Regulation of sugar transport in cultured diploid human skin fibroblasts.

abstract：:Neuropathic pain caused by somatosensory nervous system dysfunction is a serious public health problem. Some long noncoding RNAs (lncRNAs) can participate in physiological processes involved in neuropathic pain. However, the effects of lncRNA DGCR5 in neuropathic pain have not been explored. Therefore, in our current ...

journal_title：Journal of cellular physiology

authors： Peng C,Zhang C,Su Z,Lin D

更新日期：2019-05-01 00:00:00

abstract：:Transforming growth factor-beta (TGFbeta) controls expression of plasminogen activator inhibitor type 1 (PAI-1), which regulates degradation of extracellular matrix proteins in fibrotic diseases. The TGFbeta receptor-specific Smad 3 has been implicated in the PAI-1 expression. The mechanism by which non-Smad signaling...

journal_title：Journal of cellular physiology

authors： Das F,Ghosh-Choudhury N,Venkatesan B,Li X,Mahimainathan L,Choudhury GG

更新日期：2008-02-01 00:00:00

abstract：:This study was undertaken to gain more insight into the mechanism whereby TGF-beta influences the cell cycle progression of cultured rabbit articular chondrocytes. Using proliferating chondrocytes in fetal calf serum-containing medium, we have previously shown that TGF-beta induced a recruitment of cells at the end of...

journal_title：Journal of cellular physiology

authors： Vivien D,Galéra P,Lebrun E,Daireaux M,Loyau G,Pujol JP

更新日期：1992-02-01 00:00:00

abstract：:CHFR acts as a tumor suppressor gene, which is frequently inactivated caused by its promoter hypermethylation in various solid tumors. Although a recent study showed that CHFR hypermethylation was a frequent event in acute myeloid leukemia (AML) and correlated with adverse clinical outcome, herein, we found that CHFR ...

journal_title：Journal of cellular physiology

authors： Zhou JD,Zhang TJ,Li XX,Ma JC,Guo H,Wen XM,Yao DM,Zhang W,Lin J,Qian J

更新日期：2018-06-01 00:00:00

abstract：:Cigarettes contain various chemicals with the potential to influence metabolic health. Exposure to cigarette smoke causes a dysfunction in pancreatic β-cells and impairs insulin production. However, the mechanisms for cigarette smoke-induced reduction of insulin remain largely unclear. Data from 558 patients with diab...

journal_title：Journal of cellular physiology

authors： Sun Q,Xu H,Xue J,Yang Q,Chen C,Yang P,Han A,Tu Q,Lu J,Gao X,Xiang Q,Liu Q

更新日期：2018-11-01 00:00:00

abstract：:The p53 protein directly regulates the expression of the WAF1 (wild-type p53-activated fragment 1) protein which is a cyclin-dependent kinase inhibitor (CDK1). DNA damaging agents such as ionizing or UV radiation, and some chemical agents induce WAF1 in wild-type p53 containing cells, thereby halting cell cycle progre...

journal_title：Journal of cellular physiology

authors： Shiohara M,Akashi M,Gombart AF,Yang R,Koeffler HP

更新日期：1996-03-01 00:00:00

abstract：:Protein sorting through vesicular compartments is highly regulated to maintain the integrity and signaling of intracellular organelles in eukaryotic cells. Sorting Nexin-2 (SNX2) is involved in protein sorting in the trans-Golgi network, endosome, and/or lysosome compartments, with loss of function leading to defect i...

journal_title：Journal of cellular physiology

authors： Abdul-Ghani M,Hartman KL,Ngsee JK

更新日期：2005-07-01 00:00:00

abstract：:Human promyelocytic leukemia (HL-60) cells display a novel voltage-dependent outward current under voltage clamp. This current is present at low levels in the proliferative state and in granulocytes derived from HL-60 cells which were induced to differentiate with retinoic acid. It is elevated in macrophages derived f...

journal_title：Journal of cellular physiology

authors： Wieland SJ,Chou RH,Chen TA

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) have a severe vitamin D deficiency and increasing epidemiological data suggesting that this deficiency may play a role in overall morbidity and mortality associated with CKD. It is known that vitamin D regulates the immune system, however, in dialysis patients this ...

journal_title：Journal of cellular physiology

authors： Almeida ACSF,Siqueira MC,Bonan NB,Dambiski A,Bertuzzo G,Moreno-Amaral AN,Barreto FC

更新日期：2019-02-25 00:00:00

abstract：:Neuropathic pain (NP) may cause serious brain diseases, but the genes associated with the metabolic pathway and transcript factors of NP remain unclear. This study is aimed to identify the therapy target genes for NP and to investigate the metabolic pathways and transcript factors associated with NP. The differentiall...

journal_title：Journal of cellular physiology

authors： Yan XT,Xu Y,Cheng XL,He XH,Wang Y,Zheng WZ,Zhao Y,Chen H,Wang YL

更新日期：2019-05-01 00:00:00

abstract：:Heparin-binding epidermal growth factor-like growth factor (HB-EGF) mRNA and protein expression is induced by EGF in MCF-10A nontransformed and Ha-ras transfected human mammary epithelial cells. The anti-EGF receptor (EGFR) blocking monoclonal antibody (MAb) 225 and the EGFR tyrosine kinase inhibitor PD153035 were abl...

journal_title：Journal of cellular physiology

authors： Martínez-Lacaci I,De Santis M,Kannan S,Bianco C,Kim N,Wallace-Jones B,Wechselberger C,Ebert AD,Salomon DS

更新日期：2001-02-01 00:00:00

abstract：:We examined the role of superoxide in the increase in intracellular pH (pHi) of human histiocytic leukemia U937 cells treated with 4 beta-phorbol-12,13-didecanoate (4 beta-PDD) or serum. 4 beta-PDD or serum induced a rapid increase in pHi, and antioxidants such as superoxide dismutase (SOD), vitamin E, and butylated h...

journal_title：Journal of cellular physiology

authors： Shibanuma M,Kuroki T,Nose K

更新日期：1988-08-01 00:00:00

abstract：:At 37 degrees C, undifferentiated murine teratocarcinoma cells (PCC4) are resistant to infection with SV40 and Polyoma virus. When infection is carried out at 31 degrees C, these cells become fully susceptible to a variety of polyoma virus strains, including wt, ts-a, and hr-t; they also display an increased susceptib...

journal_title：Journal of cellular physiology

authors： Dandolo L,Vasseur M,Kress C,Aghion J,Blangy D

更新日期：1980-10-01 00:00:00

abstract：:When calcium is removed from culture medium, motility of cultured cells is decreased. The effect is rapid, reversible and pronounced. Decreased motility is observed with normal mouse Balb/c 3T3 cells, mouse L929 cells, rat kidney fibroblasts and chick embryo fibroblasts. The calcium dependence of movement can be obser...

journal_title：Journal of cellular physiology

authors： Moore L,Pastan I

更新日期：1979-10-01 00:00:00

abstract：:Previous studies demonstrated that overexpression of the type-1 insulin-like growth factor (IGF) receptor (IGF-1R) in skeletal myogenic cell lines increased proliferation and differentiation responses to IGF. However, it was unclear if such manipulations in primary, untransformed skeletal myogenic cells would result i...

journal_title：Journal of cellular physiology

authors： Quinn LS,Haugk KL

更新日期：1996-07-01 00:00:00

abstract：:The snRNAs are abundant and stable components of the interphase nucleus. Aqueous and non-aqueous cell fractionation demonstrate that the snRNAs appear transiently in the cytoplasm shortly after transcription, before returning permanently to the interphase nucleus. In pulse label and chase experiments, the newly synthe...

journal_title：Journal of cellular physiology

authors： Zieve GW

更新日期：1987-05-01 00:00:00

abstract：:Signal transduction of fibroblast growth factor (FGF) receptors is known to involve tyrosine phosphorylation of several substrates, including Grb2, phospholipase C-gamma, and phosphatidylinositol 3-kinase, whereas the role of G-proteins in FGF receptor signaling is controversial. In the present study we investigated t...

journal_title：Journal of cellular physiology

authors： Piiper A,Stryjek-Kaminska D,Gebhardt R,Zeuzem S

更新日期：1996-04-01 00:00:00

abstract：:Repetitive mechanical stimulation of cultured avian skeletal muscle increases the synthesis of prostaglandins (PG) E2 and F2 alpha which regulate protein turnover rates and muscle cell growth. These stretch-induced PG increases are reduced in low extracellular calcium medium and by specific phospholipase inhibitors. M...

journal_title：Journal of cellular physiology

authors： Vandenburgh HH,Shansky J,Karlisch P,Solerssi RL

更新日期：1993-04-01 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) remains the leading cause of cancer death worldwide. As a platinum-based chemotherapeutic drug, cisplatin has been used in the NSCLC treatment for over 30 years, and its effects are impaired by drug resistance. This study aimed to investigate the potential role of lncRNA-AC078883.3 i...

journal_title：Journal of cellular physiology

authors： Xing S,Qu Y,Li C,Huang A,Tong S,Wu C,Fan K

更新日期：2019-12-01 00:00:00

abstract：:Apoptosis is also known as programmed cell death. Apoptosis plays an essential role in maintaining normal tissue and cell physiology in multicellular organisms. Clearance of aberrant or pre-cancerous cells occurs through the induction of apoptosis. It has been reported that many tumors and tumor cell lines have dysfun...

journal_title：Journal of cellular physiology

authors： Holmes WF,Soprano DR,Soprano KJ

更新日期：2004-06-01 00:00:00

abstract：:Adult stem cell therapy is being used extensively to rejuvenate damaged tissue. One important tissue source to obtain these cells is adipose, which contains cells called adipose-derived stem cells (ADSCs). These cells have a great therapeutic potential not only for their multipotent properties as well as for immunomod...

journal_title：Journal of cellular physiology

authors： Muñoz MF,Argüelles S,Medina R,Cano M,Ayala A

更新日期：2019-08-01 00:00:00

abstract：:Differentiated embryo chondrocyte 1 (DEC1), a member of basic-helix-loop-helix transcription factor Bhlhe40, also called stimulated by retinoic acid 13, STRA13, plays an important role in the regulation of adipogenesis, tumorigenesis, peripheral circadian output, response to hypoxia, and development of metabolic syndr...

journal_title：Journal of cellular physiology

authors： Huang Y,Lai X,Hu L,Lei C,Lan X,Zhang C,Ma Y,Zheng L,Bai YY,Lin F,Chen H

更新日期：2018-12-01 00:00:00

abstract：:Cells are quite sensitive to a change of the extracellular pH and respond to it through detection of the H+/HCO3- level in extracellular fluid. However, little is known about molecular details induced by acidosis, such as intracellular pathways and gene expression. Here we describe properties of gene expression, prote...

journal_title：Journal of cellular physiology

authors： Shimokawa N,Kumaki I,Qiu CH,Ohmiya Y,Takayama K,Koibuchi N

更新日期：2005-10-01 00:00:00

abstract：:Chronic hyperglycemia and activation of receptor for advanced glycation end products (RAGE) are known risk factors for microvascular disease development in diabetic retinopathy. Thioredoxin-interacting protein (TXNIP), an endogenous inhibitor of antioxidant thioredoxin (TRX), plays a causative role in diabetes and its...

journal_title：Journal of cellular physiology

authors： Perrone L,Devi TS,Hosoya K,Terasaki T,Singh LP

更新日期：2009-10-01 00:00:00

abstract：:The poor prognosis of pancreatic cancer patients using currently available therapies mandates novel therapeutics that combine anti-neoplastic potency with toxicity-minimizing cancer specificity. Employing an overlapping pathway screen to identify genes exhibiting coordinated expression as a consequence of terminal cel...

journal_title：Journal of cellular physiology

authors： Chan I,Lebedeva IV,Su ZZ,Sarkar D,Valerie K,Fisher PB

更新日期：2008-05-01 00:00:00

abstract：:This study establishes a causal link between the limitation of myofibre transitions and modulation of calcineurin activity, during different exercise paradigms. We have designed a new swimming-based training protocol in order to draw a comparison between a high frequency and amplitude exercise (swimming) and low frequ...

journal_title：Journal of cellular physiology

authors： Grondard C,Biondi O,Pariset C,Lopes P,Deforges S,Lécolle S,Gaspera BD,Gallien CL,Chanoine C,Charbonnier F

更新日期：2008-01-01 00:00:00

abstract：:We have examined the transport of amino acids by the sodium-dependent "A" and "ASC" system in thymic- and splenic-derived lymphocytes from the Long-Evans rat. Lymphocytes derived from the thymus transport amino acids by both the "A" and "ASC" systems, whereas lymphocytes from the spleen transport amino acids by the "A...

journal_title：Journal of cellular physiology

authors： Wise WC

更新日期：1978-11-01 00:00:00

abstract：:Macrophages are heterogeneous and their phenotype and functions are regulated by the surrounding micro-environment. Macrophages commonly exist in two distinct subsets: 1) Classically activated or M1 macrophages, which are pro-inflammatory and polarized by lipopolysaccharide (LPS) either alone or in association with Th...

journal_title：Journal of cellular physiology

authors： Shapouri-Moghaddam A,Mohammadian S,Vazini H,Taghadosi M,Esmaeili SA,Mardani F,Seifi B,Mohammadi A,Afshari JT,Sahebkar A

更新日期：2018-09-01 00:00:00

abstract：:The development of acute pancreatitis (AP) is triggered by acinar events, but the subsequent extra-acinar events, particularly a distinct immune response, appear to determine its severity. Cytokines modulate this immune response and are derived not only from immunocytes but also from pancreatic acinar cells. We studie...

journal_title：Journal of cellular physiology

authors： Gallmeier E,Schäfer C,Moubarak P,Tietz A,Plössl I,Huss R,Göke B,Wagner AC

更新日期：2005-04-01 00:00:00

abstract：:Gastric cancer prognoses are persistently poor due to cancer's penchant to metastasize. As a crucial regulator of signal transducer and activator of transcription (STAT3) signaling, sirtuin 1's (SIRT1) function in gastric cancer has not been well understood. Here, we report upregulated expression of SIRT1 in tissues i...

journal_title：Journal of cellular physiology

authors： Zhang S,Yang Y,Huang S,Deng C,Zhou S,Yang J,Cao Y,Xu L,Yuan Y,Yang J,Chen G,Zhou L,Lv Y,Wang L,Zou X

更新日期：2019-09-01 00:00:00