Spatial and temporal distribution of energy.

Abstract:

:Studies of the spatial and temporal distribution of microscopic radiation doses lead to potentially important questions regarding conventional approaches to radiation protection. The short ranges of alpha-particle and Auger-electron emissions from radionuclides lead to uncertainties in assessing their hazards. The conventional extrapolations from intermediate doses to low doses and dose rates are questioned by observed dose-rate effects in the so-called "initial slope," by the total lack of data for single tracks in cells and by the possibility of multiple-cell effects. At all subcellular levels, even down to DNA, high linear-energy-transfer (LET) radiations can produce unique initial damage, different from that possible with low-LET radiations, and therefore may even, in principle, produce unique final biological effects. This questions simple extrapolations from low- to high-LET radiations and the application of universal quality factors to diverse effects. Further understanding of these questions could lead, in future, to substantial increases or decreases in estimations of risk.

journal_name

Health Phys

journal_title

Health physics

authors

Goodhead DT

doi

10.1097/00004032-198808000-00015

subject

Has Abstract

pub_date

1988-08-01 00:00:00

pages

231-40

issue

2

eissn

0017-9078

issn

1538-5159

journal_volume

55

pub_type

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