Abstract:
:To identify cis-acting DNA elements involved in the activation of the alpha-fetoprotein gene during differentiation, modified copies of the gene were introduced into murine F9 embryonal carcinoma cells. The differentiation of the transformants to either parietal or visceral endoderm was accompanied by induction of the exogenous template in a manner qualitatively, but not quantitatively, identical to that of the endogenous alpha-fetoprotein gene.
journal_name
Naturejournal_title
Natureauthors
Scott RW,Vogt TF,Croke ME,Tilghman SMdoi
10.1038/310562a0subject
Has Abstractpub_date
1984-08-16 00:00:00pages
562-7issue
5978eissn
0028-0836issn
1476-4687journal_volume
310pub_type
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