Abstract:
PURPOSE:To determine the value of prebiopsy 18F-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET)/computed tomography (CT) in discriminating malignant from benign vertebral bone lesions. MATERIALS AND METHODS:This retrospective study included 53 patients with 55 vertebral bone lesions that underwent FDG-PET/CT before CT-guided biopsy. Pathologic examination of the biopsy sample and a minimum follow-up of 1 year were used as reference standard. RESULTS:Sensitivity, specificity, positive predictive value, and negative predictive value of visual FDG-PET analysis (with lesion FDG uptake higher than liver FDG uptake as threshold for malignancy) in discriminating malignant from benign vertebral bone lesions were 91.3% (42/46), 22.2% (2/9), 85.7% (42/49), and 33.3% (2/6), respectively. The semiquantitative FDG-PET metrics SUVmax and SUVpeak achieved areas under the receiver operating characteristics curve of 0.630 and 0.671, respectively. Malignant lesions demonstrated bone lysis more frequently than benign lesions (60.9% (28/46) vs. 22.2% (2/9)), and this difference was nearly significant (P = 0.064). All other clinical and conventional imaging characteristics (including patient age, gender, previous diagnosis of malignancy, bone pain, weight loss, any CT abnormality, sclerosis, cortical destruction, bone marrow replacement, associated extraosseous soft tissue mass, and accompanying vertebral height loss, multiple bone lesions on FDG-PET/CT, and suspicious extraosseous lesions on FDG-PET/CT) were not significantly different (P = 0.143 to 1.000). CONCLUSION:FDG-PET/CT may steer the diagnosis (particularly thanks to a relatively high PPV and value of semiquantitative measurements), but cannot always classify vertebral bone lesions as malignant or benign with sufficient certainty. In these cases, biopsy and/or follow-up remain necessary to establish a final diagnosis.
journal_name
Skeletal Radioljournal_title
Skeletal radiologyauthors
Loudini N,Glaudemans AWJM,Jutte PC,Yakar D,Kwee TCdoi
10.1007/s00256-020-03426-8subject
Has Abstractpub_date
2020-09-01 00:00:00pages
1387-1395issue
9eissn
0364-2348issn
1432-2161pii
10.1007/s00256-020-03426-8journal_volume
49pub_type
杂志文章abstract::We report two sisters who have a rare skeletal abnormality termed Patterson-Lowry rhizomelic dysplasia. The typical findings of these cases on bone survey are isolated shortening and proximal metaphyseal enlargement and cupping of the bilateral humeri. The elder sister also has coxa vara deformity and dysplastic proxi...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-014-1957-8
更新日期:2014-11-01 00:00:00
abstract::MRI of a 62-year-old female presenting with ankle pain demonstrated an accessory muscle within the anterior compartment of the lower leg. The muscle originated from the fibula and anterior crural septum. The tendon passed anterior to the lateral malleolus and inserted at the critical angle of Gissane on the calcaneus....
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-014-2021-4
更新日期:2015-05-01 00:00:00
abstract::Behcet's disease is a chronic inflammatory condition involving several organs, such as the skin, mucous membranes, eyes, joints, intestines, lungs and central nervous system. It rarely affects the spinal column. We describe a case of progressive atlanto-axial subluxation in a 44-year-old woman with Behcet's disease. T...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-009-0815-6
更新日期:2010-03-01 00:00:00
abstract::A case of Petriellidium boydii (synonym: Allescheria boydii) infection of the knee joint is described. It followed a penetrating soft tissue injury with a pitchfork. Such infections are rare in this country and bone involvement has not been recorded previously except in maduramycosis contracted in tropical areas. ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00360494
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:This study observed the distribution of CT attenuation values for T10-L3 vertebral bodies and derived the Hounsfield unit (HU) thresholds using the quantitative computed tomography (QCT) as a reference to predict osteoporosis and normal bone density. METHODS:We included 482 subjects who were scheduled to und...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-020-03573-y
更新日期:2021-02-01 00:00:00
abstract::In computed tomography of the skeleton, as in other radiologic modalities, recognition of normal skeletal variants is essential for defining the extent and type of injury or neoplasm. Computed tomography findings, because of the unique use of cross-sectional anatomy, must be carefully studied to avoid labeling a norma...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00357773
更新日期:1983-01-01 00:00:00
abstract::A 23-year-old woman with a medical history significant for tuberous sclerosis presented with symptoms of postpartum endometritis. Focal gigantism of the third digit of her right hand was incidentally noted and is reported to be a rare manifestation of tuberous sclerosis. ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050486
更新日期:1999-02-01 00:00:00
abstract:OBJECTIVE:Bone strength depends on both mineral content and bone structure. The aim of this in vitro study was to develop a method of quantitatively assessing trabecular bone structure by applying three-dimensional image processing to data acquired with multi-slice and cone-beam computed tomography using micro-computed...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-013-1766-5
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:To determine the ability of 3.0T magnetic resonance (MR) imaging to identify partial tears of the anterior cruciate ligament (ACL) and to allow distinction of complete from partial ACL tears. MATERIALS AND METHODS:One hundred seventy-two patients were prospectively studied by 3.0T MR imaging and arthroscopy in...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-010-1044-8
更新日期:2011-06-01 00:00:00
abstract::Fibroma of the tendon sheath, a rare benign soft tissue tumor that most often occurs in the distal upper extremities (hands and wrist), is exceedingly rare to present as an intraarticular mass. Presented here is the first case in the English literature, to our knowledge, of a fibroma of the tendon sheath arising in th...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-013-1749-6
更新日期:2014-05-01 00:00:00
abstract:PURPOSE:To evaluate the morphology and location of vertebral endplate changes, and to analyze their association with age, gender, and body mass index (BMI). DESIGN AND PATIENTS:At 1.5 T (T1-weighted, T2-weighted/STIR) 100 lumbar spines were evaluated separately by three observers. The readers classified the endplate b...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-004-0886-3
更新日期:2005-03-01 00:00:00
abstract::Four patients with histologically confirmed osteonecrosis of the first metatarsal sesamoid are presented. No patient was an athlete, nor recalled any noticeable trauma or significant stress as having occurred to the feet. No foot deformities or joint malalignments were found. Excellent results were obtained by excisio...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00350208
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:To characterize the appearance, location, severity, and prevalence of focal glenoid retroversion on shoulder MRI in professional baseball pitchers versus age-matched controls. MATERIALS AND METHODS:In this retrospective review, two musculoskeletal radiologists evaluated shoulder MRI examinations from 40 prof...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-018-3121-3
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:The purpose of the study was to determine if the thickness of the subacromial-subdeltoid (SASD) bursa during dynamic ultrasound and on static views differs between patients with shoulder impingement syndrome and healthy volunteers. MATERIALS AND METHODS:Twenty-two patients with a clinical diagnosis of should...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-011-1295-z
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:To describe the CT and MR imaging appearance of both osseous and extraosseous manifestations of melorheostosis. DESIGN AND PATIENTS:We retrospectively reviewed the CT (n=7) and/or MR imaging findings (n=12) of 17 patients with characteristic radiographic findings of melorheostosis (undulating cortical hypero...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560100366
更新日期:2001-08-01 00:00:00
abstract::We report an 89-year-old woman with bilateral atraumatic scapular spine fracture several months after bilateral reverse total shoulder arthroplasty (RTSA). Recently, RTSA has gained popularity in the surgical treatment of complex shoulder disorders such as cuff tear arthropathy. However, scapular fractures may occur s...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-013-1775-4
更新日期:2014-05-01 00:00:00
abstract::The ischiorectal fossa may give rise to a wide variety of pathological entities, although it is composed of relatively few structures. Developmental cysts are included among the list. Large epidermoid cysts in the ischiorectal fossa have been previously described (Fujimoto et al., Clin Imaging 17:146-148, 1993; Ng et ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-009-0705-y
更新日期:2009-09-01 00:00:00
abstract::Forces and torques, due to a 0.3 Tesla magnetic field were evaluated on ten hip prostheses and ten hemostat clips. Measurements were performed with an instrument utilizing the movement of a laser beam caused by the deflection of a cantilever. The results indicate effects, if any, to be smaller than the instrument's se...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00355565
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:Bony ankylosis has been described following trauma, paralysis, psoriasis, Reiter's syndrome, ankylosing spondylitis, juvenile chronic arthritis and rheumatoid arthritis. Reports of bony ankylosis following thermal and electrical injury are limited. DESIGN AND PATIENTS:Thirteen cases of burn-related joint ank...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560100342
更新日期:2001-07-01 00:00:00
abstract::A case of focal resorption in a limb salvage/bone allograft is presented, illustrating that roentgenological differentiation from other causes for graft resorption may be very difficult. The possibilities of infection and tumor recurrence, as well as "physiologic" graft resorption, must be considered in the differenti...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00563211
更新日期:1994-02-01 00:00:00
abstract::Osseous metastases to the hand and wrist are uncommon. Most cases represent the manifestation of known malignancy with disseminated disease. Less commonly, acrometastases are the initial presentation of malignancy. In both instances, diagnosis of malignancy is frequently not considered either clinically or radiographi...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00198077
更新日期:1995-02-01 00:00:00
abstract::This is a brief review of the physical and physiologic aspects and theories of thermography and its clinical use in musculoskeletal conditions. Thermography is a simple, non-invasive procedure with a potential for usefulness. However, the majority of clinical studies to date have not been performed independent of othe...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00361052
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:To assess the degree of fluid-fluid levels on MRI in spinal tumours compared with final diagnosis, and the outcome of needle biopsy in such cases. MATERIALS AND METHODS:Retrospective review of patients with a spinal tumour that contained fluid-fluid levels. Data collected included age, sex, spinal location, ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-020-03621-7
更新日期:2020-09-25 00:00:00
abstract:OBJECTIVE:To delineate the spectrum of knee injuries associated with sprains and tears of the distal iliotibial band (ITB). MATERIALS AND METHODS:A retrospective review of 200 random MRI scans undertaken for acute knee trauma was performed. Scans were excluded if there was a history of injury over 4 weeks from the tim...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-014-1918-2
更新日期:2014-10-01 00:00:00
abstract:PURPOSE:To re-evaluate the relationship between os acromiale and rotator cuff tears. METHODS:We retrospectively analyzed 84 magnetic resonance imaging studies of the shoulder. Forty-two subjects with os acromiale (n = 42; 32 men and ten women, age 25-81 years, mean 47.6 years) were compared with age- and gender-matche...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-007-0305-7
更新日期:2007-09-01 00:00:00
abstract::Spindle cell hemangioendothelioma occurring in skeletal muscle is extremely rare. No reported studies have performed an imaging evaluation of intramuscular spindle cell hemangioendothelioma. We report on such a tumor arising in an unusual site, the right extensor digiti minimi, in a 46-year-old woman. An en bloc resec...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050551
更新日期:1999-08-01 00:00:00
abstract:PURPOSE:The quantitative assessment of muscle atrophy has a degree of importance in prognosticating rotator cuff treatment. However, it has been conjectured that muscle fat increases with aging. Therefore, we thought that the quantitative assessment of the supraspinatous would be better if made in comparison with a sta...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-007-0307-5
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:Post-operative shoulder patients are often difficult to image due to scar tissue, metallic artifact, and residual irregularity of anatomic structures. The purpose of this study was to assess MR versus MR arthrography versus CT arthrography in the post-operative shoulder. Also, we assessed whether injecting CT...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-018-2927-3
更新日期:2018-09-01 00:00:00
abstract::Tunnel cyst formation is a rare complication after anterior cruciate ligament reconstruction, usually occurring 1-5 years post-operatively, which may occasionally be symptomatic. There are multiple proposed theories regarding the etiology of tunnel cysts. Theories include necrosis, foreign-body reaction, lack of compl...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-012-1486-2
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:The purpose of the study was to evaluate the appearance of "cubital bursitis" on ultrasonography and CT and MR imaging. "Cubital bursitis" is a rare pathological condition involving a large swelling of the bicipito-radial or interosseous bursae located at the insertion of the distal biceps tendon on the radia...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050117
更新日期:1996-07-01 00:00:00