The "lamellated" skull in beta-thalassaemia.

Abstract:

:The skull in homozygous beta-thalassaemia may present several abnormalities, such as osteopenia, widening of the diploic space, and a "hair-on-end" appearance. In some cases it presents also a particular stratified appearance caused by a variable number of osseous lamellae, parallel with the inner table. This "lamellated skull" was observed in 16 out of 150 patients affected by the disease (10.6%). Possible mechanisms are discussed. The lamellar osseous changes could be due to repeated periosteal osteoblastic reactions to the sinusoidal neovascularization associated with marrow hyperplasia in poorly transfused patients.

journal_name

Skeletal Radiol

journal_title

Skeletal radiology

authors

Orzincolo C,Castaldi G,Scutellari PN,Franceschini F

doi

10.1007/BF00361428

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

373-6

issue

5

eissn

0364-2348

issn

1432-2161

journal_volume

18

pub_type

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