Radiation hormesis: challenging LNT theory via ecological and evolutionary considerations.

Abstract:

:Ecological and evolutionary considerations suggest that radiation hormesis is made up of two underlying components. The first (a) is background radiation hormesis based upon the background exposure to which all organisms are subjected throughout evolutionary time. The second and much larger component (b) is stress-derived radiation hormesis arising as a protective mechanism derived from metabolic adaptation to environmental stresses throughout evolutionary time especially from climate-based extremes. Since (b) > > (a), hormesis for ionizing radiation becomes an evolutionary expectation at exposures substantially exceeding background. This biological model renders linear no-threshold theory invalid. Accumulating evidence from experimental organisms ranging from protozoa to rodents, and from demographic studies on humans, is consistent with this interpretation. Although hormesis is not universally accepted, the model presented can be subjected to hypothesis-based empirical investigations in a range of organisms. At this stage, however, two consequences follow from this evolutionary model: (1) hormesis does not connote a value judgement usually expressed as a benefit; and (2) there is an emerging and increasingly convincing case for reviewing and relaxing some recommended radiation protection exposure levels in the low range.

journal_name

Health Phys

journal_title

Health physics

authors

Parsons PA

doi

10.1097/00004032-200204000-00011

keywords:

subject

Has Abstract

pub_date

2002-04-01 00:00:00

pages

513-6

issue

4

eissn

0017-9078

issn

1538-5159

journal_volume

82

pub_type

杂志文章
  • Calculation of absorbed energy in the gastrointestinal tract.

    abstract::One goal of this research was to reproduce the photon specific absorbed fraction calculations of Cristy and Eckerman using their gastrointestinal (GI) tract model. A second goal was to calculate photon specific absorbed fraction values for their GI tract model using electron tracking techniques. A final goal was to ca...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199609000-00005

    authors: Poston JW Jr,Kodimer KA,Bolch WE,Poston JW Sr

    更新日期:1996-09-01 00:00:00

  • Cost-benefit of final radiological survey versus radioactive waste disposal.

    abstract::A significant portion of the cost for D&D is related to low-level waste disposal, decontamination, and final radiological survey. For that reason, a careful cost-benefit analysis must be performed weighing the cost of decontaminating and radiologically surveying the building media for release against the cost of dispo...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:

    authors: Barroso J,Roberts S

    更新日期:2003-02-01 00:00:00

  • The delayed pulmonary syndrome following acute high-dose irradiation: a rhesus macaque model.

    abstract::Several radiation dose- and time-dependent tissue sequelae develop following acute high-dose radiation exposure. One of the recognized delayed effects of such exposures is lung injury, characterized by respiratory failure as a result of pneumonitis that may subsequently develop into lung fibrosis. Since this pulmonary...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/HP.0b013e3182a32b3f

    authors: Garofalo M,Bennett A,Farese AM,Harper J,Ward A,Taylor-Howell C,Cui W,Gibbs A,Lasio G,Jackson W 3rd,MacVittie TJ

    更新日期:2014-01-01 00:00:00

  • Tumors and other diseases following childhood x-ray treatment for ringworm of the scalp (Tinea capitis).

    abstract::The objective of the study is to characterize the risk of tumors from radiation exposure to the head and neck. A cohort of 2,224 children given x-ray treatment and 1,380 given only topical medications for ringworm of the scalp (tinea capitis) during 1940-1959 have been followed up for a median of 39 y to determine tum...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-200310000-00003

    authors: Shore RE,Moseson M,Harley N,Pasternack BS

    更新日期:2003-10-01 00:00:00

  • A test of the influence of cyclotron resonance exposures on diatom motility.

    abstract::An attempt was made to test the hypothesis (McLeod et al. 1987; Smith et al. 1987) that a certain combination of direct current and alternating current magnetic field exposures at room temperature results in an increase in motility of a marine diatom (Amphora coffeaeformis) to a maximum value. Diatom motility increase...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199403000-00011

    authors: Prasad AV,Miller MW,Cox C,Carstensen EL,Hoops H,Brayman AA

    更新日期:1994-03-01 00:00:00

  • An investigation of voxel geometries for MCNP-based radiation dose calculations.

    abstract::Voxelized geometry such as those obtained from medical images is increasingly used in Monte Carlo calculations of absorbed doses. One useful application of calculated absorbed dose is the determination of fluence-to-dose conversion factors for different organs. However, confusion still exists about how such a geometry...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/01.HP.0000234039.58356.de

    authors: Zhang J,Bednarz B,Xu XG

    更新日期:2006-11-01 00:00:00

  • Radon-222 levels in New York State homes.

    abstract::Results are presented from a statewide survey that measured annual 222Rn concentrations in over 2000 single-family, owner-occupied homes in New York state. The participants were selected by a random-digit-dialing telephone interview approach developed by Mitofsky-Waksberg which allows inferences to be made from the sa...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199002000-00001

    authors: Perritt RL,Hartwell TD,Sheldon LS,Cox BG,Clayton CA,Jones SM,Smith ML,Rizzuto JE

    更新日期:1990-02-01 00:00:00

  • Foodstuff survey around a major nuclear facility with test of satellite images application.

    abstract::A foodstuff survey was performed around the Savannah River Site, Aiken, South Carolina. It included a census of buildings and fields within 5 km of the boundary and determination of the locations and amounts of crops grown within 80 km of the Savannah River Site center. Recent information for this region was collected...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-200005000-00004

    authors: Twining S,Strydom J,Rosson R,Koffman L,Fledderman P,Kahn B

    更新日期:2000-05-01 00:00:00

  • Assessing the applicability of FISH-based prematurely condensed dicentric chromosome assay in triage biodosimetry.

    abstract::The dicentric chromosome assay (DCA) has been regarded as the gold standard of radiation biodosimetry. The assay, however, requires a 2-d peripheral blood lymphocyte culture before starting metaphase chromosome analyses to estimate biological doses. Other biological assays also have drawbacks with respect to the time ...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/HP.0000000000000182

    authors: Suto Y,Gotoh T,Noda T,Akiyama M,Owaki M,Darroudi F,Hirai M

    更新日期:2015-03-01 00:00:00

  • Estimation of individualized radiation risk from chronic occupational exposure in Russia.

    abstract::Internationally, the upper limit of acceptable individualized risk from occupational exposure for nuclear industry workers is determined by the death probability 10(-3) y(-1). The same risk value of 10(-3) y(-1) is established by the radiation safety standards currently in force in Russia. The United Nations Scientifi...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/01.HP.0000346702.02932.7d

    authors: Ivanov VK,Tsyb AF,Panfilov AP,Agapov AM,Kaidalov OV,Korelo AM,Maksioutov A,Chekin SY,Kashcheyeva PV

    更新日期:2009-08-01 00:00:00

  • The equilibrium factor F.

    abstract::Consideration of the equilibrium factor F between the concentration of the radon daughters and the concentration of radon is a part of the evaluation of the measurements of radon daughter concentrations in dwellings when applying limits. Measurements of radon, radon daughters and air exchange rates have been carried o...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-198308000-00021

    authors: Swedjemark GA

    更新日期:1983-08-01 00:00:00

  • Root absorption of 222Rn and its transfer into above-ground plant organs.

    abstract::Experimental data are given on the content of genetically related pairs of radionuclides (226Ra and 222Rn; 224Ra and 220Rn) in soils and the above-ground phytomass of plants growing on plots with differing genesis of the higher concentrations of natural radionuclides in soils. Methods for determining gaseous radionucl...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-198605000-00002

    authors: Taskayev AI,Popova ON,Alexakhin RM,Testov BV

    更新日期:1986-05-01 00:00:00

  • Environmental distribution and behavior of 3H and 14C around Wolsong Nuclear Power Plants.

    abstract::To estimate of the dispersion trend of 3H and 14C discharged from the Wolsung Nuclear Power Plants, the present level of 3H and 14C in environmental samples in the vicinity of the Wolsong site was studied. Tree-ring cellulose analyses were carried out for retrospective evaluation of 3H and 14C in the environment aroun...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-200006000-00013

    authors: Kim CK,Lee SK,Rho BH,Lee YG

    更新日期:2000-06-01 00:00:00

  • Assessment of the natural radioactivity in the Brazilian state of Rio Grande do Norte.

    abstract::Fifty-one soil samples were collected to a depth of 30 cm in the central and eastern region of the Brazilian state of Rio Grande do Norte. Concentrations of background radionuclides in soil samples were determined by gamma ray spectrometry with an HPGe detector. The average concentrations of 226Ra, 232Th, and 40K in t...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199309000-00008

    authors: Malanca A,Pessina V,Dallara G

    更新日期:1993-09-01 00:00:00

  • Radiocesium contamination at a steel plant in Ireland.

    abstract::Radioactive sources have been inadvertently incorporated into consignments of scrap metal in various locations throughout the world. In 1990, a 3.7 GBq 137 Cs source, due for transfer from a Scottish industrial establishment to one in England, was mistakenly included in a scrap consignment destined for Irish Steel, a ...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199604000-00017

    authors: O'Grady JO,Hone C,Turvey FJ

    更新日期:1996-04-01 00:00:00

  • Lethality due to uranium poisoning is prevented by ethane-1-hydroxy-1,1-biphosphonate (EHBP).

    abstract::The processes of uranium extraction, purification, and manufacture involve the risk of chemical intoxication. Acute uranium poisoning elicits renal failure which in turn may lead to death. Great efforts have been put into the search for a protective agent for acute uranium poisoning. Several chelating agents such as E...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199405000-00005

    authors: Ubios AM,Braun EM,Cabrini RL

    更新日期:1994-05-01 00:00:00

  • Technetium metabolism in goats and swine.

    abstract::The intestinal absorption of 99mTc given as pertechnetate (TcO4-) was studied in female goats and swine. In goats given TcO4- orally, only a small fraction of the given radioactivity was found in milk (x = 0.1% of dose) and urine (x = 1.2% of dose). These figures were not substantially changed by pre-treatment with I....

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-198908000-00012

    authors: Jones BE

    更新日期:1989-08-01 00:00:00

  • Radiation dosimetry of a graphite moderated radium-beryllium source.

    abstract::The Brookhaven National Laboratory Sigma Pile is a radium-beryllium neutron source imbedded in a cube of graphite blocks. The pile is approximately 2.13 m on four sides and is 3.07 m high. Thermoluminescent dosimeters were used to determine the neutron and gamma-ray dose rates in the pile. Gamma-ray dose rate measurem...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:

    authors: Holden NE,Reciniello RN,Hu JP

    更新日期:2004-05-01 00:00:00

  • Towards a generalized model for the primary and secondary contamination of lakes by Chernobyl-derived radiocesium.

    abstract::As part of the UK Ministry of Agriculture Fisheries and Food Directorate of Fisheries Research (MAFF/DFR) post-Chernobyl monitoring program, a detailed study was carried out of the change over time in dissolved-phase 137Cs concentrations in a number of lakes in Cumbria, UK. These measurements have been combined with p...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199706000-00007

    authors: Smith JT,Leonard DR,Hilton J,Appleby PG

    更新日期:1997-06-01 00:00:00

  • Distribution of natural radioactivity in rocks from Ikogosi-Ekiti, Southwestern Nigeria and its radiological implications.

    abstract::The natural radioactivity in some rock samples in Ikogosi-Ekiti, Southwestern Nigeria, has been measured using a very sensitive gamma spectroscopic system consisting of a 76 mm x 76 mm NaI(TI) scintillation detector system coupled to a versatile Canberra Series 10 plus multichannel analyzer. The average concentrations...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-200008000-00013

    authors: Ajayi OS

    更新日期:2000-08-01 00:00:00

  • Diurnal and seasonal variations of radon levels, effects of climatic conditions, and radon exposure assessment in a former uranium metal production facility.

    abstract::Storage of radon-producing material in two silos and two waste pits is one of the major environmental and occupational issues at a former uranium production facility, now a Superfund site. In addition, up to 100 metric tons of thorium is stored on the northeast side of the site. Concentrations of radium up to 17,600 B...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-199805000-00004

    authors: Merrill EA,Akbar-Khanzadeh F

    更新日期:1998-05-01 00:00:00

  • Evaluation of scattered radiation in a calibration range using exposure rate energy spectra.

    abstract::ISO standard 4037 specifies that for calibrating protection level dosimeters, scattered radiation should contribute less than 5% of the exposure. In previous work, the authors reported the results of an MCNP analysis of the shadow shield technique that was performed for a calibration range with a Cs irradiator. This p...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/HP.0b013e3182259a98

    authors: Petrie CM,Blue TE,Herminghuysen K

    更新日期:2012-01-01 00:00:00

  • Health physics challenges involved with opening a "seventeen-inch" concrete waste vault.

    abstract::This paper describes the various activities involved with opening a sealed legacy "Seventeen-inch" concrete vault and the health physics challenges and solutions employed. As part of a legacy waste stream that was removed from the former Hazardous Waste Management Facility at Brookhaven National Laboratory, the "Seven...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/01.hp.0000156059.17528.56

    authors: Sullivan PT,Pizzulli M

    更新日期:2005-05-01 00:00:00

  • Measuring Workload with Paired Detectors.

    abstract::Linear accelerator workloads for each available photon energy are important quantities to know for radiation safety considerations, and presented is a technique to measure the workload using paired detectors. The signals from the two detectors can give sufficient information to separate the signal contributions from 6...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/HP.0000000000000984

    authors: Corns R,Schroeder C,Sandhu G,Henderson K,McKay I

    更新日期:2019-09-01 00:00:00

  • Does tributyl phosphate influence the radiation risk of a highly proliferating system--the early mouse embryo in vitro?

    abstract::Two-cell mouse embryos were exposed in vitro to tributyl phosphate, x rays, or a combination of both. In-vitro development of the embryos was followed microscopically (cleavage to four- and eight-cell embryos, formation of morulae and blastocysts, and hatching of blastocysts). Effects on proliferation were estimated b...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-198712000-00009

    authors: Müller WU,Streffer C,Markoski L

    更新日期:1987-12-01 00:00:00

  • Sorption of tin on human teeth.

    abstract::The sorption of tin ions on human teeth from water and other drinks has been studied by the radioactive tracer technique using the isotope 113Sn (T(1/2) = 115.1 d) as a tracer. The tooth holds a minimum amount of tin from coffee and a maximum amount is held from water and from tea with sugar. The same technique was al...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-200201000-00014

    authors: Helal AA,Alian GA,Madbouly HA

    更新日期:2002-01-01 00:00:00

  • Systemic burden and body burden of Pu in man: comparison of results from bioassay and autopsy.

    abstract::A case of plutonium deposition in man within the range of 190 Bq by inhalation from about 12 yr ago is reported. An estimate of systemic burden was made based on analyses of urine and faeces and the models of Langham, Beach/Dolphin, and Durbin while the individual was alive. This estimate was compared with autopsy fin...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-198404000-00008

    authors: Ohlenschlaeger L,Schieferdecker H,Schmidt-Martin W

    更新日期:1984-04-01 00:00:00

  • Radiological findings of accidental radiation injury of the fingers: a case report.

    abstract::This case report describes the medical follow-up of a 46-y-old (at the time of exposure) man who in 1971 accidentally exposed the fingers of his right hand to gamma-ray radiation from an iridium source that was used for nondestructive testing [estimated radiation dose: 26 Gy to 90 Gy (2,600 rad to 9,000 rad)]. No prom...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-200101000-00012

    authors: Nakagawa K,Kozuka T,Akahane M,Suzuki G,Akashi M,Hosoi Y,Aoki Y,Ohtomo K

    更新日期:2001-01-01 00:00:00

  • Non-invasive measurement of water content in lung phantom by neutrons: latest improvements to the technique.

    abstract::The novel technique for measuring the water content in lungs based on the slowing down of fast neutrons has been improved making possible its clinical use on patients. This goal has been reached by performing computer simulations that closely mimic the experimental setup and by acquiring a new set of measurements obta...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/00004032-200112000-00022

    authors: Campi F,Dionigi F

    更新日期:2001-12-01 00:00:00

  • Reevaluation of (241)Am content in the USTUR case 0102 leg phantom.

    abstract::The (241)Am contents in the United States Transuranium and Uranium Registries' (USTUR) case 0102 leg phantom were previously estimated to be 1,243 ± 11 Bq. Recent analysis of the computed tomography images of the phantom revealed multiple bone structures missing from various regions of the phantom skeleton including: ...

    journal_title:Health physics

    pub_type: 杂志文章

    doi:10.1097/hp.0b013e318269bf81

    authors: Tabatadze G,Brey RR,Kramer GH,Capello K,Meldrum DJ

    更新日期:2013-01-01 00:00:00