Giant cell tumor complicating Paget disease of long bone.

Abstract:

:Giant cell tumor (GCT) is a rare complication of Paget disease of bone. It usually occurs in the skull or pelvic bones of patients with long-standing polyostotic disease. This report describes a 62-year-old patient who presented with monostotic Paget disease of the distal femur complicated by GCT. He had a 2-year history of discomfort and pain in his left knee. Conventional plain films and MRI demonstrated the characteristic bone changes of Paget disease and an associated lytic lesion involving the epiphyseal and metaphyseal regions of the distal femur. A diagnostic curettage showed the characteristic histopathologic features of Paget disease and GCT. There was no evidence of malignancy. The clinicopathologic features of this rare lesion are described and correlated with a review of the literature.

journal_name

Skeletal Radiol

journal_title

Skeletal radiology

authors

Hoch B,Hermann G,Klein MJ,Abdelwahab IF,Springfield D

doi

10.1007/s00256-007-0310-x

subject

Has Abstract

pub_date

2007-10-01 00:00:00

pages

973-8

issue

10

eissn

0364-2348

issn

1432-2161

journal_volume

36

pub_type

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