Abstract：
:We report on three boys suffering from achondroplasia concurrent with enchondromatosis-like metaphyseal changes. Two boys who were examined by molecular analysis harbored a mutation of FGFR3, which occurs in most achondroplastic individuals. Given the prevalence of achondroplasia and enchondromatosis, the metaphyseal changes in these patients are less likely to represent the coincidence of both disorders, but rather to result from a rare consequence of the FGFR3 mutation. Impaired FGFs/FGFR3 signaling pathway in achondroplasia inhibits chondrocytic proliferation, which accounts for most characteristics of achondroplasia. On the other hand, it causes conflicting biological consequences that can suppress or stimulate chondrocytic maturation. In a small subset of achondroplastic individuals, the suppression of chondrocytic maturation may outweigh the stimulation, which leads to cartilaginous overgrowth into the metaphysis, eventually causing the metaphyseal dysplasia found in the present patients.
journal_name
Skeletal Radioljournal_title
Skeletal radiologyauthors
Numakura C,Kobayashi H,Hasegawa Y,Adachi M,Kim OH,Nishimura Gdoi
10.1007/s00256-006-0161-xsubject
Has Abstractpub_date
2007-06-01 00:00:00pages
S29-33eissn
0364-2348issn
1432-2161journal_volume
36 Suppl 1pub_type
杂志文章abstract：:Displaced ulnar collateral ligament injuries of the metacarpophalangeal joint of the thumb, also known as Stener lesions, are a well-recognized clinical entity, requiring surgical intervention because of the trapped location of the torn lateral collateral ligament superficial to the adductor aponeurosis of the thumb. ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-017-2790-7
更新日期：2018-03-01 00:00:00
abstract：:Despite advances in imaging techniques, hip arthrography is still a useful diagnostic tool. We have found that the lateral approach to the hip joint, with the needle inserted superior to the greater trochanter and parallel to the table top under fluoroscopic control, allows easy advancement of the needle into the late...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00243064
更新日期：1992-01-01 00:00:00
abstract：:In a review of 42 cases of degenerative arthritis of the cervical spine and 22 cases of cervical spine trauma with an observed anterior slippage (spondylolisthesis) or posterior slippage (retrolisthesis) of the vertebral bodies of 2 mm or more, characteristic features were observed which allowed distinction between de...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00355101
更新日期：1986-01-01 00:00:00
abstract：:The case of a 58-year-old man with a normal immune status with primary localized skeletal cryptococcosis of the right tibia was presented. Radiologically it appeared as an osteolytic lesion with marginally indistinct borders in the epimetaphyseal region of the proximal tibia. Histologically, necrotizing granulomatous ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00241838
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVE:To determine whether there is an association between T2/T2* mapping and supraspinatus tendon mechanical properties as assessed by shear-wave ultrasound elastography (SWE). MATERIALS AND METHODS:This HIPAA-compliant prospective pilot study received approval from our hospital's institutional review board. Eigh...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-016-2534-0
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVE:To characterize the features and prevalence of radiographic abnormalities of the wrist in children with Kashin-Beck disease (KBD) and to determine whether the presence of radiographic abnormalities in the wrist correlates with the severity of KBD. DESIGN AND PATIENTS:Two hundred and eight posteroanterior rad...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-002-0475-2
更新日期：2002-04-01 00:00:00
abstract：:This study reviews 16 cases of chondroblastoma of the patella which constitute nearly 6% of a large group of chondroblastomas scattered throughout the skeleton. Both radiologic and histologic appearances of chondroblastomas of the patella are indistinguishable from those of chondroblastomas arising in other sites. A r...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00361660
更新日期：1988-01-01 00:00:00
abstract：OBJECTIVE:To compare the histopathology of nodular fasciitis (NF) with the magnetic resonance imaging (MRI) findings in order to evaluate the basis of the MR signal characteristics. DESIGN AND PATIENTS:Ten patients with NF, nine females and 1 male, with an age ranging from 13 to 58 years (mean 26.8 years) were studied...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-001-0462-z
更新日期：2002-03-01 00:00:00
abstract：:For the objective assessment of the severity and progression of osteoporotic deformities of the spine, a mathematical model has been developed which permits evaluation of a single set of radiographs of the spine without reference to absolute values of vertebral height. The model was based on measurements of anterior, ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00197612
更新日期：1990-01-01 00:00:00
abstract：:A painful or rigid subtalar joint is a common clinical problem. Computed tomography (CT) has been shown to be useful in evaluating tarsal coalition, but several other pathologic processes with a similar clinical presentation may affect the subtalar joint. Findings from 45 radiographically abnormal subtalar joints are ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF02569405
更新日期：1989-01-01 00:00:00
abstract：:Magnetic resonance imaging has had a dramatic effect on the means by which we diagnose ligament injuries. Tears resulting from either acute trauma or overuse can be detected noninvasively, directing appropriate therapy be it conservative or surgical. For the elite athlete, earlier diagnosis leads to earlier interventi...
journal_title：Skeletal radiology
pub_type： 杂志文章,评审
doi：10.1007/s002560050476
更新日期：1999-02-01 00:00:00
abstract：:Axial magnetic resonance (MR) imaging of the patellofemoral compartment was performed in 75 patients with arthroscopic correlation. Proton density and T2(2500/20/80) weighted images were obtained in all patients. Chondromalacia in stages I and II could not be reliably identified with MR imaging. For the evaluation of ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00198391
更新日期：1993-01-01 00:00:00
abstract：:Two cases of osteogenic sarcoma with skeletal muscle metastases are described. A 40-year-old woman presented with progressive swelling of both calves and a soft tissue back lump. She had been diagnosed with mandibular chondroblastic osteogenic sarcoma 6 years earlier. Radiographs showed calcified masses. MRI scans and...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s002560050521
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVE:The objective of the present study was to compare the role of single photon emission computed tomography (SPECT), computed tomography (CT) and SPECT-CT of selected volume in lung cancer patients with indeterminate lesions on planar bone scintigraphy (BS). METHODS:The data of 50 lung cancer patients (53 ± 10....
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-011-1304-2
更新日期：2012-07-01 00:00:00
abstract：:The case of a 55-year-old man with chondrosarcoma to the cervical spine is described. Two years previously the patient had undergone a right hip replacement for synovial chondromatosis. Re-evaluation of the biopsy specimen from the right hip taken at the time of the initial operation showed areas of chondrosarcoma ari...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s002560050249
更新日期：1997-06-01 00:00:00
abstract：:A broken needle is a rare complication of bone biopsy. We describe an easily applied technique of retrieval of a retained biopsy needle fragment using a cannulated drill typically used for internal fixation of femoral neck fractures. This approach allows for removal under moderate conscious sedation and can be perform...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-019-03304-y
更新日期：2020-02-01 00:00:00
abstract：:We present a case of sarcoidosis with soft tissue masses and associated phalangeal erosive changes. Sarcoidosis of the musculoskeletal system presenting as a soft tissue mass has been described previously but is rare. To our knowledge, the combination of soft tissue masses and phalangeal erosions has never been descri...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s002560050181
更新日期：1996-11-01 00:00:00
abstract：:We describe two cases of pigmented villonodular synovitis affecting true bursae. This study was also designed to discuss the term "pigmented villonodular bursitis", not confined to true synovial bursae, sometimes creating misunderstanding. ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-002-0491-2
更新日期：2002-06-01 00:00:00
abstract：:The original version of this article unfortunately contained mistake. Fig. 13a (Anatomy of the Ulnar Digital nerve of the Thumb) as originally published erroneously depicts the ulnar digital nerve of the thumb as a branch of the ulnar nerve. ...
journal_title：Skeletal radiology
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00256-018-3037-y
更新日期：2019-01-01 00:00:00
abstract：:Peer-reviewed abstracts presented at the 2008 Society of Skeletal Radiology (SSR) Annual Meeting were reviewed again following oral presentation. Topics representing new concepts, new or novel imaging techniques and instructive case series involving the musculoskeletal system, felt to be of potential interest to inves...
journal_title：Skeletal radiology
pub_type：
doi：10.1007/s00256-008-0531-7
更新日期：2009-01-01 00:00:00
abstract：:Tendinous xanthomata with maximum expression on Achilles tendons are a characteristic feature of cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. Twenty patients are under review; three of them, at different stages of the disease, underwent computed tomographic (CT) examination. CT dem...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00193819
更新日期：1991-01-01 00:00:00
abstract：:We present a rare case of alveolar soft-tissue sarcoma, with extensive bone invasion. The differential diagnosis with bone metastasis and primary bone tumors is discussed. ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s002560050104
更新日期：1996-05-01 00:00:00
abstract：:COVID-19 has presented with a variety of manifestations including peripheral neurological symptoms. The most commonly associated peripheral neuropathies described with COVID-19 are Guillain-Barre syndrome and its variants as well as critical illness polyneuropathy. We report in this paper the distinct MRI findings of ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-021-03721-y
更新日期：2021-01-31 00:00:00
abstract：OBJECTIVE:To demonstrate the anatomy of the extensor retinaculum (ER) of the wrist using gross anatomical correlation with magnetic resonance (MR) imaging before and after ultrasound-guided tenography in four different positions, emphasizing the morphological appearance of the ER that occurs with dorsiflexion of the wr...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-013-1739-8
更新日期：2013-12-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate the efficacy and complications of CT-guided radiofrequency ablation (RFA) of spinal osteoid osteoma (OO). MATERIALS AND METHODS:Between 2002 and 2012, a total of 61 patients (46 male and 15 female, mean age 26.4 ± 12.7 years) were subjected to RFA for spinal OO. The diag...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-017-2662-1
更新日期：2017-08-01 00:00:00
abstract：OBJECTIVE:The transverse relaxation time (T2) in MR imaging has been identified as a potential biomarker of hyaline cartilage pathology. This study investigates whether MR assessments of T2 are comparable between 3-T scanners from three different vendors. DESIGN:Twelve subjects with symptoms of knee osteoarthritis and...
journal_title：Skeletal radiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00256-012-1511-5
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVE:To define the possible mechanism of posture-dependent symptoms of spinal stenosis by measuring the effect of low back posture on morphologic changes of the intervertebral discs and spinal canal in healthy young people. DESIGN:Twenty healthy young volunteers underwent magnetic resonance imaging while supine w...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s002560050596
更新日期：2000-04-01 00:00:00
abstract：:Bisphosphonates have been widely used in the treatment of an array of bone disorders. Recent complications have included unusual femoral fractures in patients who have received long term bisphosphonate treatment for osteoporosis. Although it has been shown that bisphosphonates are effective by blunting osteoclast reso...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-012-1407-4
更新日期：2012-07-01 00:00:00
abstract：:Self-regressing subperiosteal defects appearing during consolidation of fractures were observed in two children aged 6 and 10 years, in the tibia and the radius respectively. These transient defects appeared several weeks after fracture, at a distance from the fracture site. They involved the newly formed subperiostea...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00348864
更新日期：1986-01-01 00:00:00
abstract：:Most authorities favor the hypothesis of an acquired etiology of os odontoideum. We present the cases of identical twin sisters with os odontoideum in association with a congenital partial fusion of the posterior elements of the second and third cervical vertebrae, and discuss the implications. We believe that this is...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00209102
更新日期：1993-10-01 00:00:00
