Abstract:
OBJECTIVE:The objective of the present study was to compare the role of single photon emission computed tomography (SPECT), computed tomography (CT) and SPECT-CT of selected volume in lung cancer patients with indeterminate lesions on planar bone scintigraphy (BS). METHODS:The data of 50 lung cancer patients (53 ± 10.3 years; range 30-75; male/female 38/12) with 65 indeterminate lesions on planar BS (January 2010 to November 2010) were retrospectively evaluated. All of them underwent SPECT-CT of a selected volume. SPECT, CT and SPECT-CT images were independently evaluated by two experienced readers (experience in musculoskeletal imaging, including CT: 5 and 7 years) in separate sessions. A scoring scale of 1 to 5 was used, in which 1 is definitely metastatic, 2 is probably metastatic, 3 is indeterminate, 4 is probably benign and 5 is definitely benign. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for each modality, taking a score ≤2 as metastatic. With receiver operating characteristic (ROC) curve analysis, areas under the curve (AUC) were calculated for each modality and compared. Clinical and imaging follow-up and/or histopathology were taken as reference standard. RESULTS:For both readers SPECT was inferior to CT (P = 0.004, P = 0.022) and SPECT-CT (P = 0.003, P = 0.037). However, no significant difference was found between CT and SPECT-CT for reader 1 (P = 0.847) and reader 2 (P = 0.592). The findings were similar for lytic as well as sclerotic lesions. Moderate inter-observer agreement was seen for SPECT images (к = 0.426), while almost perfect agreement was seen for CT (к = 0.834) and SPECT-CT (к = 0.971). CONCLUSION:CT alone and SPECT-CT are better than SPECT for accurate characterisation of indeterminate lesions on planar BS in lung cancer patients. CT alone is not inferior to SPECT-CT for this purpose and might be preferred because of shorter acquisition time and wider availability.
journal_name
Skeletal Radioljournal_title
Skeletal radiologyauthors
Sharma P,Kumar R,Singh H,Bal C,Julka PK,Thulkar S,Malhotra Adoi
10.1007/s00256-011-1304-2subject
Has Abstractpub_date
2012-07-01 00:00:00pages
843-50issue
7eissn
0364-2348issn
1432-2161journal_volume
41pub_type
杂志文章abstract::Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) represents a rare subclassification of peripheral T-cell lymphoma (PTCL). We present a case of a 21-year-old female who presented with a 1-month history of pain in the left buttock and hip, tender left inguinal lymph nodes, fevers, and night sweats. Percutaneous c...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-014-1879-5
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:To evaluate the morphology and location of vertebral endplate changes, and to analyze their association with age, gender, and body mass index (BMI). DESIGN AND PATIENTS:At 1.5 T (T1-weighted, T2-weighted/STIR) 100 lumbar spines were evaluated separately by three observers. The readers classified the endplate b...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-004-0886-3
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the efficacy and complications of CT-guided radiofrequency ablation (RFA) of spinal osteoid osteoma (OO). MATERIALS AND METHODS:Between 2002 and 2012, a total of 61 patients (46 male and 15 female, mean age 26.4 ± 12.7 years) were subjected to RFA for spinal OO. The diag...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-017-2662-1
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:To assess clinical and MRI features of Langerhans cell histiocytosis in the pelvis and extremities. MATERIALS AND METHODS:The MRI and clinical features of 21 pathologically proven cases of LCH involving the pelvis and extremities were studied. Multiple characteristics of the lesions were evaluated (location,...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-016-2330-x
更新日期:2016-05-01 00:00:00
abstract::Primary perivascular epithelioid cell neoplasms (PEComas) of bone are rare mesenchymal tumors. Histologically, they are composed predominantly of perivascular epithelioid cells and have the capacity to metastasize. PEComas have been reported within intra-abdominal and intra-pelvic organs. To the best of our knowledge,...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-012-1479-1
更新日期:2012-11-01 00:00:00
abstract::The purpose of this article is to review calcified or ossified benign soft tissue lesions that may simulate malignancy. We review the clinical presentations, locations, imaging characteristics, and differential diagnostic considerations of myositis ossificans, tophaceous gout, benign vascular lesions, calcific tendino...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-019-03272-3
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:The objective was to study the natural course of Modic type 1 change (M1) in relation to lumbar disc degeneration. MATERIALS AND METHODS:Twenty-four chronic low back pain (LBP) patients with M1 on lumbar spine were selected from 1,015 patients with magnetic resonance imaging from a follow-up study lasting fo...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-008-0611-8
更新日期:2009-03-01 00:00:00
abstract::Melanotic neuroectodermal tumor of infancy (MNTI) is an uncommon tumor of neural crest origin, almost invariably identified in the head and neck region. It is a relatively benign tumor but can recur and rarely metastasize. Herein, a rare case of MNTI in the thigh of an infant is documented. Radiographic imaging showed...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-011-1113-7
更新日期:2011-08-01 00:00:00
abstract::Thirty one patients suffering from myelopathy associated with ossification of the posterior longitudinal ligament and ligamentum flavum of the spine have been investigated. The pattern of spinal and peripheral hyperostosis was recorded in each case. Flowing anterior vertebral hyperostosis and ligamentous ossification ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00360789
更新日期:1983-01-01 00:00:00
abstract::Posterior or lateral dislocation of the long head of biceps is a rare complication of shoulder dislocation that can result in inability to relocate the humerus. The diagnosis should be suspected when certain radiographic features are present at the initial presentation. Other imaging modalities can aid diagnosis when ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-007-0285-7
更新日期:2007-08-01 00:00:00
abstract::A patient with chronic renal failure and progressive symmetrical ilial pseudofractures (Looser zones, Milkman's syndrome) is presented. The literature is reviewed in light of the findings in this patient, and possible mechanisms of pseudofracture formation are discussed. ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF02219626
更新日期:1982-01-01 00:00:00
abstract::Giant cell tumor (GCT) is a rare complication of Paget disease of bone. It usually occurs in the skull or pelvic bones of patients with long-standing polyostotic disease. This report describes a 62-year-old patient who presented with monostotic Paget disease of the distal femur complicated by GCT. He had a 2-year hist...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-007-0310-x
更新日期:2007-10-01 00:00:00
abstract::We present a rare case of alveolar soft-tissue sarcoma, with extensive bone invasion. The differential diagnosis with bone metastasis and primary bone tumors is discussed. ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050104
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVE:Burnout is a job-related psychological syndrome with three aspects: emotional exhaustion, depersonalization, and perceived lack of personal accomplishment. Burnout is associated with deleterious effects on both workers and their work. When burnout affects physicians, their well-being, longevity, and care of p...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-017-2578-9
更新日期:2017-04-01 00:00:00
abstract::The radiomorphological appearance of fibrous metaphyseal defects (FMDs) is demonstrated by long-term follow-up studies. A characteristic radiomorphological course rather than a typical single appearance can be established. These findings correlate well with the duration of these tumor-like lesions; therefore, the radi...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00361448
更新日期:1988-01-01 00:00:00
abstract::Self-regressing subperiosteal defects appearing during consolidation of fractures were observed in two children aged 6 and 10 years, in the tibia and the radius respectively. These transient defects appeared several weeks after fracture, at a distance from the fracture site. They involved the newly formed subperiostea...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00348864
更新日期:1986-01-01 00:00:00
abstract::Digital and manual subtraction images obtained during the arthrographic evaluation of 78 painful hip prostheses were reviewed retrospectively. Revision arthroplasty was performed in 53 of these cases, and the arthrographic and surgical findings were correlated. The digital and manual subtraction images were evaluated ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00191080
更新日期:1991-01-01 00:00:00
abstract::In a collection of 101 anatomical preparations of the human pelvis, ossification of the sacrotuberous ligament was found in 8 cases. In 7 of these, the ossification showed a characteristic intraligamentous morphology, with a broad-based origin at the ischial tuberosity and tapering off craniomedially. The length varie...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00197139
更新日期:1993-11-01 00:00:00
abstract::A recent publication showed the earliest signs of renal osteodystrophy in patients on maintenance hemodialysis (MHD) to occur in the tufts [1]. We present three patients on MHD, in two of whom the earliest unequivocal radiographic improvement was seen in the tufts. The third patient had been on MHD and, following subt...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00580598
更新日期:1980-01-01 00:00:00
abstract::Bisphosphonates have been widely used in the treatment of an array of bone disorders. Recent complications have included unusual femoral fractures in patients who have received long term bisphosphonate treatment for osteoporosis. Although it has been shown that bisphosphonates are effective by blunting osteoclast reso...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-012-1407-4
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:To evaluate high-resolution MRI of the proximal zone of the lunotriquetral ligament (LTL) using a microscopy surface coil with a 1.5 T scanner. DESIGN AND SUBJECTS:The proximal zone of the LTL was reviewed in 90 subjects (23 asymptomatic normal volunteers and 67 patients with suspicion of triangular fibrocar...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-005-0070-4
更新日期:2006-05-01 00:00:00
abstract::Soft tissue sarcomas (STS) are rare. Affected patients are at increased risk of developing a second primary malignancy, particularly another primary STS. These rarely affect the extremities, tending to occur in the abdomen, head or neck. We describe a patient with myxofibrosarcoma of the buttock who developed a second...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-011-1123-5
更新日期:2011-08-01 00:00:00
abstract::The total bone width (T) and medullary width (M) of the humerus and femur of 216 and 138 Nigerian newborn infants, respectively, were measured in order to determine the normal standards for cortical bone mass in the newborn. The cortical width (C), cortical area (CA), and percentage cortical area (PCA) were calculated...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00349862
更新日期:1986-01-01 00:00:00
abstract::In summary, a case is reported of a patient with the radiographic findings of diffuse, symmetrical metaphyseal osteopenia of long bones. A constellation termed neo-osseous porosis, associated with polyendocrine failure (Schmidt syndrome) involving the thyroid gland, adrenal glands, and gonads has been described in thi...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00241809
更新日期:1990-01-01 00:00:00
abstract::Osteosarcoma is the commonest primary malignant bone tumour in children and adolescents, the majority of cases being conventional intra-medullary high-grade tumours affecting the appendicular skeleton. Treatment is typically with a combination of neo-adjuvant chemotherapy, tumour resection with limb reconstruction and...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-018-3079-1
更新日期:2019-04-01 00:00:00
abstract::Three cases of calcific tendinitis occurring at an unusual site (vastus lateralis tendon) are described. Findings on conventional radiography and computed tomography together with the clinical history are characteristic for this disorder and reflect its natural evolution. The actual role of magnetic resonance imaging ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00243716
更新日期:1991-01-01 00:00:00
abstract::Juxta-articular inflammatory masses, sternomanubrial or sternoclavicular, were noted in two women who were subsequently found to have ankylosing spondylitis. The differential diagnosis of juxta-articular masses should include systemic rheumatic disorders as well as tumor or infection. ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00367763
更新日期:1987-01-01 00:00:00
abstract::While well-recognized in the orthopedic literature as a cause of chronic hip pain, acetabular retroversion has not been specifically described in the radiologic literature. Acetabular retroversion represents a particular form of hip dysplasia characterized by abnormal posterolateral orientation of the acetabulum. This...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-006-0150-0
更新日期:2007-06-01 00:00:00
abstract::Inflammatory myopathies encompass a group of acquired muscle disorders caused by infectious agents (bacteria, viruses, fungi and parasitic agents) or autoimmune processes (polymyositis, dermatomyositis and other types). In suspected infection sonography, CT and MRI are all able to show edema and fluid collections in s...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s002560000238
更新日期:2000-08-01 00:00:00
abstract::Anterior cruciate ligament (ACL) reconstructions have increased over the past 25 years. The increased incidence of ACL reconstructions has translated into a larger number of graft failures and revision ACL procedures. It is important to understand the causes of graft failure when evaluating for a revision ACL reconstr...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-016-2535-z
更新日期:2017-02-01 00:00:00