Bone changes from prostaglandin therapy.

Abstract:

:Prostaglandin E therapy in infants causes periosteal elevation. Although the changes usually take 30-40 days to become visible, we have seen them as early as nine days. In 15 infants who had prostaglandin E therapy for over six days, three developed periosteal elevation. Three other cases are described in greater detail, with long-term follow-up in two in which the bone remodeled to normal. Gallium scan in one showed increased uptake in areas involved. The periosteal cloaking may mimic Caffey disease but the pattern of involvement is different, since the mandible, which is commonly affected in Caffey disease, is rarely involved in prostaglandin E therapy.

journal_name

Skeletal Radiol

journal_title

Skeletal radiology

authors

Poznanski AK,Fernbach SK,Berry TE

doi

10.1007/BF00361189

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

20-5

issue

1

eissn

0364-2348

issn

1432-2161

journal_volume

14

pub_type

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