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Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322.

Abstract：

:I have determined the nucleotide sequence of the ampicillin resistance gene of pBR322, an Escherichia coli plasmid that encodes a penicillin beta-lactamase. This gene codes for a protein of 286 amino acid residues. The first 23 amino acids presumably form a signal for secretion, because they do not appear in the mature enzyme, whose partial amino acid sequence has been determined independently.

journal_name

Proc Natl Acad Sci U S A

journal_title

Proceedings of the National Academy of Sciences of the United States of America

authors

Sutcliffe JG

doi

10.1073/pnas.75.8.3737

subject

Has Abstract

pub_date

1978-08-01 00:00:00

pages

3737-41

issue

8

eissn

0027-8424

issn

1091-6490

journal_volume

75

pub_type

杂志文章

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