, power density for both freque...

journal_title：Brain research bulletin

authors： Uchida S,Maloney T,March JD,Azari R,Feinberg I

更新日期：1991-07-01 00:00:00

abstract：:Sporadic Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder affected by amyloid and vascular pathogenesis. Brain insulin resistance (BIR) has been suggested as one of the pathomechanisms of sporadic AD. We investigated how the amyloid and vascular pathogenesis of AD interacts with BIR. We examined...

journal_title：Brain research bulletin

authors： Choi BR,Seo JH,Back DB,Han JS,Choi DH,Kwon KJ,Shin CY,Lee J,Kim HY

更新日期：2020-05-01 00:00:00

abstract：:There is some experimental evidence that the pallial areas of a fish's brain are involved in distincted learning functions. Recently published data suggest that the medial pallium is essential for avoidance learning and the lateral pallium is crucial for spatial learning and is also involved in temporal aspects of the...

journal_title：Brain research bulletin

authors： Vargas JP,López JC,Portavella M

更新日期：2009-08-14 00:00:00

abstract：:The electroencephalographic (EEG) activity of the hippocampus was examined in adult freely moving rats that had had all of the neocortex, including the cingulate cortex and cingulum, removed at birth. Both the cholinergic and serotonergic forms of rhythmical slow activity (RSA or theta) were present in the dorsal hipp...

journal_title：Brain research bulletin

authors： Whishaw IQ,Dyck R,Kolb B

更新日期：1991-03-01 00:00:00

abstract：:The possible involvement of basal telencephalic structures in visually conditioned heart rate change (established by pairing light and foot-shock) was studied in 156 pigeons by evaluating conditioning performance following lesions of the septum or lobus parolfactorius. Extensive destruction of the septal complex had n...

journal_title：Brain research bulletin

authors： Cohen DH,Goff DM

更新日期：1978-07-01 00:00:00

abstract：:We studied the effects of estradiol (E2) and progesterone (P) on progesterone receptor (PR) isoforms gene expression in the brain of ovariectomised female and gonadectomised male rats by RT-PCR analysis. In female rats, the expression of both PR isoforms was induced by E2 and down-regulated by P in the hypothalamus, w...

journal_title：Brain research bulletin

authors： Guerra-Araiza C,Coyoy-Salgado A,Camacho-Arroyo I

更新日期：2002-10-30 00:00:00

abstract：:One of the important factors altering the degree of blood-brain barrier (BBB) disruption in cerebral ischemia is the anesthetic used. The phosphoinositide 3-kinase (PI3K)/Akt signaling pathway has been reported to be involved in modulating BBB permeability and in isoflurane induced neuroprotection. This study was perf...

journal_title：Brain research bulletin

authors： Chi OZ,Mellender SJ,Kiss GK,Liu X,Weiss HR

更新日期：2017-05-01 00:00:00

abstract：:Degeneration of substantia nigra dopaminergic neurons is a key pathological change of Parkinson's disease (PD), and its motor consequences have been widely recognized. Recently, mood disorders associated with PD have begun to attract a great deal of interest, however, their pathogenesis remains unclear. PD is associat...

journal_title：Brain research bulletin

authors： Luo XF,Zhang BL,Li JC,Yang YY,Sun YF,Zhao H

更新日期：2015-01-01 00:00:00

abstract：:Among the brain areas studied only pars distalis and pars intermedia are found to contain beta-lipotropin activating enzyme indicating the these may be the exclusive organs for a physiologically significant conversion of beta-lipotropin into beta-endorphin. beta-Endorphin inactivating enzyme is found to be rather unif...

journal_title：Brain research bulletin

authors： Kenessey A,Graf L

更新日期：1977-07-01 00:00:00

abstract：OBJECTIVE:Transcranial near-infrared stimulation (tNIRS) can penetrate the scalp and skull and can reach the superficial layers of the cerebral cortex. In this study, we evaluated whether an 820-nm tNIRS can modulate the excitability of the primary motor cortex (M1) as measured by transcranial magnetic stimulation (TMS...

journal_title：Brain research bulletin

authors： Song P,Han T,Lin H,Li S,Huang Q,Dai X,Wang R,Wang Y

更新日期：2020-02-01 00:00:00

abstract：:Glucokinase (GCK) may be involved in inflammatory pathological changes, while the P2X3 receptor in the stellate ganglia (SG) is related to diabetic cardiac autonomic neuropathy. In this study, we explored the relationship between the upregulated GCK in SG and diabetic cardiac sympathy. The expression and location of G...

journal_title：Brain research bulletin

authors： Xu X,Liu B,Yang J,Zou Y,Sun M,Li Z,Li L,Yang R,Zou L,Li G,Liu S,Li G,Liang S

更新日期：2020-12-01 00:00:00