Abstract:
:The role of the pituitary in regulating interrenal activity in coho salmon (Oncorhynchus kisutch) was examined using short- (1 week) or long- (10 week) term hypophysectomized (Hx) animals. In experiments in which Hx animals were injected with ovine growth hormone (oGH), triiodothyronine, or vehicle, plasma cortisol was significantly lower (close to non-detectable, 1 ng/ml) in vehicle-injected or hormone-treated short- and long-term Hx animals compared to vehicle-treated sham-operated (SO animals). Treatment of long-term Hx animals with oGH led to a significant increase in plasma cortisol, in comparison to other Hx groups. Interrenal responsiveness to ACTH or cAMP was not consistently affected by hypophysectomy or hormone treatment. Pregnenolone-supported cortisol production by tissue from Hx groups was at least as great as that by tissue from SO animals; production by tissue from GH-treated, long-term Hx animals was significantly greater than that by tissue from Hx or SO animals. Similar experiments utilizing handling stress (handling and anesthesia) instead of hormone injection as a variable revealed that the response of tissue from Hx animals to ACTH or cAMP was significantly reduced in the absence of handling in comparison with SO animals. However, utilization of pregnenolone as a substrate by tissue from Hx animals was no different from that by tissue from SO animals and was independent of handling. These results indicate that the maintenance of the steroid-biosynthetic pathway is pituitary independent. The decrease in tissue responsiveness to ACTH or cAMP in undisturbed Hx animals may be partially attributable to: (1) the absence of nonpituitary/nonpituitary-mediated factors that are stimulated by handling and which probably upregulate ACTH receptors and mediating systems; and/or (2) to the presence of inhibitory factors which are decreased after handling.
journal_name
Gen Comp Endocrinoljournal_title
General and comparative endocrinologyauthors
Young Gdoi
10.1006/gcen.1993.1179subject
Has Abstractpub_date
1993-12-01 00:00:00pages
428-38issue
3eissn
0016-6480issn
1095-6840pii
S0016-6480(83)71179-2journal_volume
92pub_type
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journal_title:General and comparative endocrinology
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journal_title:General and comparative endocrinology
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journal_title:General and comparative endocrinology
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2019.113347
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journal_title:General and comparative endocrinology
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journal_title:General and comparative endocrinology
pub_type: 杂志文章,评审
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2016.05.005
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
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abstract::Methyl farnesoate (MF) stimulation of ecdysteroid secretion by Y-organs of the crab, Cancer magister, is demonstrated. Isolated Y-organs that were incubated with a mandibular organ (MO) secreted significantly higher levels of ecdysteroids into the medium when compared to those incubated in the absence of a MO. MOs sec...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1993.1050
更新日期:1993-03-01 00:00:00
abstract::The effects of prolonged nutrient restriction (fasting) and subsequent restoration (re-feeding) on the growth hormone (GH)/insulin-like growth factor (IGF) axis were investigated in the tilapia (Oreochromis mossambicus). Mean weight and specific growth rate declined within 1 week in fasted fish, and remained lower tha...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2009.11.012
更新日期:2010-05-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.2001.7728
更新日期:2001-12-01 00:00:00
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journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.2000.7599
更新日期:2001-03-01 00:00:00
abstract::The total cortisol content in tilapia was 55 pg immediately following fertilization, then decreased abruptly and maintained a lower level of 10-20 pg until hatching; after hatching the cortisol content increased to 50 pg by the 7th day. Fertilized eggs were incubated in either 32% saltwater or fresh water and sampled ...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1993.1168
更新日期:1993-11-01 00:00:00
abstract::The capacity for early life environmental stressors to induce programming effects on the endocrine stress response in fish is largely unknown. In this study we determined the effects of high environmental ammonia (HEA) exposure on the stress response in larval zebrafish, assessed the tolerance of embryonic and larval ...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2017.09.024
更新日期:2017-12-01 00:00:00
abstract::In this study, we compare the ontogenic patterns for thyroid hormones, growth hormone (GH), and insulin-like growth factor-I (IGF-I) in altricial European starlings and precocial Japanese quail and examine the effects of feed restriction on these species. The most marked difference in development between the altricial...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1996.0033
更新日期:1996-03-01 00:00:00