Abstract:
PURPOSE:To prospectively compare the diagnostic accuracy of diffusion-weighted whole body imaging with background whole body signal suppression (DWIBS) with skeletal scintigraphy for the diagnosis and differentiation of skeletal lesions in patients suffering from prostate or breast cancer. MATERIAL AND METHODS:A diagnostic cohort of 36 patients was included in skeletal scintigraphy and 1.5 T DWIBS MRI. Based on morphology and signal intensity patterns, two readers each identified and classified independently, under blinded conditions, all lesions into three groups: (1) malignant, (2) unclear if malignant or benign and (3) benign. Finally, for the definition of the gold standard all available imaging techniques and follow-up over a minimum of 6 months were considered. RESULTS:Overall, 45 circumscribed bone metastases and 107 benign lesions were found. DWIBS performed significantly better in detecting malignant skeletal lesions in patients with more than 10 lesions (sensitivity: 0.97/0.91) compared to skeletal scintigraphy (sensitivity: 0.48/0.42). No statistical difference could be found between DWIBS (0.58/0.33) and skeletal scintigraphy (0.67/0.58) in the sensitivity values for malignant skeletal lesions in patients with less than 5 lesions. For benign lesions, scintigraphy scored best with a sensitivity of 0.93/0.87 compared to 0.20/0.13 for DWIBS. Interobserver agreement with Cohen's kappa coefficient was calculated as 0.784 in the case of scintigraphy and 0.663 for DWIBS. CONCLUSION:With respect to staging, in prostate and breast carcinoma, the DWIBS technique is not superior to skeletal scintigraphy, but ranks equally. However, in the cases with many bone lesions, markedly more metastases could be discovered using the DWIBS technique than skeletal scintigraphy.
journal_name
Skeletal Radioljournal_title
Skeletal radiologyauthors
Gutzeit A,Doert A,Froehlich JM,Eckhardt BP,Meili A,Scherr P,Schmid DT,Graf N,von Weymarn CA,Willemse EM,Binkert CAdoi
10.1007/s00256-009-0789-4subject
Has Abstractpub_date
2010-04-01 00:00:00pages
333-43issue
4eissn
0364-2348issn
1432-2161journal_volume
39pub_type
杂志文章abstract::Early onset sarcoidosis is a granulomatous disease which is characterized by synovitis, polyarthritis, skin and eye involvement. We report the skeletal features of one patient with a family history and clinical symptoms suggestive of early onset sarcoidosis (EOS) which was confirmed by skin biopsy. Radiographs reveal ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-007-0315-5
更新日期:2007-09-01 00:00:00
abstract::We examined seven ankles with an accessory soleus muscle to determine if the magnetic resonance (MR) imaging features were sufficient to allow accurate diagnosis of this anomalous muscle. We believe that the diagnosis of an accessory soleus muscle is unequivocal with MR imaging on the basis of morphology and signal in...
journal_title:Skeletal radiology
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abstract::The objective of this article was to offer a better characterization of the typical clinical presentation, radiologic findings, histology, treatment approaches, and differential diagnosis of cystic angiomatosis, a rare condition of which previous reports have been confusing because of unclear diagnostic criteria, diff...
journal_title:Skeletal radiology
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doi:10.1007/s002560050082
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abstract::Three cases of calcific tendinitis occurring at an unusual site (vastus lateralis tendon) are described. Findings on conventional radiography and computed tomography together with the clinical history are characteristic for this disorder and reflect its natural evolution. The actual role of magnetic resonance imaging ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00243716
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To examine the effect of strenuous exercise on the magnetic resonance imaging (MRI) characteristics of the rotator cuff tendon. A second objective was to define an optimal time to image the rotator cuff and possibly eliminate exercise-induced false positives. DESIGN AND PATIENTS:Five male subjects from 24 to...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050171
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:To investigate the advantages of using tomosynthesis (TS) compared to radiographs in the detection, characterization, and follow-up of bisphosphonate-related atypical femur fractures (BP-AFF). SUBJECTS AND METHODS:Eight patients were identified retrospectively who underwent TS for radiographic findings suspi...
journal_title:Skeletal radiology
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doi:10.1007/s00256-016-2342-6
更新日期:2016-05-01 00:00:00
abstract::Nodular fasciitis is a benign rapidly proliferating fibrous tumor that is common in adults but relatively uncommon in children. When present in children, nodular fasciitis is typically subcutaneous in location and involves the head and neck. We present a case of intramuscular nodular fasciitis involving the rectus abd...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-012-1498-y
更新日期:2013-01-01 00:00:00
abstract::Shoulder arthroplasty is performed with increasing frequency, and osteoarthritis is the most common indication for this procedure. However, the glenoid side of the joint is widely recognized as a limiting factor in the long-term durability of shoulder replacement, and osteoarthritis leads to characteristic bony change...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-020-03647-x
更新日期:2020-10-23 00:00:00
abstract::Femoroacetabular impingement syndrome (FAI) is a pathologic entity which can lead to chronic symptoms of pain, reduced range of motion in flexion and internal rotation, and has been shown to correlate with degenerative arthritis of the hip. History, physical examination, and supportive radiographic findings such as ev...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-005-0932-9
更新日期:2005-11-01 00:00:00
abstract::Handigodu disease is a new syndrome of familial spondyloepi(meta)physeal dysplasia. It is inherited as an autosomal dominant trait. The disease is prevalent in a localised area of South India. On the basis of detailed clinical, anthropometric and radiological investigations of 234 affected individuals, it has been obs...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:
更新日期:1994-11-01 00:00:00
abstract::Chondroblastoma is a benign bone tumor that typically arises in the epiphysis of a long bone. However, when it occurs in non-epiphyseal location in flat bones, it may create a diagnostic problem. We describe such a case of chondroblastoma arising in the iliac bone. A 29-year-old man was incidentally found to have a bo...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-009-0833-4
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To describe the normal chronological radiographic appearances of the calcium sulphate-calcium phosphate (CaSO(4)/CaPO(4)) synthetic graft material following bone tumour resection during the processes of graft resorption and new bone incorporation into the post-resection defect. MATERIALS AND METHODS:Retrospe...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-010-1037-7
更新日期:2011-05-01 00:00:00
abstract::An unusual case of symptomatic thoracic vertebral hemangioma involving two contiguous vertebrae but confined to the posterior elements is presented. The lesion displaced and compressed the cord. The diagnosis was not considered prior to biopsy. There was uncontrolled bleeding at biopsy. Only partial surgical resection...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050359
更新日期:1998-03-01 00:00:00
abstract::Myositis ossificans (MO) is a benign soft tissue lesion with non-neoplastic heterotopic bone formation. MO in the intermediate and mature stages can be easily diagnosed if characteristic imaging findings such as a peripheral zonal pattern of ossification with variable thickness is observed. However, it is difficult to...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-016-2441-4
更新日期:2016-10-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-010-0934-0
更新日期:2010-11-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-016-2330-x
更新日期:2016-05-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-018-2876-x
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVE:To determine the accessibility of the coracohumeral ligament (CHL) by ultrasound (US) and to determine CHL thickness in adhesive capsulitis of the shoulder. DESIGN AND PATIENTS:US examinations were carried out in 498 consecutive shoulders of 306 individuals (194 women and 112 men), mean age 47.4 years (range...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-006-0136-y
更新日期:2006-09-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF02569405
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journal_title:Skeletal radiology
pub_type: 临床试验,杂志文章
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journal_title:Skeletal radiology
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更新日期:2014-11-01 00:00:00
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更新日期:1996-04-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-018-3016-3
更新日期:2019-02-01 00:00:00
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journal_title:Skeletal radiology
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更新日期:2016-12-01 00:00:00
abstract::Pseudoaneurysms of the dorsalis pedis artery are rare complications following arthroscopic surgery. This manuscript reports a case of an intra-articular pseudoaneurysm presenting nearly 5 months following an arthroscopic Broström procedure. The rarity of this complication and the patient's unusual clinical presentatio...
journal_title:Skeletal radiology
pub_type: 杂志文章
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更新日期:2019-03-01 00:00:00
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doi:10.1007/s00256-016-2549-6
更新日期:2017-02-01 00:00:00
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pub_type: 临床试验,杂志文章
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abstract::A rare case of chondroblastoma arising from the temporal bone that occurred in a 60-year-old woman is reported. The tumor appeared well demarcated and osteolytic on the radiographs. CT scan clearly depicted marginal and central calcification in the tumor. MR imaging demonstrated two components in the tumor: a solid co...
journal_title:Skeletal radiology
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更新日期:2001-12-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-015-2290-6
更新日期:2016-02-01 00:00:00