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The complete amino acid sequences of alpha subunits of chum salmon gonadotropins.

Abstract：

:The complete amino acid sequences of alpha subunits of chum salmon (Oncorhynchus keta) gonadotropins (GTHs), GTH I and GTH II, were determined. Subunits were separated by reversed-phase high-performance liquid chromatography. Two alpha subunits, I alpha 1 and I alpha 2, were obtained from GTH I, whereas only one alpha subunit was obtained from GTH II. Sequence analysis revealed that GTH I alpha 2 is identical to GTH II alpha, but distinct from GTH I alpha 1. The I alpha 1 and II alpha consist of 95 and 92 amino acid residues, respectively. GTH I alpha 1 has 72% sequence identity with GTH I alpha 2. The two alpha subunits show approximately 65% sequence identity with bovine alpha subunit. This is the first finding of two chemically distinct alpha subunits from one species.

journal_name

Gen Comp Endocrinol

journal_title

General and comparative endocrinology

authors

Itoh H,Suzuki K,Kawauchi H

doi

10.1016/0016-6480(90)90047-p

subject

Has Abstract

pub_date

1990-04-01 00:00:00

pages

56-65

issue

1

eissn

0016-6480

issn

1095-6840

pii

0016-6480(90)90047-P

journal_volume

78

pub_type

杂志文章

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