Produciton and biological activity of patulin and citrinin from Penicillium expansum.

Abstract:

:Penicillium expansum isolated from meat and apples produced both patulin and citrinin. Toxin identity was confirmed by spectroscopic and physical methods. The mean lethal dose in chicken embryos was determined for toxins administered both singly and in various ratios. Data from simultaneous administration of mycotoxin combinations plotted as isobolograms showed and additive effect. Both toxins were teratogenic in chicken embryos.

journal_name

Appl Environ Microbiol

authors

Ciegler A,Vesonder RF,Jackson LK

doi

10.1128/AEM.33.4.1004-1006.1977

subject

Has Abstract

pub_date

1977-04-01 00:00:00

pages

1004-6

issue

4

eissn

0099-2240

issn

1098-5336

journal_volume

33

pub_type

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