Familial early onset sarcoidosis with bone cysts and erosions.

Abstract:

:Early onset sarcoidosis is a granulomatous disease which is characterized by synovitis, polyarthritis, skin and eye involvement. We report the skeletal features of one patient with a family history and clinical symptoms suggestive of early onset sarcoidosis (EOS) which was confirmed by skin biopsy. Radiographs reveal postarthritic deformities of the MCP joints, contractures, a coarsened trabecular pattern at the PIP joints and small bone cysts resembling osteitis cystoides multiplex. Similar lesions were described in radiographs of the older sister and an uncle of our patient. This is the first report demonstrating bone cysts and erosions which could be a diagnostic feature in this rare disease and may help to differentiate other rheumatoid disorders.

journal_name

Skeletal Radiol

journal_title

Skeletal radiology

authors

Blank N,Max R,Autschbach F,Libicher M,Lorenz HM

doi

10.1007/s00256-007-0315-5

subject

Has Abstract

pub_date

2007-09-01 00:00:00

pages

891-3

issue

9

eissn

0364-2348

issn

1432-2161

journal_volume

36

pub_type

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