Abstract:
:Tubercidin may be directly brominated by reaction with N-bromosuccinimide in DMF to give 5-bromotubercidin, a reversible inhibitor of RNA synthesis. When buffered with potassium acetate the major product is 6-bromotubercidin. 5,6-Dibromotubercidin is formed in minor amounts under both conditions. N-Chlorosuccinimide and tubercidin give 5-chlorotubercidin and 5,6-dichlorotubercidin.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Bergstrom DE,Brattesani AJdoi
10.1093/nar/8.24.6213subject
Has Abstractpub_date
1980-12-20 00:00:00pages
6213-9issue
24eissn
0305-1048issn
1362-4962journal_volume
8pub_type
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