Erosive intervertebral osteochondrosis in association with generalized osteoarthritis and chondroc alcinosis; anatomico-radiological study of a case.

abstract：:Antibodies to double-stranded DNA (anti-dsDNA, dsDNA-Ab) are frequently found in systemic lupus erythematosus (SLE), especially during active disease and differ with respect to immunoglobulin class and avidity. The detection of anti-dsDNA is one of the diagnostic criteria for SLE according to the American College of R...

journal_title：Zeitschrift fur Rheumatologie

authors： Wigand R,Gottschalk R,Falkenbach A,Matthias T,Kaltwasser JP,Hoelzer D

更新日期：1997-03-01 00:00:00

abstract：UNLABELLED:Influence of anti-rheumatic drugs on human lymphocytes, especially T and B cell membranes, was studies with D-penicillamine, aurothiomalate, dexamethasone, cyclophosphamide, mitomycin C and aspirin. METHOD:Peripheral blood obtained from five healthy individuals and lymphocytes were separated by centrifugati...

journal_title：Zeitschrift fur Rheumatologie

authors： Yoshino S,Ishiyama I

更新日期：1977-01-01 00:00:00

abstract：:The "German Society of Rheumatology" was founded in Bad Neuenahr in the Federal Republic of Germany In 1947. The society perceived itself as the successor to the "German Society for the Abatement of Rheumatism". The primary aim of the society was close cooperation with other German-speaking rheumatological societies i...

journal_title：Zeitschrift fur Rheumatologie

authors： Hewelt T

更新日期：2011-01-01 00:00:00

abstract：:D-penicillamine treatment of 50 patients with rheumatoid arthritis with negative ANF tests, was followed by means of protein disk electrophoresis of the urine. In the beginning the urine proteins were analysed every 4 weeks, later at intervals of 3 to 6 months. A glomerular proteinuria, caused by an immune-complex nep...

journal_title：Zeitschrift fur Rheumatologie

authors： Rautenstrauch H

更新日期：1977-11-01 00:00:00

abstract：:Conventional radiography, ultrasonography (US), magnetic resonance imaging (MRI), computed tomography, and scintigraphy are imaging techniques in use for rheumatoid arthritis (RA). Conventional radiography of the hands and the forefeet should be performed every 6 to 12 months in the first two years, and every 12 to 24...

journal_title：Zeitschrift fur Rheumatologie

authors： Kellner H,Schmidt W,Rau R

更新日期：2005-11-01 00:00:00

abstract：:Evaluation of the sensitivity and value of magnetic resonance imaging (MRI) findings and miniarthroscopic investigations (mini-/needle-arthroscopy = MA) of metacarpophalangeal (MCP) joints in patients with rheumatoid arthritis (RA). 30 patients with RA (21 female, 9 male), disease duration 2 months to 22 years and mea...

journal_title：Zeitschrift fur Rheumatologie

authors： Peters R,Ostendorf B,Scherer A,Becker A,Dann P,Merk H,Mödder U,Schneider M

更新日期：2002-04-01 00:00:00

abstract：:The treatment of rheumatic diseases with bioloics has significantly improved the prognosis of patients. Currently, there are 13 preparations available in Germany for the treatment of patients with inflammatory rheumatic diseases. These original preparations generally have-depending on the individual country-15 years o...

journal_title：Zeitschrift fur Rheumatologie

authors： Braun J,Lorenz HM,Müller-Ladner U,Schneider M,Schulze-Koops H,Specker C,Strangfeld A,Wagner U,Dörner T

更新日期：2018-02-01 00:00:00

abstract：:1436 young men were investigated clinically and radiologically for rheumatic sacro iliitis. In two men (1.4%) definite bilateral sacro iliitis was diagnosed. In 18 cases (12.5%) the signs were not sufficient to make a definite diagnosis. They were regarded as suspected iliitis. For comparison the cards of 6138 patient...

journal_title：Zeitschrift fur Rheumatologie

authors： Yenal O,Usman ON,Yassa K,Uyar A,Agbaba S

更新日期：1977-09-01 00:00:00

abstract：:Serum protein binding of naproxen is considerably reduced in patients with renal insufficiency. The hypothetical plasma concentration at time zero and the half life are not significantly altered in uremic patients in comparison with healthy subjects when the drug is given orally. This suggests an increased pharmacodyn...

journal_title：Zeitschrift fur Rheumatologie

authors： Held H

更新日期：1979-03-01 00:00:00

abstract：:Polyarteritis nodosa (PAN) is a necrotizing vasculitis of medium size arteries that may affect various organs. The clinical appearance is very variable. The most common manifestations are of the skin, the peripheral nervous system presenting as mononeuritis multiplex and the mesenteric and renal blood vessels due to t...

journal_title：Zeitschrift fur Rheumatologie

authors： Schirmer JH,Holl-Ulrich K,Moosig F

更新日期：2014-12-01 00:00:00

abstract：:Methotrexate (MTX) is a safe and well-tolerated drug for the treatment of rheumatic diseases, even if the strictest safety standards are considered. Initial apprehension as to severe pulmonary or hepatic side-effects has not been confirmed. The risk of infection is not elevated compared with other disease-modifying an...

journal_title：Zeitschrift fur Rheumatologie

authors： Keysser G

更新日期：2011-02-01 00:00:00

abstract：:Since 1978 a 63-year-old woman with rheumatoid arthritis received D-penicillamine (D-PA) in a daily dose of 250-500 mg (mean 300 mg/d). In 1982 the patient complained of diplopia for several days, the ophthalmological and neurological examinations three days later were normal. In July 1983 she developed a myasthenic s...

journal_title：Zeitschrift fur Rheumatologie

authors： Kolarz G,Maida EM

更新日期：1986-05-01 00:00:00

abstract：:The supernatant of peripheral blood monocytes, cultured with autologous sera from patients with rheumatoid arthritis, stimulates healthy human granulocytes to significantly elevated chemiluminescence (p = 0.05) compared with supernatants of monocytes from osteoarthritic patients or healthy volunteers. Cultures without...

journal_title：Zeitschrift fur Rheumatologie

authors： Meske S,Bänziger E

更新日期：1988-05-01 00:00:00

abstract：:The diagnosis of rheumatoid arthritis has been hampered by the lack of a truly disease-specific serologic marker. Thus, despite its moderate specificity rheumatoid factor (RF) is still the only established marker antibody for RA and among the diagnostic criteria of the American College of Rheumatology the only serolog...

journal_title：Zeitschrift fur Rheumatologie

authors： Steiner G,Smolen JS

更新日期：2002-12-01 00:00:00

abstract：:Eight human femoral heads, surgically removed from patients with the clinical diagnosis: coxarthrosis or necrosis, were examined. In six of these we found severe arthrosis combined with synovitis and pannus formation. The pannus appeared as granulation tissue or fibrous connective tissue covering the surface of the ca...

journal_title：Zeitschrift fur Rheumatologie

authors： Pataki A,Lothe K,Spycher MA,Rüttner JR,Cserhati MD

更新日期：1983-11-01 00:00:00

abstract：:Mainly due to the general demographic changes and decreasing mortality in rheumatic diseases based on therapeutic progress, the proportion of older patients treated by rheumatologists is growing. Drug treatment in the elderly, however, harbors certain risks including age-specific pharmacokinetic features and high rate...

journal_title：Zeitschrift fur Rheumatologie

authors： Krüger K,Strangfeld A,Kneitz C

更新日期：2014-04-01 00:00:00

abstract：:Twelve patients with osteoarthrosis were locally treated with Felbinac Gel (biphenyl acetic acid (BPAA) 3%) three times daily for 14 days (five patients), 28 days (six patients) or 42 days (one patient) before elective knee joint surgery. BPAA plasma concentrations as of the seventh day of treatment were steady at bet...

journal_title：Zeitschrift fur Rheumatologie

authors： Bolten W,Waldorf-Bolten E,Sarfert D,Lehmann W,Miehlke W

更新日期：1990-11-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) results from loss of immunological tolerance. Regulatory T‑cells (Treg) are major gatekeepers of peripheral tolerance by suppression of autoreactive lymphocytes. Defects in Treg function are therefore possible pathogenetic mechanisms of SLE. Despite this fact published work about num...

journal_title：Zeitschrift fur Rheumatologie

authors： Ohl K,Tenbrock K

更新日期：2016-04-01 00:00:00

abstract：:Systemic sclerosis (SSc) is a polymorphic and heterogenic systemic disorder with inflammation, fibrosis and vascular damage. Early diagnosis and classification may be difficult if disease expression is oligosymptomatic (undifferentiated), presenting with only Raynaud's phenomenon or limited scleroderma. Scleroderma sp...

journal_title：Zeitschrift fur Rheumatologie

authors： Genth E,Krieg T

更新日期：2006-07-01 00:00:00

abstract：:Patients with various kinds of intestinal illnesses sometimes suffer not only abdominal symptoms, but also joint involvement, leading to a reduction in quality of life. Diseases leading to inflammatory joint involvement such as inflammatory bowel disease, Whipple's disease or surgical intestinal bypass, are classified...

journal_title：Zeitschrift fur Rheumatologie

authors： Ronneberger M

更新日期：2009-06-01 00:00:00

abstract：:Autoimmune hemolysis is a rare complication of systemic rheumatic diseases. We report on a 68-year-old female patient with established, long-standing rheumatoid arthritis, who complained of progressive weakness and worsening of her arthralgia under therapy with leflunomide. Physical and laboratory examination revealed...

journal_title：Zeitschrift fur Rheumatologie

authors： Lehmann P,Hartung W,Ehrenstein B,Schölmerich J,Fleck M

更新日期：2010-08-01 00:00:00

abstract：UNLABELLED:The regulatory region of the corticotropin releasing hormone (CRH) is highly conserved and plays a crucial role in the response of the organism to stress. Release of CRH initiates a cascade of events leading to the release of cortisone and the regulation of inflammatory and immune events. OBJECTIVE:Since it...

journal_title：Zeitschrift fur Rheumatologie

authors： Baerwald CG,Mok CC,Tickly M,Lau CS,Wordsworth BP,Ollier B,Panayi GS,Lanchbury JS

更新日期：2000-02-01 00:00:00

abstract：:Certolizumab pegol is a new anti-TNF-alpha inhibitor which has been approved for the treatment of rheumatoid arthritis since October 2009. Due to the modification of the antibody fragment by the adherence of polyethylene glycol (PEG) a sufficient distribution in inflammatory tissue was found in animal experiments. In ...

journal_title：Zeitschrift fur Rheumatologie

authors： Schmeiser T,Müller-Ladner U

更新日期：2010-09-01 00:00:00

abstract：:Over the last ten years various biologics have been introduced in the therapy of rheumatic diseases. The most successful approach so far has been the inhibition of TNF alpha, which is able to suppress systemic inflammation in an unprecedented manner. However, the early observation of newly developed antinuclear antibo...

journal_title：Zeitschrift fur Rheumatologie

authors： Manger K,Manger B

更新日期：2003-06-01 00:00:00

abstract：:Arthrosis deformans is a common disease worldwide with a high prevalence among all ethnic groups. All joints may be affected and genetic factors influence the onset of the disease. The main symptoms include pain and increasing immobility over the course of the illness. Treatment in early stages is conservative. In the...

journal_title：Zeitschrift fur Rheumatologie

authors： Rehart S,Lehnert H

更新日期：2008-07-01 00:00:00

abstract：:Large data bases and the projects arising from them have led to a much improved understanding of systemic sclerosis over the last decade. Serology has developed further so that more autoantibodies are available for routine testing. Capillary microscopy has become standard and relevant progress has also been made in th...

journal_title：Zeitschrift fur Rheumatologie

authors： Aringer M,Müller-Ladner U,Burkhardt H,Distler JH,Distler O,Graninger WB,Günther C,Hunzelmann N,Kiener H,Sticherling M,Sunderkötter C,Walker UA,Riemekasten G

更新日期：2015-03-01 00:00:00

abstract：:T-Large Granular Lymphocyte (T-LGL) leukaemia is a rare clonal disease characterized by neutropenia and/or anaemia. Because of its strong association with rheumatoid arthritis (RA), T-LGL leukaemia is an important differential diagnosis to Felty's syndrome. This differentiation might be especially difficult since, in ...

journal_title：Zeitschrift fur Rheumatologie

authors： Moosig F,Schoch R,Kneba M

更新日期：2006-09-01 00:00:00

abstract：:In recent years the great progress in knowledge on bone cell biology has allowed identification of molecular structures that can be targeted with pinpoint precision (druggable targets). Osteoclasts are regulated via the RANK-RANK-ligand (RANKL) signaling pathway and osteoblasts via the Wnt signaling pathway, both of w...

journal_title：Zeitschrift fur Rheumatologie

authors： Knauerhase A,Willenberg HS

更新日期：2016-06-01 00:00:00

abstract：:Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by, among other things, spinal and extraspinal manifestations. Two studies on the prevalence and clinical significance of hyperostotic spurs and ectopic ossifications in the pelvic area are presented. Spinal DISH seems to be a risk factor for the develop...

journal_title：Zeitschrift fur Rheumatologie

authors： Fahrer H,Koch P,Barandun R,Gerber NJ

更新日期：1988-07-01 00:00:00

abstract：:Primary osteoarthritis (OA) of peripheral joints is a common disease mainly occurring after the age of 50. It is important to distinguish primary from secondary OA. Younger age at disease onset, rapid progression, unusual disease manifestations and co-morbidities are signs of secondary OA. This review outlines an impo...

journal_title：Zeitschrift fur Rheumatologie

authors： Zwerina J,Dallos T

更新日期：2010-05-01 00:00:00