Abstract：
:In primary cultures of ovine thyroid cells, TSH induced the expression of several differentiated functions including the formation of follicles, and synthesis and storage of iodinated thyroglobulin in the follicular lumen. In the present report, these follicles were shown by transmission (TEM) and scanning electron microscopy (SEM) to be intact, comprised of two or more cells and to possess numerous microvilli on the inner cell membranes facing the follicular lumen. The TSH-induced formation of follicles was reversible and dynamic, with the kinetics of formation preceding that of iodination. The follicles were further demonstrated to be functional in terms of thyroglobulin storage and iodination.
journal_name
Exp Cell Resjournal_title
Experimental cell researchauthors
Mak WW,Errick JE,Chan RC,Eggo MC,Burrow GNdoi
10.1016/0014-4827(86)90031-5subject
Has Abstractpub_date
1986-06-01 00:00:00pages
311-22issue
2eissn
0014-4827issn
1090-2422journal_volume
164pub_type
杂志文章abstract：:Zinc is found in a variety of organisms and has been suggested to be essential for many cellular functions. We report here that zinc ions (Zn2+) have a specific and striking effect on cell differentiation in the simple eukaryote, Dictyostelium discoideum. In its asexual reproduction phase, solitary cells gather to for...
journal_title：Experimental cell research
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journal_title：Experimental cell research
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更新日期：2010-05-15 00:00:00
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journal_title：Experimental cell research
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journal_title：Experimental cell research
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journal_title：Experimental cell research
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journal_title：Experimental cell research
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