Abstract:
OBJECTIVE:We demonstrate the clinical use of an MR angiography sequence performed with sparse k-space sampling (MRA), as a method for dynamic contrast-enhanced (DCE)-MRI, and apply it to the assessment of sarcomas for treatment response. MATERIALS AND METHODS:Three subjects with sarcomas (2 with osteosarcoma, 1 with high-grade soft tissue sarcomas) underwent MRI after neoadjuvant therapy/prior to surgery, with conventional MRI (T1-weighted, fluid-sensitive, static post-contrast T1-weighted sequences) and DCE-MRI (MRA, time resolution = 7-10 s, TR/TE 2.4/0.9 ms, FOV 40 cm(2)). Images were reviewed by two observers in consensus who recorded image quality (1 = diagnostic, no significant artifacts, 2 = diagnostic, <25 % artifacts, 3 = nondiagnostic) and contrast enhancement characteristics by static MRI (presence/absence of contrast enhancement, percentage of enhancement) and DCE-MRI (presence/absence of arterial enhancement with time-intensity curves). Results were compared with histological response (defined as <5 % viable tumor [soft tissue sarcoma] or <10 % [bone sarcoma] following resection). RESULTS:Diagnostic quality for all conventional and DCE-MRI sequences was rated as 1. In 2 of the 3 sarcomas, there was good histological response (≤5 % viable tumor); in 1 there was poor response (50 % viable tumor). By static post-contrast T1-weighted sequences, there was enhancement in all sarcomas, regardless of response (up to >75 % with good response, >75 % with poor response). DCE-MRI findings were concordant with histological response (arterial enhancement with poor response, no arterial enhancement with good response). CONCLUSION:Unlike conventional DCE-MRI sequences, an MRA sequence with sparse k-space sampling is easily integrated into a routine musculoskeletal tumor MRI protocol, with high diagnostic quality. In this preliminary work, tumor enhancement characteristics by DCE-MRI were used to assess treatment response.
journal_name
Skeletal Radioljournal_title
Skeletal radiologyauthors
Fayad LM,Mugera C,Soldatos T,Flammang A,del Grande Fdoi
10.1007/s00256-013-1604-9subject
Has Abstractpub_date
2013-07-01 00:00:00pages
993-1000issue
7eissn
0364-2348issn
1432-2161journal_volume
42pub_type
杂志文章abstract::We report the development of isolated lower extremity metastases, in a child, 9 years after her initial diagnosis and treatment of bilateral infantile retinoblastomas. The radiographic, scintigraphic, computed tomographic, and magnetic resonance imaging findings are discussed. The dominant metastatic focus was blastic...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-005-0916-9
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:To review the imaging findings, age and gender distribution of chondroblastoma of the hands and feet. DESIGN AND PATIENTS:Twenty-five cases of pathologically proven chondroblastoma of the hands and feet were reviewed. Available imaging modalities included radiographs (n=24), CT (n=3), MRI (n=5), and radionuc...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-004-0762-1
更新日期:2004-10-01 00:00:00
abstract::The nasal septum is a particularly rare site of origin of chondrosarcoma. Cranial base invasion may be at hand, with such lesions making complete tumor removal difficult. MRI techniques allow precise definition of tumor extent. In the described case, CT and Dynamic MR imaging were performed in a case of chondrosarcoma...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-002-0535-7
更新日期:2002-09-01 00:00:00
abstract::With the growing number of orthopedic reconstructive spinal procedures, the use of bone grafting has steadily increased in the past decade. An understanding of the biology of bone grafting is essential for both the clinician and radiologist. Despite the advent of computed tomography and magnetic resonance imaging, con...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00241813
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:Since the thickness of cartilage is an important indicator of the status, progression and response to therapy of articular disorders, assessment of it is desirable. This study was undertaken to assess the accuracy, precision, and reliability of magnetic resonance (MR) measurements of articular cartilage. MET...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00941240
更新日期:1995-08-01 00:00:00
abstract::The cervical spine is the second most common location for manifestation of rheumatoid arthritis (RA). Symptoms are typically related to involvement of the craniocervical junction. Unfortunately, conventional radiographic examination is often unable to demonstrate that RA is the cause of such symptoms. Magnetic resonan...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00193087
更新日期:1990-01-01 00:00:00
abstract::COVID-19 has presented with a variety of manifestations including peripheral neurological symptoms. The most commonly associated peripheral neuropathies described with COVID-19 are Guillain-Barre syndrome and its variants as well as critical illness polyneuropathy. We report in this paper the distinct MRI findings of ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-021-03721-y
更新日期:2021-01-31 00:00:00
abstract::This 50-year-old woman presented with progressive pain in the left thigh. Radiographs showed a 9 x 6 cm soft-tissue mass located at the lateral border of the left femur. Magnetic resonance (MR) examination showed an eccentric, nonhomogeneous, soft-tissue mass abutting the femur. The preoperative differential diagnosis...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00190994
更新日期:1992-01-01 00:00:00
abstract::A syndrome of hyperostosis of the thoracic wall, nonspecific signs of inflammatory disease, and palmar and plantar pustulosis is described in eight patients (Table 1). Seven had intersternocostoclavicular ossification, and one had chronic recurrent multifocal osteomyelitis. This complex of findings has been called "pu...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00366761
更新日期:1989-01-01 00:00:00
abstract::Hibernoma is a benign adipose tumour that contains foetal brown fat cells. We report a case of hibernoma arising in the left ischium of a 65-year-old female with a past history of ovarian carcinoma. The patient presented with a relatively short history of left sacral/hip pain. Radiologically, the lesion, which was lar...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-016-2460-1
更新日期:2016-11-01 00:00:00
abstract::We report on a 9-year-old boy with metachronous aneurysmal bone cysts involving the tibia and pubis respectively. The patient has been clinically and radiographically followed for 3 years. ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050288
更新日期:1997-09-01 00:00:00
abstract:OBJECTIVE:The flexor digitorum accessorius longus muscle (FDAL), an anomalous muscle about the ankle, has recently been implicated in tarsal tunnel syndrome. The purpose of this study is to document the prevalence of the FDAL, its MR appearance and its relation to the neurovascular bundle in the tarsal tunnel. DESIGN ...
journal_title:Skeletal radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s002560050489
更新日期:1999-03-01 00:00:00
abstract::A 31-year-old woman presented with painful swelling in the right paravertebral region that had been present for 2 years. Radiography and CT revealed an area of increased density due to multiple calcifications localized at the fourth lumbar vertebra. Histological examination revealed that the lesion consisted of nodule...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050403
更新日期:1998-07-01 00:00:00
abstract::The objective of this article was to offer a better characterization of the typical clinical presentation, radiologic findings, histology, treatment approaches, and differential diagnosis of cystic angiomatosis, a rare condition of which previous reports have been confusing because of unclear diagnostic criteria, diff...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s002560050082
更新日期:1996-04-01 00:00:00
abstract::We evaluated the relative contribution of plain radiographs and computed tomography to the assessment of fracture healing under experimental circumstances. In 15 sheep, we performed midshaft femoral osteotomies and internal fixation of the resultant segmental fractures. Radiographs were obtained preoperatively and imm...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00355070
更新日期:1986-01-01 00:00:00
abstract::Spindle cell hemangioendothelioma occurring in skeletal muscle is extremely rare. No reported studies have performed an imaging evaluation of intramuscular spindle cell hemangioendothelioma. We report on such a tumor arising in an unusual site, the right extensor digiti minimi, in a 46-year-old woman. An en bloc resec...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050551
更新日期:1999-08-01 00:00:00
abstract:OBJECTIVE:To determine if a statistical association exists between abnormalities in one ankle tendon group (i.e., peroneal, medial flexor, or Achilles) and those in another. MATERIALS AND METHODS:A retrospective analysis of 1.5-T and 3-T MR ankle examinations in 100 patients conducted between November 1, 2011 and Apri...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-013-1650-3
更新日期:2013-10-01 00:00:00
abstract::We report on a 50-year-old man who suffered from chronic lumbago. CT and MRI revealed a paravertebral tumor mass growing through the neural foramen of lumbar vertebrae 1/2. Signal features on MRI and contrast medium enhancement characteristics were not diagnostically specific. After biopsy a glomus tumor of uncertain ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-004-0868-5
更新日期:2005-02-01 00:00:00
abstract::We report a unique case of mediastinal paravertebral chordoma without bone destruction in a 47-year-old Japanese woman. She was admitted to hospital after a tumor was incidentally detected on a chest radiograph. The tumor was located in the paravertebral region of the mediastinum and did not show any destruction of th...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-012-1493-3
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVE:The present study aims to provide orientation for clinicians and radiologists to recognize the most prevalent findings leading to diagnosis in mucolipidosis from a description of the natural history of five Brazilian cases. MATERIALS AND METHODS:We conducted an observational and retrospective study of five p...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-019-3159-x
更新日期:2019-08-01 00:00:00
abstract::We report on three boys suffering from achondroplasia concurrent with enchondromatosis-like metaphyseal changes. Two boys who were examined by molecular analysis harbored a mutation of FGFR3, which occurs in most achondroplastic individuals. Given the prevalence of achondroplasia and enchondromatosis, the metaphyseal ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-006-0161-x
更新日期:2007-06-01 00:00:00
abstract::Computed tomography is increasingly utilized for the evaluation of scaphoid fracture, nonunion, and deformity. We have developed a new technique of positioning patients while performing longitudinal computed tomography of the scaphoid. With the wrist positioned in radial deviation and neutral flexion, greater patient ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00198413
更新日期:1995-05-01 00:00:00
abstract::A case of polymyositis and localized vasculitis presenting as a muscular pseudotumor of a lower extremity and periostitis several years after the onset of symptoms was reported and the MRI characteristics were described. This imaging modality demonstrated muscle signal abnormalities in several muscle groups and was us...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/BF00223096
更新日期:1994-10-01 00:00:00
abstract:AIM:The aim of the study is to assess the feasibility of whole-body low-dose computed tomography (WBLDCT) in the diagnosis and staging of multiple myeloma and compare to skeletal survey (SS), using bone marrow biopsy and whole-body magnetic resonance imaging (WBMRI; where available) as gold standard. MATERIALS AND MET...
journal_title:Skeletal radiology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00256-008-0607-4
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:To see if there is an association between engagement on physical examination (PE) and the location of the Hill-Sachs lesion (HSL) as assessed by the modified biceps angle. MATERIALS AND METHODS:Sixty-two patients with a history of anterior shoulder dislocation, who underwent preoperative MRI and arthroscopy ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-015-2134-4
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:Image-guided percutaneous bone biopsy may be requested by clinicians to guide antibiotics management decisions in patients with extremity osteomyelitis. Much of the clinical literature describes a high rate of bone biopsy culture positivity in patients with osteomyelitis, but anecdotally biopsy is felt to be ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-019-3152-4
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To demonstrate the anatomy of the extensor retinaculum (ER) of the wrist using gross anatomical correlation with magnetic resonance (MR) imaging before and after ultrasound-guided tenography in four different positions, emphasizing the morphological appearance of the ER that occurs with dorsiflexion of the wr...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-013-1739-8
更新日期:2013-12-01 00:00:00
abstract::Early onset sarcoidosis is a granulomatous disease which is characterized by synovitis, polyarthritis, skin and eye involvement. We report the skeletal features of one patient with a family history and clinical symptoms suggestive of early onset sarcoidosis (EOS) which was confirmed by skin biopsy. Radiographs reveal ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-007-0315-5
更新日期:2007-09-01 00:00:00
abstract::Two patients with osteosarcoma of a lower limb and presumed lymph node metastases are described. The metastases presented in both children as palpable masses, one in the inguinal region and the other in the pelvis. One was visible on plain radiography; both were demonstrated on computed tomography and bone scintigraph...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00361209
更新日期:1989-01-01 00:00:00
abstract::Mesenchymal chondrosarcoma of bone is a rare high-grade variant of chondrosarcoma, which typically has central intramedullary location. The tumor is characterized by admixture of highly anaplastic small round malignant cells and islands of mineralized low-grade hyaline cartilage. It is most unusual for this tumor to a...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-017-2626-5
更新日期:2017-07-01 00:00:00