Abstract：
:This work investigated the extent to which constituent proportions of fast- and slow-twitch muscle units determine whole muscle contractile properties. We employed several self- and cross-reinnervation models using synergistic homogeneous and heterogeneous muscles. By comparing the present data with previously published single-unit studies on the same animals, we confirmed that the whole muscle data provide a weighted ensemble of single-unit effects. They corroborate conclusions based upon single-unit data concerning the proportions of fast- and slow-twitch units, the degree of recovery, and the alteration of force- and speed-related properties of muscle by nerve. In particular, the shape of the whole muscle isometric twitch was a reliable indicator of the relative proportions of fast- and slow-twitch motor units in the muscle. The half-rise time was an indicator of the presence or absence of fast units, and the half-relaxation time was an indicator of the presence of slow units.
journal_name
Exp Neuroljournal_title
Experimental neurologyauthors
Foehring RC,Sypert GW,Munson JBdoi
10.1016/0014-4886(88)90048-9subject
Has Abstractpub_date
1988-09-01 00:00:00pages
366-73issue
3eissn
0014-4886issn
1090-2430journal_volume
101pub_type
杂志文章abstract：:A previous study of our group demonstrated that movement performance induced by dopamine agonist drugs in hemiparkinsonian rats unilaterally lesioned with 6-hydroxydopamine (6-OHDA), governs the occurrence of a sensitized motor response to a subsequent dopaminergic challenge (priming model). In the present study, we e...
journal_title：Experimental neurology
pub_type： 杂志文章
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更新日期：2013-09-01 00:00:00
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journal_title：Experimental neurology
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更新日期：1985-01-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
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abstract：:Parkinson's disease (PD) is an aging-associated neurodegenerative disorder with progressive pathology involving the loss of midbrain dopaminergic neurons. Neurotrophic factors are promising for PD gene therapy; they are integrally involved in the development of the nigrostriatal system. Cerebral dopamine neurotrophic ...
journal_title：Experimental neurology
pub_type： 杂志文章
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journal_title：Experimental neurology
pub_type： 杂志文章
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/0014-4886(85)90194-3
更新日期：1985-05-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
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更新日期：2012-01-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2013.11.005
更新日期：2014-01-01 00:00:00
abstract：:It is clear that there are events which occur in response to neuromuscular activity that are essential to maintain normal muscle properties. Two factors though to influence muscle contractile properties are tension and electrical activity. To study these variables the hind limbs of 10 postpubertal female Sprague-Dawle...
journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/0014-4886(87)90226-3
更新日期：1987-06-01 00:00:00
abstract：:Infant, juvenile, and adult brain growth is modulated by corticosterone. This study was designed to determine whether such modulation is confined to certain specific brain areas, and if the pattern of growth revealed is consistent across strains of rats. Young female Sprague-Dawley-derived rats were either adrenalecto...
journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/0014-4886(88)90229-4
更新日期：1988-12-01 00:00:00
abstract：:In peripheral neuropathy (PN), dorsal column (DC) fibers that synapse in the nucleus gracilis (NuGr) mediate expression of mechanical allodynia and have increased expression of brain-derived neurotrophic factor (BDNF). Neurotrophins (NTs) are implicated in pathology or repair in PN. To assess NTs in the NuGr in PN, mR...
journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2004.03.011
更新日期：2004-06-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1006/exnr.2002.7924
更新日期：2002-07-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2005.07.019
更新日期：2005-11-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2015.06.023
更新日期：2015-09-01 00:00:00
abstract：:Dopaminergic (DAergic) hypofunction in the medial prefrontal cortex (mPFC) has been implicated in the negative and cognitive symptoms of schizophrenia and is regulated by serotonergic (5-HTergic) neurons in the dorsal raphe nucleus (DRN). The lateral habenula (LHb) is a key element in controlling DRN 5-HT neurons. We ...
journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2019.05.005
更新日期：2019-08-01 00:00:00
abstract：:Although ciliary neurotrophic factor (CNTF) has been shown to promote the survival of magnocellular neurons when applied exogenously to explants of the paraventricular and supraoptic nuclei (SON) in vitro, little is known regarding its expression or regulation in the adult magnocellular neurosecretory system (MNS) fol...
journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2005.09.009
更新日期：2006-01-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
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journal_title：Experimental neurology
pub_type： 杂志文章
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/0014-4886(90)90012-h
更新日期：1990-04-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2004.04.021
更新日期：2004-08-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2006.11.003
更新日期：2007-03-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2009.12.011
更新日期：2010-03-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1006/exnr.2000.7362
更新日期：2000-05-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2012.01.020
更新日期：2012-04-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/0014-4886(86)90103-2
更新日期：1986-11-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2005.12.027
更新日期：2006-04-01 00:00:00
abstract：:MK-801, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, was tested for anticonvulsant effects in rats using two seizure models, coadministration of lithium and pilocarpine and administration of a high dose of pilocarpine alone. Three major results are reported. First, pretreatment with MK-801 produce...
journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/0014-4886(89)90091-5
更新日期：1989-11-01 00:00:00
