当前位置： SCI文献检索 > MOLECULAR AND CELLULAR ENDOCRINOLOGY期刊下所有文献 > Luteinising hormones activate a factor(s) in testicular interstitial fluid which increases testicular vascular permeability.

Luteinising hormones activate a factor(s) in testicular interstitial fluid which increases testicular vascular permeability.

Abstract：

:The mechanism by which hCG increases the rat testicular vascular permeability was studied by injecting the testes with hCG (0.1-100 ng) together with testicular interstitial fluid (150 mul) or with the fluid alone (control) and measuring the uptake of i.v. injected [125I]hCG and the interstitial fluid volume in the testes. Both parameters were already increased with 1 ng of hCG and maxima were seen with 2 ng of hCG. The effect of hCG was not inhibited by injection of a 1000-fold excess of deglycosylated hCG together with hCG. No increase was seen after injection of 2 ng of hCG in saline or in rat serum. The response was specific to luteinising hormones since only rLH mimicked the effect of hCG, but deglycosylated hCG, rFSH or rat prolactin did not. Denaturation of the fluid or addition of serine protease inhibitor (p-aminobenzamidine) to the fluid prevented the effect of hCG. Treatment of the hCG-activated fluid with anti-hCG gamma-globulin Sepharose did not abolish the permeability effect of the fluid. This, and the finding that hCG is not catabolised during incubation in the fluid, suggests that hCG itself is not transformed to a vasoactive compound in the fluid. These results strongly suggest that luteinising hormones activate a factor(s) in rat testicular fluid which mediates their permeability effect. The putative factor(s) seems to be heat-sensitive with a molecular weight of over 10 000 Da.

journal_name

Mol Cell Endocrinol

journal_title

Molecular and cellular endocrinology

authors

Veijola M,Rajaniemi H

doi

10.1016/0303-7207(86)90138-3

subject

Has Abstract

pub_date

1986-05-01 00:00:00

pages

113-8

issue

2-3

eissn

0303-7207

issn

1872-8057

journal_volume

45

pub_type

杂志文章

相关文献

MOLECULAR AND CELLULAR ENDOCRINOLOGY文献大全
  • The role of the renin-angiotensin system in the development of insulin resistance in skeletal muscle.

    abstract：:The canonical renin-angiotensin system (RAS) involves the initial action of renin to cleave angiotensinogen to angiotensin I (ANG I), which is then converted to ANG II by the angiotensin converting enzyme (ACE). ANG II plays a critical role in numerous physiological functions, and RAS overactivity underlies many condi...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/j.mce.2012.04.011

    authors： Henriksen EJ,Prasannarong M

    更新日期：2013-09-25 00:00:00

  • Bioactive forms of vitamin D selectively stimulate the skin analog of the hypothalamus-pituitary-adrenal axis in human epidermal keratinocytes.

    abstract：:Ultraviolet radiation B stimulates both the production of vitamin D3 in the skin and the activation of the skin analog of the hypothalamic-pituitary-adrenal axis (HPA) as well as the central HPA. Since the role of vitamin D3 in the regulation of the HPA is largely unknown, we investigated the impact of 1,25(OH)2D3 and...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.mce.2016.08.006

    authors： Wierzbicka JM,Żmijewski MA,Piotrowska A,Nedoszytko B,Lange M,Tuckey RC,Slominski AT

    更新日期：2016-12-05 00:00:00

  • Seawater transfer down-regulates C-type natriuretic peptide-3 expression in prolactin-producing cells of Japanese eel: Negative correlation with plasma chloride concentration.

    abstract：:In euryhaline fishes, atrial and B-type natriuretic peptides are important hormones in hypo-osmoregulation, whereas osmoregulatory functions of C-type natriuretic peptides (CNPs) remain to be investigated. Although four CNP isoforms (CNP1-4) are mainly expressed in the brain, multiorgan expression of CNP3 was found in...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.mce.2020.110780

    authors： Katayama Y,Wong MK,Kusakabe M,Fujio M,Takahashi N,Yaguchi M,Tsukada T

    更新日期：2020-05-01 00:00:00

  • Cyclic AMP stimulates the gene expression of a non-selective cation channel, mNSC1, in pancreatic beta-cell line, MIN6.

    abstract：:Mouse non-selective cation channel 1 (mNSC 1) cDNA from mouse pancreatic beta-cell line, MIN6, have recently been cloned. Since the number of non-selective cation channel in pancreatic duct cells has been reported to increase 9-fold in 5 h incubation with cAMP, the effect of cAMP on the gene expression of mNSC1 in MIN...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/s0303-7207(99)00214-2

    authors： Satoh J,Kutsuwada K,Ohki G,Imai M,Kobayashi M,Suzuki M

    更新日期：2000-02-25 00:00:00

  • Hypothalamic mitochondrial abnormalities occur downstream of inflammation in diet-induced obesity.

    abstract：:Hypothalamic dysfunction is a common feature of experimental obesity. Studies have identified at least three mechanisms involved in the development of hypothalamic neuronal defects in diet-induced obesity: i, inflammation; ii, endoplasmic reticulum stress; and iii, mitochondrial abnormalities. However, which of these ...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.mce.2017.07.029

    authors： Carraro RS,Souza GF,Solon C,Razolli DS,Chausse B,Barbizan R,Victorio SC,Velloso LA

    更新日期：2018-01-15 00:00:00

  • Differential alternative splicing of PACAP receptor in pituitary cell subpopulations.

    abstract：:The capability of rat pituitary cells to express receptors for pituitary adenylate cyclase activating polypeptide (PACAP) and VIP was evaluated by binding studies and measurement of adenylate cyclase activity on whole gland preparations and by reverse transcriptase-polymerase chain reaction (TR-PCR) using specific pri...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/0303-7207(95)03626-i

    authors： Vertongen P,Velkeniers B,Hooghe-Peters E,Robberecht P

    更新日期：1995-09-22 00:00:00

  • Characterization and regulation of prolactin receptors in MA-10 Leydig cells.

    abstract：:The aim of this study is to further characterize the prolactin receptors (PRL-R) previously reported in the murine Leydig tumor MA-10 cell line, as well as to study their homologous and heterologous regulation. Two forms of PRL-R, a high and a low molecular weight form, were revealed by studies of covalent crosslinkin...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/s0303-7207(98)00134-8

    authors： Weiss-Messer E,Ber R,Amit T,Barkey RJ

    更新日期：1998-08-25 00:00:00

  • Epitope-tagged gonadotropin-releasing hormone receptors heterologously-expressed in mammalian (COS-1) and insect (Sf9) cells.

    abstract：:The molecular cloning and nucleotide sequencing of the gonadotropin-releasing hormone (GnRH) receptor represented an enhanced step in the experimental effort to understand this key molecule in the reproductive process at a cell and molecular level. A subsequent step in this broad effort is heterologous expression of t...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/s0303-7207(96)04003-8

    authors： Neill JD,Sellers JC,Musgrove LC,Duck LW

    更新日期：1997-03-28 00:00:00

  • Sequence of the bovine HDL-receptor (SR-BI) cDNA and changes in receptor mRNA expression during granulosa cell luteinization in vivo and in vitro.

    abstract：:Steroidogenic activity in the mature corpus luteum of most mammals depends upon provision of cholesterol from the circulating lipoproteins. In cattle, as in many species, high-density lipoprotein (HDL) is the major lipoprotein involved. The recent identification of the scavenger receptor SR-BI as an HDL-receptor allow...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/s0303-7207(97)00173-1

    authors： Rajapaksha WR,McBride M,Robertson L,O'Shaughnessy PJ

    更新日期：1997-10-31 00:00:00

  • Apoptosis induction by the glucocorticoid hormone dexamethasone and the calcium-ATPase inhibitor thapsigargin involves Bc1-2 regulated caspase activation.

    abstract：:The requirement for caspases (ICE-like proteases) were investigated in mediating apoptosis of WEHI7.2 mouse lymphoma cells in response to two death inducers with different mechanisms of action, the glucocorticoid hormone dexamethasone (DX) and the calcium-ATPase inhibitor thapsigargin (TG). Apoptosis induction by thes...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/s0303-7207(98)00051-3

    authors： McColl KS,He H,Zhong H,Whitacre CM,Berger NA,Distelhorst CW

    更新日期：1998-04-30 00:00:00

  • In vitro bioassay investigations of the endocrine disrupting potential of steviol glycosides and their metabolite steviol, components of the natural sweetener Stevia.

    abstract：:The food industry is moving towards the use of natural sweeteners such as those produced by Stevia rebaudiana due to the number of health and safety concerns surrounding artificial sweeteners. Despite the fact that these sweeteners are natural; they cannot be assumed safe. Steviol glycosides have a steroidal structure...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.mce.2016.03.005

    authors： Shannon M,Rehfeld A,Frizzell C,Livingstone C,McGonagle C,Skakkebaek NE,Wielogórska E,Connolly L

    更新日期：2016-05-15 00:00:00

  • Isolation and characterisation of calcineurin from adrenal cell cytoskeleton: identification of substrates for Ca2+-calmodulin-dependent phosphatase activity.

    abstract：:Ca2+-calmodulin-dependent protein phosphatase activity is found in cytoskeletons of Y-1 mouse adrenal and bovine fasciculata cells. The activity is inhibited by three inhibitors of calmodulin (trifluoperazine, W-7 and pimozide) with EC50 in the low micromolar range. Protein phosphatase activity is inhibited by vanadat...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/0303-7207(89)90078-6

    authors： Papadopoulos V,Brown AS,Hall PF

    更新日期：1989-05-01 00:00:00

  • Participation of NADPH 4 oxidase in thyroid regulation.

    abstract：:Different factors are involved in thyroid function and proliferation such as thyrotropin (TSH), insulin, growth factors, iodide, etc. TSH and IGF1/insulin increase proliferation rate and stimulate genes involved in thyroid differentiation. In the present study, we analyse the physiological regulation of NOX4 expressio...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.mce.2018.10.012

    authors： Oglio R,Salvarredi L,Rossich L,Copelli S,Pisarev M,Juvenal G,Thomasz L

    更新日期：2019-01-15 00:00:00

  • The intranuclear distribution of rat uterine estrogen receptors determined after nuclease treatment and chromatin fractionation.

    abstract：:The intranuclear locations at which rat uterine estrogen receptors interact with chromatin have been probed using digestions performed with DNAase I and micrococcal nuclease. Exposure to nuclease has been controlled to effect limited to extensive digestion of nuclear DNA under conditions which maintain the integrity o...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/0303-7207(82)90017-x

    authors： Pavlik EJ,Katzenellenbogen BS

    更新日期：1982-04-01 00:00:00

  • PC2/CPE-mediated pro-protein processing in tumor cells and its differentiated cells or tissues.

    abstract：:Pro-protein convertase-2 (PC2) and carboxypeptidase-E (CPE) proteins are two major members of the pro-protein convertases that involve in the maturation of protein precursor. By using PC2 activity, immunocytochemistry (ICC) and Western blot method, PC2, CPE and preproNPY protein expression levels were compared among m...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.mce.2009.01.020

    authors： Tang SS,Zhang JH,Liu HX,Li HZ

    更新日期：2009-05-06 00:00:00

  • Non-classical receptors for aldosterone in plasma membranes from pig kidneys.

    abstract：:Rapid, nongenomic in vitro effects of aldosterone on intracellular electrolytes, cell volume and the sodium-proton antiporter have been found in human mononuclear leukocytes (HML), as have related membrane receptors. In the present study, binding of 125I-labeled aldosterone to plasma membrane preparations from pig kid...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/0303-7207(94)90027-2

    authors： Christ M,Sippel K,Eisen C,Wehling M

    更新日期：1994-03-01 00:00:00

  • Differential expression of vitelline membrane outer layer protein 1: hormonal regulation of expression in the oviduct and in ovarian carcinomas from laying hens.

    abstract：:Vitelline membrane outer layer protein 1 (VMO1), a basic protein present in the outer layer of the vitelline membrane of eggs, plays essential roles in separating the yolk from the egg white and preventing infection from bacteria by forming a barrier of fibrous layers in avian eggs. Although VMO1 is expressed in the o...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.mce.2014.10.015

    authors： Lim W,Song G

    更新日期：2015-01-05 00:00:00

  • RAB7 and TSG101 are required for the constitutive recycling of unliganded EGFRs via distinct mechanisms.

    abstract：:Both constitutive and ligand-mediated membrane trafficking regulate Epidermal Growth Factor Receptor (EGFR) signaling. The constitutive endocytosis and recycling of the unliganded EGFR is a critical determinant of cell surface EGFR expression and the cell's sensitivity to ligands. We report that two proteins with esta...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.mce.2013.07.029

    authors： Rush JS,Ceresa BP

    更新日期：2013-12-05 00:00:00

  • Prevention of autoimmune diabetes and islet allograft rejection by beta cell expression of XIAP: Insight into possible mechanisms of local immunomodulation.

    abstract：:Overexpression of the X-linked inhibitor of apoptosis (XIAP) prevents islet allograft rejection. We constructed an adeno-associated virus expressing XIAP driven by the rat insulin promoter (dsAAV8-RIP-XIAP) for long-term beta-cell gene expression in vivo. Pancreatic delivery of dsAAV8-RIP-XIAP prevented autoimmune dia...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.mce.2018.05.015

    authors： Obach M,Hosseini-Tabatabaei A,Montane J,Wind K,Soukhatcheva G,Dai D,Priatel JJ,Orban PC,Verchere CB

    更新日期：2018-12-05 00:00:00

  • Peroxisome proliferator-activated receptor-α agonists modulate CXCL9 and CXCL11 chemokines in Graves' ophthalmopathy fibroblasts and preadipocytes.

    abstract：:Peroxisome proliferator-activated receptors (PPAR)α have been shown to exert immunomodulatory effects in autoimmune disorders; no study evaluated the effect of PPARα activation in Graves' ophthalmopathy (GO). We show the presence of PPARα, δ and γ in GO fibroblasts and preadipocytes. PPARα activators have a potent inh...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.mce.2011.11.001

    authors： Antonelli A,Ferrari SM,Frascerra S,Ruffilli I,Gelmini S,Minuto M,Pupilli C,Miccoli P,Sellari-Franceschini S,Ferrannini E,Fallahi P

    更新日期：2012-02-26 00:00:00

  • Localization and expression of low-density lipoprotein receptor, steroidogenic acute regulatory protein, cytochrome P450 side-chain cleavage and P450 17-alpha-hydroxylase/C17-20 lyase in developing swine follicles: in situ molecular hybridization and immu

    abstract：:The present study utilizes in situ molecular hybridization and immunocytochemistry to investigate the follicular localization and expression of four thematically related sterol-metabolizing genes; low-density lipoprotein (LDL) receptor, steroidogenic acute regulatory protein (StAR), cytochrome P450 side-chain cleavage...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/s0303-7207(00)00332-4

    authors： Garmey JC,Guthrie HD,Garrett WM,Stoler MH,Veldhuis JD

    更新日期：2000-12-22 00:00:00

  • AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer.

    abstract：:Endometrial cancer is the most common malignancy of the female genital tract. Its incidence correlates with prolonged estrogen stimulation unopposed by progesterone or synthetic progestins. Estrogen and progestin action is regulated at the pre-receptor level, by interconversion of active hormones (estradiol (E2), prog...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.mce.2005.10.009

    authors： Rizner TL,Smuc T,Rupreht R,Sinkovec J,Penning TM

    更新日期：2006-03-27 00:00:00

  • Dual effects of nitric oxide on meiotic maturation of mouse cumulus cell-enclosed oocytes in vitro.

    abstract：:The present experiment used cultured mouse cumulus cell-enclosed oocytes (CEOs) and denuded oocytes (DOs) to study the function of nitric oxide (NO) in mouse oocyte meiotic maturation. Either positive or negative actions of NO on meiotic maturation has been observed when CEOs or DOs were cultured for 24 h in a medium ...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/s0303-7207(03)00213-2

    authors： Bu S,Xia G,Tao Y,Lei L,Zhou B

    更新日期：2003-09-30 00:00:00

  • Progestin-inducible EDD E3 ubiquitin ligase binds to α4 phosphoprotein to regulate ubiquitination and degradation of protein phosphatase PP2Ac.

    abstract：:Mammalian α4 phosphoprotein binds to the protein phosphatase 2A catalytic subunit (PP2Ac) to regulate PP2A activity, and to poly(A)-binding protein (PABP) and progestin-inducible EDD E3 ubiquitin ligase. This study showed induction of the EDD protein by progesterone, 17β-estradiol and prolactin in breast cancer cells....

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/j.mce.2013.09.033

    authors： McDonald WJ,Thomas LN,Koirala S,Too CKL

    更新日期：2014-01-25 00:00:00

  • Enhanced activity of the cardiac endocrine system during right ventricular hypertrophy.

    abstract：:In a model of pulmonary hypertension induced by a single injection of monocrotaline (MCT), we observed a time-dependent right ventricular hypertrophy, which became apparent in treated rats 21 days after administration of MCT and progressed through day 45. Associated with this right ventricular hypertrophy were time-de...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/0303-7207(89)90011-7

    authors： Oehlenschlager WF,Kurtz DT,Baron DA,Currie MG

    更新日期：1989-04-01 00:00:00

  • Early environmental regulation of hippocampal glucocorticoid receptor gene expression: characterization of intracellular mediators and potential genomic target sites.

    abstract：:Environmental conditions in early life permanently alter the development of glucocorticoid receptor gene expression in the hippocampus and hypothalamic-pituitary-adrenal responses to acute or chronic stress. In part, these effects can involve an activation of ascending serotonergic pathways and subsequent changes in t...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/s0303-7207(01)00635-9

    authors： Weaver IC,La Plante P,Weaver S,Parent A,Sharma S,Diorio J,Chapman KE,Seckl JR,Szyf M,Meaney MJ

    更新日期：2001-12-20 00:00:00

  • Relationship between renin mRNA and renin secretion in adrenalectomized, salt-depleted, or converting enzyme inhibitor-treated rats.

    abstract：:Renin secretion was stimulated in rats by adrenalectomy (ADX), by treatment with the converting enzyme inhibitor enalapril (MK 421), or by feeding a low salt diet plus furosemide treatment (FUR). Relative amounts of renin mRNA were measured by densitometric Northern blot analysis using a 32P-labeled 700 bp mouse subma...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/0303-7207(87)90020-7

    authors： Ludwig G,Ganten D,Murakami K,Fasching U,Hackenthal E

    更新日期：1987-04-01 00:00:00

  • Mouse insulin-like growth factor binding protein-6: expression, purification, characterization and histochemical localization.

    abstract：:The mitogenic and metabolic activities of insulin-like growth factors (IGF) are modulated by a family of six high affinity IGF binding proteins (IGFBPs). This study describes the expression of the mouse IGFBP-6 which is unique among IGFBPs in its preferential binding of IGF II, in insect cells using the baculovirus sy...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/s0303-7207(97)00233-5

    authors： Putzer P,Breuer P,Götz W,Gross M,Kübler B,Scharf JG,Schuller AG,Hartmann H,Braulke T

    更新日期：1998-02-01 00:00:00

  • Puberty-related influences on brain development.

    abstract：:Puberty is a time of striking changes in cognition and behavior. To indirectly assess the effects of puberty-related influences on the underlying neuroanatomy of these behavioral changes we will review and synthesize neuroimaging data from typically developing children and adolescents and from those with anomalous hor...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章,评审

    doi：10.1016/j.mce.2006.04.016

    authors： Giedd JN,Clasen LS,Lenroot R,Greenstein D,Wallace GL,Ordaz S,Molloy EA,Blumenthal JD,Tossell JW,Stayer C,Samango-Sprouse CA,Shen D,Davatzikos C,Merke D,Chrousos GP

    更新日期：2006-07-25 00:00:00

  • Properties of a cell-culture line derived from lymphosarcoma P1798.

    abstract：:A cell culture line has been derived from lymphosarcoma P1798. Cells will not divide in the prescence of 10(-8) M dexamethasone. Half-maximal inhibition of proliferation occurs at about 10(-9) M. Half-maximal inhibition of [3H] thymidine incorporation occurs at somewhat higher concentrations of dexamethasone. When cel...

    journal_title：Molecular and cellular endocrinology

    pub_type： 杂志文章

    doi：10.1016/0303-7207(80)90121-5

    authors： Thompson EA Jr

    更新日期：1980-02-01 00:00:00