Increased glucose use in the hypoglossal nucleus after hypoglossal nerve transection in aged rats.

Abstract:

:We used [2-14C]deoxyglucose as a marker of increased metabolism of the hypoglossal nucleus after transection of its nerve. We studied this metabolism in 3-, 12-, and 24-month-old rats. We found an increase in glucose uptake in the control nucleus of 24-month-old rats which was significant when compared to that of 3-month-old rats. We also found a twofold increase in the difference between glucose uptake on the side of nerve transection compared to the control side in old rats.

journal_name

Exp Neurol

journal_title

Experimental neurology

authors

Singer PA,Mehler S

doi

10.1016/0014-4886(90)90012-h

subject

Has Abstract

pub_date

1990-04-01 00:00:00

pages

86-7

issue

1

eissn

0014-4886

issn

1090-2430

pii

0014-4886(90)90012-H

journal_volume

108

pub_type

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