Prolactin receptors in the male Rana esculenta.


:The binding of 125I-labeled ovine prolactin (oPRL) to membrane preparations of several tissues from the male green frog, Rana esculenta, collected during the year is reported. PRL binding to kidney fractions was generally high (range 5-45%). A maximum was observed in the month of October, whereas the lowest value was found during the summer season. The binding to skin fractions was equally high (range 5-25%) and the annual profile parallels that of renal fractions. In the liver, a lower specific binding (range 3-4%) occurred consistently during the year, whereas no detectable binding was found in the muscle. The 125I-oPRL binding was inhibited by oPRL and oGH but not by oFSH or oLH. Scatchard analysis gave dissociation constants of 0.4-1 x 10(-10) M and binding capacity of about 20 fmol/mg of membrane proteins was observed in both the skin and kidney fractions. No receptor sites were detectable in 30-day hypophysectomized animals. The administration of oPRL or a crude homogenate of the frog hypophysis induced the appearance of specific PRL binding. Testosterone is able to restore prolactin binding in hypophysectomized animals, as PRL treatment does.


Gen Comp Endocrinol


d'Istria M,Fasano S,Delrio G




Has Abstract


1987-10-01 00:00:00












  • Effects of GnRH-associated peptide and its component peptides on prolactin secretion from the tilapia pituitary in vitro.

    abstract::The rostral pars distalis (RPD), containing mainly prolactin (PRL)-secreting cells, of the pituitary from immature and mature tilapia was incubated for 16 hr at 27 degrees in hypoosmotic medium (300 mOsm/kg) in the presence (10(-8) and 10(-11) M) or absence of the human GnRH-associated peptide (GAP) molecule, a potent...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Planas J,Bern HA,Millar RP

    更新日期:1990-03-01 00:00:00

  • Immunocytochemical and histological differences in the interrenal axis of feral brown trout, Salmo trutta, in metal-contaminated waters.

    abstract::There are more CRH-like immunoreactive neurons in the preoptic nucleus and nucleus lateralis tuberis in the brain of feral brown trout, Salmo trutta, living in cadmium- and zinc-contaminated regions of the Eagle River than in fish from an uncontaminated control site. Histological analyses revealed that interrenal cell...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Norris DO,Felt SB,Woodling JD,Dores RM

    更新日期:1997-12-01 00:00:00

  • Reverse genetics tools in zebrafish: a forward dive into endocrinology.

    abstract::The zebrafish is a powerful genetic model organism. In recent years, zebrafish has been increasingly used to model human diseases. Due to a number of recent technological advancements, the genetic tool box is now also stocked with sophisticated transgenic and reverse genetic tools. Here, we focus on both commonly used...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Sugano Y,Neuhauss SC

    更新日期:2013-07-01 00:00:00

  • Growth and endocrine effects of recombinant bovine growth hormone treatment in non-transgenic and growth hormone transgenic coho salmon.

    abstract::To examine the relative growth, endocrine, and gene expression effects of growth hormone (GH) transgenesis vs. GH protein treatment, wild-type non-transgenic and GH transgenic coho salmon were treated with a sustained-release formulation of recombinant bovine GH (bGH; Posilac). Fish size, specific growth rate (SGR), a...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Raven PA,Sakhrani D,Beckman B,Neregård L,Sundström LF,Björnsson BT,Devlin RH

    更新日期:2012-05-15 00:00:00

  • Absence of an effect of naloxone, an opioid antagonist, on luteinizing hormone release in vivo and luteinizing hormone-releasing hormone I release in vitro in intact, castrated, and food restricted cockerels.

    abstract::The possibility that the tonic secretion of luteinizing hormone (LH) and chicken luteinizing hormone-releasing hormone I (LHRH-I) is regulated by an inhibitory action of endogenous opioid peptides was investigated in cockerels using the opiate receptor antagonist, naloxone. Baseline concentrations of plasma LH in the ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Lal P,Sharp PJ,Dunn IC,Talbot RT

    更新日期:1990-02-01 00:00:00

  • Regulation of growth hormone (GH) receptor (GHR1 and GHR2) mRNA level by GH and metabolic hormones in primary cultured tilapia hepatocytes.

    abstract::Growth hormone (GH) regulates essential physiological functions in teleost fishes, including growth, metabolism, and osmoregulation. Recent studies have identified two clades of putative receptors for GH (GHR1 clade and GHR2 clade) in fishes, both of which are highly expressed in the liver. Moreover, the liver is an i...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Pierce AL,Breves JP,Moriyama S,Uchida K,Grau EG

    更新日期:2012-10-01 00:00:00

  • Inhibition of cortisol metabolism by 17alpha,20beta-P: mechanism mediating semelparity in salmon?

    abstract::In vitro experiments were conducted to test the hypothesis that 17alpha,20beta-dihydroxy-4-prengnen-3-one (17,20-P) regulates cortisol metabolism in Pacific salmon. In both rainbow trout and coho salmon, cortisol metabolism was significantly higher in the kidney compared to the liver. The rainbow trout kidney converte...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Barry TP,Marwah A,Nunez S

    更新日期:2010-01-01 00:00:00

  • Thyroid hormones and learning-associated neuroplasticity.

    abstract::Thyroid hormones (THs) are crucial for brain development and maturation in all vertebrates. Especially during pre- and perinatal development, disruption of TH signaling leads to a multitude of neurological deficits. Many animal models provided insight in the role of THs in brain development, but specific data on how t...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章,评审


    authors: Raymaekers SR,Darras VM

    更新日期:2017-06-01 00:00:00

  • Sex differentiation in the hagfish Eptatretus stouti.

    abstract::A detailed study was made of sex differentiation in three anteroposteriorly distributed body regions of the long gonadal fold in young Pacific hagfish (Eptatretus stouti) from 12.4 to 45 cm in length. In general, the posterior region, adjacent to the cloaca, remained undifferentiated, and only in specimens more than 2...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Gorbman A

    更新日期:1990-02-01 00:00:00

  • Anandamide modulates the expression of GnRH-II and GnRHRs in frog, Rana esculenta, diencephalon.

    abstract::In the hypothalamus, endocannabinoids affect neuroendocrine activity by means of Gonadotropin-Releasing-Hormone-I (GnRH-I) inhibition. Since most vertebrates, human included, possess at least two GnRH molecular forms, the aim of this work was to investigate the effect of endocannabinoids on GnRH molecular forms other ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Chianese R,Ciaramella V,Fasano S,Pierantoni R,Meccariello R

    更新日期:2011-09-15 00:00:00

  • In vitro effects of ACTH on interrenal corticosteroidogenesis during early larval development in rainbow trout.

    abstract::Interrenal tissue from embryonic and larval rainbow trout (Oncorhynchus mykiss) was cultured in vitro and exposed to various doses of adrenocorticotropin (ACTH) to document the ontogeny of interrenal responsiveness to tropic stimulation. Resting and acute stress-induced changes in whole-body cortisol levels in vivo we...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Barry TP,Ochiai M,Malison JA

    更新日期:1995-09-01 00:00:00

  • Cloning and differential expression of steroid 5 alpha-reductase type 1 (Srd5a1) and type 2 (Srd5a2) from the Harderian glands of hamsters.

    abstract::In hamsters, the Harderian glands (HGs) exhibit a marked sexual dimorphism which is thought to depend on dihydrotestosterone (DHT); however, it is unclear whether hamster HGs contain one or more 5 alpha-reductases and whether these enzymes are differentially expressed in males and females. In this study, we isolated s...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Ramos L,Chávez B,Vilchis F

    更新日期:2010-04-01 00:00:00

  • A novel thyroid stimulating hormone beta-subunit isoform in human pituitary, peripheral blood leukocytes, and thyroid.

    abstract::Thyroid stimulating hormone (TSH) is produced by the anterior pituitary and is used to regulate thyroid hormone output, which in turn controls metabolic activity. Currently, the pituitary is believed to be the only source of TSH used by the thyroid. Recent studies in mice from our laboratory have identified a TSHbeta ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Schaefer JS,Klein JR

    更新日期:2009-07-01 00:00:00

  • Arginine vasotocin and mesotocin levels in theca and granulosa layers of the ovary during the oviposition cycle in hens (Gallus domesticus).

    abstract::Neurohypophysial hormones in mammals are synthesized by the ovary and may influence reproductive function. Although arginine vasotocin (AVT) can induce premature oviposition in chickens, the gonadal content of AVT or mesotocin (MT) has not been examined in this species. Ovarian follicles were removed 2 hr before ovipo...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Saito N,Kinzler S,Koike TI

    更新日期:1990-07-01 00:00:00

  • Regulation of prothoracicotropic hormone release by juvenile hormone in the penultimate and last instar larvae of Mamestra brassicae.

    abstract::The penultimate instar larvae of Mamestra brassicae have one ecdysteroid peak 2 days after ecdysis which induces larval ecdysis. Allatectomy deleted this peak and caused a larger peak 7 days later just before precocious pupation, in a pattern similar to the ecdysteroid titer of the last instar. Application of juvenile...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Hiruma K

    更新日期:1986-08-01 00:00:00

  • Tissue-specific regulation of the growth hormone/insulin-like growth factor axis during fasting and re-feeding: Importance of muscle expression of IGF-I and IGF-II mRNA in the tilapia.

    abstract::The effects of prolonged nutrient restriction (fasting) and subsequent restoration (re-feeding) on the growth hormone (GH)/insulin-like growth factor (IGF) axis were investigated in the tilapia (Oreochromis mossambicus). Mean weight and specific growth rate declined within 1 week in fasted fish, and remained lower tha...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Fox BK,Breves JP,Davis LK,Pierce AL,Hirano T,Grau EG

    更新日期:2010-05-01 00:00:00

  • Investigations of endocrine cells in the gastrointestinal tract and pancreas during the metamorphosis of an anuran (Alytes obstetricans L.): histochemical detection of APUD cells.

    abstract::Endocrine cells were detected at premetamorphosis, prometamorphosis, climax, and juvenile stages using an amine-inducing fluorescence technique with or without previous L-3,4-dihydroxyphenylalanine (L-DOPA) treatment. At premetamorphosis, serotonin cells exhibited yellow fluorescence in the gut primary epithelium of t...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: L'Hermite A,Hourdry J,Ferrand R

    更新日期:1988-03-01 00:00:00

  • Kisspeptin: a new neuronal target of primer pheromones in the control of reproductive function in mammals.

    abstract::Pheromones are known to trigger either short-term behavioral responses, usually referred to as "releaser effects", or more long-term physiological changes, known as "primer effects", which especially affect reproductive function at the level of the gonadotrope axis. The precise mechanisms through which pheromones inte...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章,评审


    authors: Jouhanneau M,Szymanski L,Martini M,Ella A,Keller M

    更新日期:2013-07-01 00:00:00

  • Immunoreactive gonadotropin-releasing hormone (GnRH) is detected only in the form of chicken GnRH-II within the brain of the green anole, Anolis carolinensis.

    abstract::The presence of multiple forms of gonadotropin-releasing hormone (GnRH) within a single brain is common among vertebrate species. In previous studies of reptiles, two forms of GnRH were isolated from the brain of alligators and the primary structure was determined to be that of chicken (c)GnRH-I and cGnRH-II. GnRH has...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Lescheid DW,Rosen GJ,Bridge AE,Jones RE,Warby CM,Sherwood NM

    更新日期:1997-11-01 00:00:00

  • Associations between social behaviour and adrenal activity in female Barbary macaques: consequences of study design.

    abstract::Faecal glucocorticoid metabolite (fGCM) concentrations have been used to evaluate adrenal activity in a variety of species; including as an indicator of the physiological response to social stress. However, across studies, the relationships between dominance rank, social behaviours and adrenal responses can be inconsi...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Edwards KL,Walker SL,Bodenham RF,Ritchie H,Shultz S

    更新日期:2013-06-01 00:00:00

  • Plasma corticosterone in wild starlings (Sturnus vulgaris) immediately following capture and in relation to body weight during the annual cycle.

    abstract::Free-living starlings (Sturnus vulgaris) were caught by mist netting. Blood samples were taken from them between 20 sec and 4 min after capture and assayed for corticosterone. Before 1 min corticosterone levels were constant (10.3 nmol litre-1) but after 1 min they increased rapidly (27.0 +/- 3.6 nmol litre-1 min-1). ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Dawson A,Howe PD

    更新日期:1983-08-01 00:00:00

  • The transcripts of CRF and CRF receptors under fasting stress in Dabry's sturgeon (Acipenser dabryanus Dumeril).

    abstract::Dabry's sturgeon (Acipenser dabryanus Dumeril, 1868) belongs to Sturgeon and is distributed throughout the mainstream of the upper Yangtze River. While there is little research onphysiological mechanism of Dabry's sturgeon, such as feeding regulation by the CRF system. At present, CRF is thought to regulate feeding vi...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Qi J,Tang N,Wu Y,Chen H,Wang S,Wang B,Xu S,Wang M,Zhang X,Chen D,Zhou B,Li Z

    更新日期:2019-09-01 00:00:00

  • Corticosterone levels during post-natal development in captive American kestrels (Falco sparverius).

    abstract::We investigated post-natal development of the adrenocortical stress-response system in captive American kestrels (Falco sparverius) by measurements of baseline and stress-induced levels of corticosterone at ages 10, 16, 22, and 28 days post-hatching. Baseline levels of corticosterone increased significantly during pos...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Love OP,Bird DM,Shutt LJ

    更新日期:2003-02-01 00:00:00

  • Development and application of an ELISA for a sex pheromone released by the male sea lamprey (Petromyzon marinus L.).

    abstract::An enzyme-linked immunosorbent assay (ELISA) has been developed for a conjugated bile acid, 7alpha,12alpha,24-trihydroxy-5alpha-cholan-3-one 24-sulfate (commonly referred to as 3-keto petromyzonol sulfate [3kPZS]), a pheromone released by reproductively mature male sea lampreys to attract sexually mature females. A po...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Yun SS,Scott AP,Siefkes MJ,Li W

    更新日期:2002-12-01 00:00:00

  • Molecular evolution of adiponectin in Carnivora and its mRNA expression in relation to hepatic lipidosis.

    abstract::Adiponectin is a novel adipocyte-derived hormone with low circulating concentrations and/or mRNA expression in obesity and non-alcoholic fatty liver disease (NAFLD). The adiponectin mRNA of several Carnivora species was sequenced to enable further gene expression studies in this clade with potential experimental speci...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Nieminen P,Rouvinen-Watt K,Kapiainen S,Harris L,Mustonen AM

    更新日期:2010-09-15 00:00:00

  • High temperature increases the gsdf expression in masculinization of genetically female Japanese flounder (Paralichthys olivaceus).

    abstract::In teleosts, sex is plastic and is influenced by environmental factors. Elevated temperatures have masculinizing effects on the phenotypic sex of certain sensitive species. In this study, we reared genetic XX Japanese flounder at a high temperature (27.5 ± 0.5 °C) and obtained a population of sex-reversal XX males (ma...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Yang Y,Liu Q,Xiao Y,Xu S,Wang X,Yang J,Song Z,You F,Li J

    更新日期:2019-04-01 00:00:00

  • Increase in ovarian alpha-inhibin gene expression and plasma immunoreactive inhibin level is correlated with a decrease in ovulation rate in the domestic hen.

    abstract::This study was designed to examine the relationship among ovulation rate, inhibin alpha-subunit gene expression, and plasma immunoreactive inhibin levels between hens laying at a high ovulation rate and hens laying at a low ovulation rate. A porcine inhibin alpha-subunit cDNA was used to examine the expression of inhi...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Wang SY,Johnson PA

    更新日期:1993-07-01 00:00:00

  • Seasonal and population variation in male testosterone levels in breeding orange-crowned warblers (Vermivora celata).

    abstract::Comparative hormone studies can reveal how physiology underlies life history variation. Here, we examined seasonal variation in plasma testosterone concentration between populations of male orange-crowned warblers (Vermivora celata) breeding in Fairbanks, Alaska (V. c. celata) and on Santa Catalina Island, California ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Horton BM,Yoon J,Ghalambor CK,Moore IT,Scott Sillett T

    更新日期:2010-09-15 00:00:00

  • Use of a GnRH agonist to suppress testosterone in wild male Hawaiian monk seals (Monachus schauinslandi).

    abstract::A gonadotropin-releasing hormone (GnRH) agonist, d-Trp6-LHRH, was evaluated for its effectiveness in reducing circulating testosterone concentrations in wild Hawaiian monk seals (Monachus schauinslandi). Twenty-eight adult male seals were randomly divided into three groups: 10 were captured and treated with 7.5 mg of ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Atkinson S,Ragen TJ,Gilmartin WG,Becker BL,Johanos TC

    更新日期:1998-11-01 00:00:00

  • Dopaminergic and enkephalinergic involvement in the regulation of blood glucose in the red swamp crayfish, Procambarus clarkii.

    abstract::In in vivo experiments injection of dopamine (DA) or leucine enkephalin (L-Enk) produced hypoglycemia in intact red swamp crayfish, Procambarus clarkii. In contrast, neither compound had a significant effect on the circulating glucose concentration in eyestalkless individuals. With intact crayfish spiperone, a DA rece...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章


    authors: Sarojini R,Nagabhushanam R,Fingerman M

    更新日期:1995-01-01 00:00:00