Abstract：
:We investigated the possibility of decreased cellular immunity (C.I.) in a substantial group of atopic asthmatic patients with respiratory tract infections during autumn and winter. Two-hundred and ten atopic asthmatic patients were selected, and the following tests for cellular immunity were performed. Skin tests with 11 bacterial and fungal antigens. Normal average value of the skin reactions is 2.5 mm. E rosettes with sheep erythrocytes. Normal value for patients of this age is 60 +/- 8%. Immunoglobulins A, G and M and complement fractions C3 and C4 were determined by radial immunodiffusion. IgE was determined using PRIST (Phadebas, Pharmacia). IgE was elevated in all except two of the patients. IgG, IgA and IgM, C3 and C4 were normal. Twenty five of the 85 patients had some depression in cellular immunity (decreased E rosettes and/or decreased skin reactions). Patients with depressed cellular immunity were given 2.5 mg Levamisol three times a week for three months. Their progress was evaluated clinically and immunologically and a positive correlation was found between clinical improvement and increased C.I. in 18 of the 25 patients. We consider Levamisol to be useful in approximately 8.5% of all asthmatic patients.
journal_name
Allergol Immunopathol (Madr)journal_title
Allergologia et immunopathologiaauthors
Fabiani J,Greiding L,Mathov Esubject
Has Abstractpub_date
1979-09-01 00:00:00pages
345-50issue
5eissn
0301-0546issn
1578-1267journal_volume
7pub_type
杂志文章abstract：BACKGROUND:Angiotensin Converting Enzyme inhibitors (ACEi) may cause angioedema, with an incidence of 0.1 % to 1 %, which may be life-threatening. ACEi induce angioedema by increasing the levels of bradykinin. Angiotensin II receptor blockers (ATRB), have a pharmacological profile similar to ACEi. The polymorphism of t...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：2008-05-01 00:00:00
abstract：:A study on the presence of specific precipitins against tobacco antigens was done in a population of 361 healthy cigrette smokers and in a group of 60 healthy non-smokers. The tests were made by the gel diffusion technique of Ouchterlony using tobacco extract prepared by the Coca method. A positive precipitation react...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1977-11-01 00:00:00
abstract：OBJECTIVE/HYPOTHESIS:We systematically reviewed the associations between allergic rhinitis or allergy and otitis media with effusion, by reference to published data. STUDY DESIGN:A meta-analysis of case-controlled studies. DATA SOURCE:Five databases (Pubmed, Highwire, Medline, Wanfang, and China National Knowledge In...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,meta分析
doi：10.1016/j.aller.2016.03.004
更新日期：2017-01-01 00:00:00
abstract：:Since half of the fetal transplantation antigens are paternal in origen, the conceptus could be considered as a particular allogeneic graft not rejected by the mother. The reason for this particular kind of tolerance remains mostly unknown, and an enormous amount of experimental work, clinical observations and hypothe...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：BACKGROUND:The objective of this study was to evaluate safety and efficacy of Privigen®, a 10% intravenous immunoglobulin (IVIG), in a particular group of paediatric patients (highly sensitive to previous IVIG infusion) affected with Primary Immunodeficiencies (PID). MATERIAL AND METHODS:Patients (n=8) from 3 to 17 ye...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2012.10.006
更新日期：2014-03-01 00:00:00
abstract：:The etiological importance of the dietary factor as related to infantile bronchial asthma is not, at times, sufficiently taken into consideration. Nevertheless, many times foods or their components are capable of provoking asthmatic symptoms. A group of asthmatic children was studied with the goal of more throughly co...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：BACKGROUND:It is considered that farm areas protect young patients from allergy and asthma due to high exposure to endotoxins. AIM:To compare CD4+/CD25+ T-regulatory cells and forkhead transcription factor Foxp3 expression in asthmatic children allergic to house dust mites (HDM) living in rural and farm areas. MATERI...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2018.04.003
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Asthma is the most common chronic disease affecting children and adolescents (AD). We evaluated the prevalence of asthma and associated factors in adolescents living in a developing region in northeast Brazil using the ISAAC (International Study of Asthma and Allergies in Childhood) methodology. METHODS:Acc...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2014.05.006
更新日期：2015-09-01 00:00:00
abstract：:Thirteen patients with severe partially reversible chronic obstructive lung disease received long-term treatment with a sustained-release preparation of theophylline and a beta 2-agonist (terbutaline) alone and in combination. Combination therapy induced significantly greater bronchodilation than treatment with terbut...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1985-11-01 00:00:00
abstract：:Urticaria and angioedema are common diseases in children and adults. Approximately 15-25% of the population will have urticaria or angioedema at least once in their life-time. Urticaria is characterized as the appearance of erythematous, circumscribed, elevated, pruritic, edematous swelling of the upper dermal tissue....
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-03-01 00:00:00
abstract：BACKGROUND:Peripheral blood B cells include lymphocytes at various stages of differentiation, each with a specific function in the immune response. All these stages show variations in percentage and absolute number throughout human life. The numbers and proportions of B subpopulation are influenced by factors such as g...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2016.05.003
更新日期：2016-01-01 00:00:00
abstract：:Lumry described 6 patients who presented hypertrophic rhinosinusitis, positive nasal eosinophilia and intolerance to nonsteroidal antiinflammatory drugs, manifested exclusively with naso-ocular symptomatology. We present three patients with clinical manifestations of chronic rhinitis who had noticed before their first...
journal_title：Allergologia et immunopathologia
pub_type： 临床试验,杂志文章
doi：
更新日期：1986-03-01 00:00:00
abstract：BACKGROUND:Migrants from developing to Western countries tend to become more sensitised to host than to origin country allergens, although substantial changes in migration patterns have occurred in recent decades. METHODS:We investigated adult immigrants with respiratory allergy, first tested for allergic sensitisatio...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2014.07.007
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:Autosomal dominant hyper-IgE syndrome (AD-HIES) is a primary immunodeficiency mainly caused by mutations in STAT3, a signalling molecule implicated in the development of appropriate immune responses. We aimed to characterise the innate immune response in AD-HIES. METHODS:The frequency of innate immune cells...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2014.11.002
更新日期：2015-11-01 00:00:00
abstract：:In medical literature, there are many cases reported of anaphylaxis due to fruits, before or after allergic reactions to latex. We present two atopic patients, with allergy to latex (by clinical history, positive skin test and RAST). Both patients showed a positive skin test and RAST to fruits (banana, kiwi, avocado a...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:A retrospective study on 52,900 individuals tested in 177 Italian Medical Centres for AIDS and related syndromes is reported. The data confirm that I.V. drug users are the group at highest risk in Italy (46% were seropositive and more than one half of these presented PGL or ARC) and that the epidemic probably started ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Sera from 19 patients with hypersensitivity pneumonitis induced by avian antigens were studied in order to determine the presence of circulating autoantibodies. IgM and IgG rheumatoid factors were positive in 68% and 100% of the cases respectively. IgM-rheumatoid factor was detected with at least two methods, showing ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Atopic dermatitis (AD) is a multifaceted disease that involves a complex interplay between the skin and the immune system. The course of the disease depends strongly on the genetic background of the patient and on yet poorly-defined environmental factors. Changes in lifestyle could be behind the dramatic rise in the p...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2017.07.002
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Cloxacillin is a semisynthetic penicillin widely used in nonmethicillin resistant Staphylococcus aureus infections. Several hypersensitivity reactions to cloxacillin have been reported, although IgE-mediated allergic reactions to the drug are rare and there is little information about possible tolerance to o...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1157/13084226
更新日期：2006-01-01 00:00:00
abstract：:A total of 181 allergic patients were studied and classified according to the causal antigen, 92 patients were sensitized to the mixed grass pollen, 55 to house dust, 28 to Candida albicans, 31 patients with egg allergy and 25 with milk allergy. All of them presented strong positivity to anamnesis, intracutaneous test...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:Atopic dermatitis is a chronic pruritic dermatosis that requires individualized treatment. Recent studies have shown that low-dose oral treatment with cyclosporine A may be useful in more severe forms. We report our experience with two patients who had severe atopic dermatitis. Both had high IgE concentration and sati...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：:The Bordeles School of Le Coulant described in 1966, a contact dermatitis produced by "hepatics" of the Frullania genus. The hepatics together with the mosses and sphagnus form the group of Bryophytes. Only the hepatics with leaves or Jungermaniales have a capacity to cause sensitivity. They grow in dark colour plates...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1976-07-01 00:00:00
abstract：BACKGROUND:Lung involvement in rheumatologic disease in children has been described with low frequency. OBJECTIVE:To describe the lung function test and the radiological findings in a group of paediatric patients with rheumatologic diseases. METHODS:Descriptive study. Pulmonary function was evaluated with spirometry,...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2011.02.009
更新日期：2012-03-01 00:00:00
abstract：:The term food allergy refers to the immune reaction (mediated by IgE or otherwise) that develops in response to the ingestion of a concrete type of food. Among the different potential manifestations of an allergic reaction, those exclusively affecting the gastrointestinal system are described. In recent years, the stu...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/s0301-0546(09)70250-2
更新日期：2009-01-01 00:00:00
abstract：:House dust mites (HDM) are a major cause of allergic sensitization and airway disease. Technological advances in assays permit the measurement of major mite allergens in house dust samples more accurately. We compared the results of different methods in the assessment of exposure to domestic mites in sensitized patien...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1996-11-01 00:00:00
abstract：:It is suggested that increased reactivity in asthma is not limited to the bronchi but also exists in the mediator releasing system. We have previously observed that the basophils of atopic asthmatics are degranulated by polymyxin B in vitro. The present study attempts to relate this basophil degranulation to atopy. Th...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1985-09-01 00:00:00
abstract：BACKGROUND:Asthma morbidity and mortality have been increasing. Data of asthma and respiratory mortality rates in Brazil are scarse. METHODS:We studied asthma and respiratory disease mortality rates in the state of So Paulo (capital and country side) from 1970 to 1996, as its relation with sales of drugs usually used ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/s0301-0546(02)79084-8
更新日期：2002-01-01 00:00:00
abstract：:In normal individuals the 5/9 monoclonal antibody (5/9 MAb) recognizes a T-cell fraction that includes all T lymphocytes with inducer activities. Here, circulating 5/9+ and 5/9- T lymphocytes were isolated from tuberculim skin-positive subjects and the proliferative response induced by PPD was investigated. The result...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：
更新日期：1987-03-01 00:00:00
abstract：OBJECTIVE:To investigate whether the genetic variants of TGFB1, TLE4, MUC22 and IKZF3 are associated with the development of asthma in Chinese children. METHODS:572 adolescent asthma patients and 590 age-matched healthy controls were included in this study. A total of four SNPs were genotyped, including rs2241715 of T...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章
doi：10.1016/j.aller.2016.10.021
更新日期：2017-01-01 00:00:00
abstract：:Toll-like receptors (TLRs) are a family of transmembrane receptors that have been preserved throughout evolution and which selectively recognize a broad spectrum of microbial components and endogenous molecules released by injured tissue. Identification of these ligands by TLRs triggers signalling pathways which lead ...
journal_title：Allergologia et immunopathologia
pub_type： 杂志文章,评审
doi：10.1016/j.aller.2009.04.004
更新日期：2009-09-01 00:00:00
