Abstract：
:Bisphosphonates have been widely used in the treatment of an array of bone disorders. Recent complications have included unusual femoral fractures in patients who have received long term bisphosphonate treatment for osteoporosis. Although it has been shown that bisphosphonates are effective by blunting osteoclast resorption, there has been little morphologic description of the local tissue activity at the site of these unusual fractures. To evaluate for local changes to bone morphology at the fracture site in patients presenting with a bisphosphonate-related femur fracture, a sample of cortical bone was obtained at the site of a bisphosphonate fracture and was processed in a nondecalcified manner. The specimen was evaluated for potential cellular changes consistent with bisphosphonate treatment. Significant osteoclast abnormalities at the fracture site were found in a 69-year-old woman treated for 2 years with Fosamax substantiating that bone remodeling at this site is distinctly abnormal. Addressing the osteoclast dysfunction should be a focus of future therapeutic attention and intervention.
journal_name
Skeletal Radioljournal_title
Skeletal radiologyauthors
Vigorita VJ,Silver JS,Eisemon EOdoi
10.1007/s00256-012-1407-4subject
Has Abstractpub_date
2012-07-01 00:00:00pages
861-5issue
7eissn
0364-2348issn
1432-2161journal_volume
41pub_type
杂志文章abstract：:Fractures of the anterior process of the calcaneus are often missed. This error follows from the tendency to focus exclusively on the mortise and malleoli when a history of ankle trauma is supplied. Seven patients with this fracture are presented. The anatomy, mechanism of injury, clinical presentation, and the radiog...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00349747
更新日期：1985-01-01 00:00:00
abstract：OBJECTIVE:Determine the prevalence of the accessory sacroiliac joint in the pediatric population and describe variant sacroiliac joint morphology that may predispose patients to the development of an accessory sacroiliac joint. MATERIALS AND METHODS:One hundred and seventy-eight high-resolution pelvic CT scans of pati...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-020-03608-4
更新日期：2021-03-01 00:00:00
abstract：:Liposarcoma is a relatively common soft tissue malignancy with a wide spectrum of clinical presentations and imaging appearances. Several subtypes are described, ranging from lesions nearly entirely composed of mature adipose tissue, to tumors with very sparse adipose elements. The imaging appearance of these fatty ma...
journal_title：Skeletal radiology
pub_type： 杂志文章,评审
doi：10.1007/s00256-003-0647-8
更新日期：2003-09-01 00:00:00
abstract：:Cortical desmoids are self-limiting fibro-osseous lesions commonly occurring at the medial supracondylar femur in active adolescents, at either the origin of the medial head of the gastrocnemius or at the insertion of the adductor magnus aponeurosis. Less commonly, in a similar demographic, cortical desmoids may occur...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-017-2638-1
更新日期：2017-07-01 00:00:00
abstract：:The ball-and-socket ankle joint is a malformation of the ankle in which the articular surface of the talus is hemispherical in both the anteroposterior and lateral projections and has a congruent, concave tibial articular surface. Fourteen patients with this condition were identified retrospectively. Thirteen patients...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00350538
更新日期：1987-01-01 00:00:00
abstract：OBJECTIVE:To establish a high-resolution US technique that enables a systematic morphometric examination of the three components that form the distal biceps brachii tendinous complex; the internal bicipital aponeurosis, the distal biceps brachii tendon and the external bicipital aponeurosis (also known as lacertus fibr...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-018-3043-0
更新日期：2019-03-01 00:00:00
abstract：:Subchondral signal abnormalities are often present on magnetic resonance (MR) images of patients with osteoarthritis, but no study correlating these changes with histopathology has been published. We selected nine consecutive patients with clinical and radiographic diagnosis of moderate to severe osteoarthritis of the...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00204605
更新日期：1994-08-01 00:00:00
abstract：:Lysinuric protein intolerance (LPI) is an autosomal recessive disease caused by defective transport of the cationic amino acids lysine, arginine, and ornithine at the cell membrane. About 80 patients with LPI have been described worldwide, almost half of them in Finland. The symptoms appear in early childhood as a fai...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00191519
更新日期：1993-01-01 00:00:00
abstract：:The magnetic resonance imaging characteristics of two surgically proven cases of pigmented villonodular synovitis are reported. On the short TR/TE pulse sequences, the synovium has an intermediate signal intensity. Long TR/TE pulse sequences show the synovium containing areas of increased signal interspersed with decr...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00361475
更新日期：1987-01-01 00:00:00
abstract：:The weight of the head and trunk is transferred to the lower extremities through that segment of the spine articulating either directly or indirectly with the ilii. When a lumbosacral transitional vertebra is present the position of the weight-bearing platform usually changes. A bony entity is formed delineated superi...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00349578
更新日期：1982-01-01 00:00:00
abstract：OBJECTIVE:To examine the association between inframalleolar peroneal tendon abnormalities and an enlarged peroneal tubercle. MATERIALS AND METHODS:Two independent readers evaluated consecutive ankle MR imaging studies to classify inframalleolar peroneal tendon findings as normal, tenosynovitis, partial tear or complet...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-013-1725-1
更新日期：2013-12-01 00:00:00
abstract：PURPOSE:To identify correlated signs on non-enhanced MRI that might improve diagnostic detection of plantar plate (PP) tear. MATERIALS AND METHODS:We performed an IRB-approved, HIPAA-compliant retrospective analysis of 100 non-contrast MRI (50 PP tear, 50 controls). All were anonymized, randomized, and reviewed; 20 we...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-016-2375-x
更新日期：2016-07-01 00:00:00
abstract：:In a review of 42 cases of degenerative arthritis of the cervical spine and 22 cases of cervical spine trauma with an observed anterior slippage (spondylolisthesis) or posterior slippage (retrolisthesis) of the vertebral bodies of 2 mm or more, characteristic features were observed which allowed distinction between de...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/BF00355101
更新日期：1986-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to exploit the normal nature of peroneal nerve anatomy to identify constant magnetic resonance imaging (MRI) patterns in peroneal intraneural ganglia. DESIGN:This study is designed as a retrospective clinical study. MATERIALS AND METHODS:MR images of 25 patients with peroneal intran...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-008-0545-1
更新日期：2008-12-01 00:00:00
abstract：OBJECTIVE:The purpose of this article was to evaluate the radiologic findings of adult pelvis and appendicular skeletal Langerhans cell histiocytosis (LCH), emphasizing the CT and MR findings. MATERIALS AND METHODS:The images of nine patients with pathologically proven LCH (five men and four women; mean age, 37.11 yea...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-010-1078-y
更新日期：2011-11-01 00:00:00
abstract：:Plantar fat pad syndrome has received little attention in the literature. A variety of structural changes of the plantar fat pad have been described in the literature, including atrophy, contusion, and fractured fat pad. This case series presents 4 patients (5 heels) with subluxation of a fractured plantar fat pad on ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-020-03639-x
更新日期：2020-11-02 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate the efficacy and complications of CT-guided radiofrequency ablation (RFA) of spinal osteoid osteoma (OO). MATERIALS AND METHODS:Between 2002 and 2012, a total of 61 patients (46 male and 15 female, mean age 26.4 ± 12.7 years) were subjected to RFA for spinal OO. The diag...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-017-2662-1
更新日期：2017-08-01 00:00:00
abstract：:Osteosarcomas arising in irradiated tissues are uncommon but important complications of radiotherapy. Radiation-induced osteosarcomas generally occur 3-30 years after exposure and are most common after radiotherapy for cervical or breast carcinoma. These tumors are usually rapidly growing, extremely painful, and histo...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s002560050144
更新日期：1996-08-01 00:00:00
abstract：:Hibernoma is a benign adipose tumour that contains foetal brown fat cells. We report a case of hibernoma arising in the left ischium of a 65-year-old female with a past history of ovarian carcinoma. The patient presented with a relatively short history of left sacral/hip pain. Radiologically, the lesion, which was lar...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-016-2460-1
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVE:We investigated the usefulness of plain film and MR findings in predicting the outcome of conservatively treated patients with femoral osteochondritis dissecans. DESIGN:Without knowledge of the clinical outcome, we retrospectively reviewed the initial plain films and MR examinations. Each MR examination was ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s002560050267
更新日期：1997-08-01 00:00:00
abstract：OBJECTIVE:This study aims to quantitatively characterize the distribution of subchondral bone density across the human femoral head using a computed tomography derived measurement of bone density and a common reference coordinate system. MATERIALS AND METHODS:Femoral head surfaces were created bilaterally for 30 patie...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-011-1270-8
更新日期：2012-06-01 00:00:00
abstract：:Primary neoplastic vascular lesions of bone are rare, and include haemangiomas, haemangioendothelioma, epithelioid haemangioendothelioma and angiosarcoma. These lesions may be multicentric, and when they involve bone are typically intraosseous and lytic. Radiological findings are not always specific. We report a case ...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-005-0060-6
更新日期：2006-10-01 00:00:00
abstract：PURPOSE:To determine the value of prebiopsy 18F-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET)/computed tomography (CT) in discriminating malignant from benign vertebral bone lesions. MATERIALS AND METHODS:This retrospective study included 53 patients with 55 vertebral bone lesions that underwent FDG-...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-020-03426-8
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:To describe the normal motion pattern at the midcarpal compartment during active radial-ulnar deviation of the wrist using dynamic MRI, and to determine the observer performance for measurements obtained in asymptomatic volunteers. METHODS:Dynamic MRI of 35 wrists in 19 asymptomatic volunteers (age mean 30.4...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-019-03266-1
更新日期：2020-02-01 00:00:00
abstract：OBJECTIVE:To report 12 cases of chondrosarcoma in a rare location, the short tubular bones of the hands and feet, as well as 12 cases of enchondroma in similar locations, emphasizing the radiologic and histopathologic features. DESIGN AND PATIENTS:All relevant cases that had both histologic slides and radiographs avai...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s002560050448
更新日期：1998-11-01 00:00:00
abstract：OBJECTIVE:To investigate the MR findings of necrotic lesions and the extralesional area of osteonecrosis of the femoral head (ONFH) for each of the radiological stages. DESIGN AND PATIENTS:Forty-nine hips in 29 patients (15 female, 14 male; mean age 38 years, range 17-59 years) were imaged using a 1.0-T superconductin...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s002560050583
更新日期：2000-03-01 00:00:00
abstract：OBJECTIVE:To describe the imaging features of plexiform fibrohistiocytic tumor and its associated clinical findings. MATERIALS AND METHODS:An institutional database was searched to identify all patients with a pathological diagnosis of plexiform fibrohistiocytic tumor. The electronic medical record was reviewed for re...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-018-3050-1
更新日期：2019-03-01 00:00:00
abstract：OBJECTIVE:Post-operative shoulder patients are often difficult to image due to scar tissue, metallic artifact, and residual irregularity of anatomic structures. The purpose of this study was to assess MR versus MR arthrography versus CT arthrography in the post-operative shoulder. Also, we assessed whether injecting CT...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-018-2927-3
更新日期：2018-09-01 00:00:00
abstract：:Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) represents a rare subclassification of peripheral T-cell lymphoma (PTCL). We present a case of a 21-year-old female who presented with a 1-month history of pain in the left buttock and hip, tender left inguinal lymph nodes, fevers, and night sweats. Percutaneous c...
journal_title：Skeletal radiology
pub_type： 杂志文章,评审
doi：10.1007/s00256-014-1879-5
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVE:To compare the histopathology of nodular fasciitis (NF) with the magnetic resonance imaging (MRI) findings in order to evaluate the basis of the MR signal characteristics. DESIGN AND PATIENTS:Ten patients with NF, nine females and 1 male, with an age ranging from 13 to 58 years (mean 26.8 years) were studied...
journal_title：Skeletal radiology
pub_type： 杂志文章
doi：10.1007/s00256-001-0462-z
更新日期：2002-03-01 00:00:00
