A set of composite, non-redundant EEG measures of NREM sleep based on the power law scaling of the Fourier spectrum.

abstract：:RNA interference (RNAi) is a robust tool to study gene functions as well as potential for insect pest control. Finding suitable target genes is the key step in the development of an efficient RNAi-mediated pest control technique. Based on the transcriptome of Chilo suppressalis, 24 unigenes which putatively associated...

journal_title：Scientific reports

authors： Zhu J,Dong YC,Li P,Niu CY

更新日期：2016-06-29 00:00:00

abstract：:IHC4 and PAM50 assays have been shown to provide additional prognostic information for patients with early breast cancer. We evaluated whether incorporating TP53 mutation analysis can further enhance their prognostic accuracy. We examined TP53 mutation and the IHC4 score in tumors of 605 patients diagnosed with stage ...

journal_title：Scientific reports

authors： Lin CH,Chen IC,Huang CS,Hu FC,Kuo WH,Kuo KT,Wang CC,Wu PF,Chang DY,Wang MY,Chang CH,Chen WW,Lu YS,Cheng AL

更新日期：2015-12-16 00:00:00

abstract：:Perception can often be described as a statistically optimal inference process whereby noisy and incomplete sensory evidence is combined with prior knowledge about natural scene statistics. Previous evidence has shown that humans tend to underestimate the speed of unreliable moving visual stimuli. This finding has bee...

journal_title：Scientific reports

authors： Senna I,Parise CV,Ernst MO

更新日期：2015-09-15 00:00:00

abstract：:Semi-arid ecosystems are key contributors to the global carbon cycle and may even dominate the inter-annual variability (IAV) and trends of the land carbon sink, driven largely by the El Niño-Southern Oscillation (ENSO). The linkages between dynamics of semi-arid ecosystems and climate at the hemispheric scale however...

journal_title：Scientific reports

authors： Zhang A,Jia G,Epstein HE,Xia J

更新日期：2017-02-09 00:00:00

abstract：:The molecular chaperone Hsc70 performs essential tasks by folding proteins. Hsc70 is driven by the hydrolysis of ATP and tuned by the association with various co-chaperones. One such cofactor is the nematode nucleotide exchange factor UNC-23, whose mutation disrupts muscle attachment and induces a severe head-bent phe...

journal_title：Scientific reports

authors： Papsdorf K,Sima S,Schmauder L,Peter S,Renner L,Hoffelner P,Richter K

更新日期：2019-08-16 00:00:00

abstract：:We have recently reported that Kupffer cells consist of two subsets, radio-resistant resident CD68+ Kupffer cells and radio-sensitive recruited CD11b+ Kupffer cells/macrophages (Mφs). Non-alcoholic steatohepatitis (NASH) is characterized not only by hepatic steatosis but also chronic inflammation and fibrosis. In the ...

journal_title：Scientific reports

authors： Nakashima H,Nakashima M,Kinoshita M,Ikarashi M,Miyazaki H,Hanaka H,Imaki J,Seki S

更新日期：2016-10-06 00:00:00

abstract：:OVGP1 is the major non-serum glycoprotein in the oviduct fluid at the time of fertilization and early embryo development. Its activity differs among species. Here, we show that the C-terminal region of recombinant OVGP1 regulates its binding to the extracellular zona pellucida and affects its activity during fertiliza...

journal_title：Scientific reports

authors： Algarra B,Han L,Soriano-Úbeda C,Avilés M,Coy P,Jovine L,Jiménez-Movilla M

更新日期：2016-09-07 00:00:00

abstract：:Dengue fever is one of the most important mosquito-borne viral infections in large parts of tropical and subtropical countries and is a significant public health concern and socioeconomic burden. There is an urgent need to develop antivirals that can effectively reduce dengue virus (DENV) replication and decrease vira...

journal_title：Scientific reports

authors： Jung E,Nam S,Oh H,Jun S,Ro HJ,Kim B,Kim M,Go YY

更新日期：2019-06-18 00:00:00

abstract：:Photocatalysis is a promising strategy to address the global environmental and energy challenges. However, the studies on the application of the photocatalytically degraded dye-polluted water and the multi-purpose use of one type of catalyst have remained sparse. In this report, we try to demonstrate a concept of mult...

journal_title：Scientific reports

authors： Zhang Q,Zhang Y,Meng Z,Tong W,Yu X,An Q

更新日期：2017-09-25 00:00:00

abstract：:Ca2+ release-activated Ca2+ (CRAC) channels elevate cytoplasmic Ca2+ concentration, which is essential for T cell activation, differentiation and effector functions. T cell receptor stimulation induces depletion of the endoplasmic reticulum (ER) Ca2+ stores, which is sensed by stromal interaction molecule 1 (STIM1). S...

journal_title：Scientific reports

authors： Woo JS,Sun Z,Srikanth S,Gwack Y

更新日期：2020-09-02 00:00:00

abstract：:Low-dimensional semiconductor structurers formed on a substrate surface at pre-defined locations and with nano-precision placement is of vital interest. The potential of tailoring their electrical and optical properties will revolutionize the next generation of optoelectronic devices. Traditionally, highly aligned sel...

journal_title：Scientific reports

authors： Dushaq G,Rasras M

更新日期：2019-10-02 00:00:00

abstract：:Recent experimental work in the field of synthetic protocell biology has shown that prebiotic vesicles are able to 'steal' lipids from each other. This phenomenon is driven purely by asymmetries in the physical state or composition of the vesicle membranes, and, when lipid resource is limited, translates directly into...

journal_title：Scientific reports

authors： Shirt-Ediss B,Ruiz-Mirazo K,Mavelli F,Solé RV

更新日期：2014-07-14 00:00:00

abstract：:Poly(N-isopropylacrylamide) (PNIPAm) is widely used to fabricate cell sheet surfaces for cell culturing, however copolymer and interpenetrated polymer networks based on PNIPAm have been rarely explored in the context of tissue engineering. Many complex and expensive techniques have been employed to produce PNIPAm-base...

journal_title：Scientific reports

authors： Sanzari I,Buratti E,Huang R,Tusan CG,Dinelli F,Evans ND,Prodromakis T,Bertoldo M

更新日期：2020-04-09 00:00:00

abstract：:A novel type of sub-lattice of the Jahn-Teller (JT) centers was arranged in Ti-doped barium hexaferrite BaFe12O19. In the un-doped crystal all iron ions, sitting in five different crystallographic positions, are Fe3+ in the high-spin configuration (S = 5/2) and have a non-degenerate ground state. We show that the elec...

journal_title：Scientific reports

authors： Gudkov VV,Sarychev MN,Zherlitsyn S,Zhevstovskikh IV,Averkiev NS,Vinnik DA,Gudkova SA,Niewa R,Dressel M,Alyabyeva LN,Gorshunov BP,Bersuker IB

更新日期：2020-04-27 00:00:00

abstract：:It is well known that tumour-associated macrophages (TAMs) play an important role in tumour development by modulating the tumour microenvironment, and targeting of protumour activation or the M2 polarization of TAMs is expected to be an effective therapy for cancer patients. We previously demonstrated that onionin A (...

journal_title：Scientific reports

authors： Tsuboki J,Fujiwara Y,Horlad H,Shiraishi D,Nohara T,Tayama S,Motohara T,Saito Y,Ikeda T,Takaishi K,Tashiro H,Yonemoto Y,Katabuchi H,Takeya M,Komohara Y

更新日期：2016-07-12 00:00:00

abstract：:Rho GTPases are master regulators of the eukaryotic cytoskeleton. The activation of Rho GTPases is governed by Rho guanine nucleotide exchange factors (GEFs). Three RhoGEF isoforms are produced by the gene ARHGEF25; p63RhoGEF580, GEFT and a recently discovered longer isoform of 619 amino acids (p63RhoGEF619). The subc...

journal_title：Scientific reports

authors： van Unen J,Yin T,Wu YI,Mastop M,Gadella TW Jr,Goedhart J

更新日期：2016-11-11 00:00:00

abstract：:Mitochondrial activity is central to tissue homeostasis. Mitochondria dysfunction constitutes a hallmark of many genetic diseases and plays a key role in tumor progression. The essential role of mitochondria, added to their recently documented capacity to transfer from cell to cell, obviously contributes to their curr...

journal_title：Scientific reports

authors： Caicedo A,Fritz V,Brondello JM,Ayala M,Dennemont I,Abdellaoui N,de Fraipont F,Moisan A,Prouteau CA,Boukhaddaoui H,Jorgensen C,Vignais ML

更新日期：2015-03-13 00:00:00

abstract：:Media reports of a celebrity's suicide may be followed by copycat suicides, and the impact may vary in different age and sex subgroups. We proposed a quantitative framework to assess the vulnerability of age and sex subgroups to copycat suicide and used this method to investigate copycat suicides in relation to the su...

journal_title：Scientific reports

authors： Yi H,Hwang J,Bae HJ,Kim N

更新日期：2019-11-21 00:00:00

abstract：:L-Asparaginase (L-asparagine aminohydrolase, E.C. 3.5.1.1) has been proven to be competent in treating Acute Lymphoblastic Leukaemia (ALL), which is widely observed in paediatric and adult groups. Currently, clinical L-Asparaginase formulations are derived from bacterial sources such as Escherichia coli and Erwinia ch...

journal_title：Scientific reports

authors： Ashok A,Doriya K,Rao JV,Qureshi A,Tiwari AK,Kumar DS

更新日期：2019-02-05 00:00:00

abstract：:Amiodarone accumulates in the liver, where it increases x-ray attenuation due to its iodine content. We evaluated liver attenuation in patients treated and not treated with amiodarone using true-non-contrast (TNC) and virtual-non-contrast (VNC) images acquired with spectral-detector-CT (SDCT). 142 patients, of which 2...

journal_title：Scientific reports

authors： Laukamp KR,Lennartz S,Hashmi A,Obmann M,Ho V,Große Hokamp N,Graner FP,Gilkeson R,Persigehl T,Gupta A,Ramaiya N

更新日期：2020-04-24 00:00:00

abstract：:Lower corrected calcium (cCa) levels are associated with a better prognosis among incident dialysis patients. However, cCa frequently overestimates ionized calcium (iCa) levels. The prognostic importance of the true calcium status defined by iCa remains to be revealed. We conducted a retrospective cohort study of inci...

journal_title：Scientific reports

authors： Yamaguchi S,Hamano T,Doi Y,Oka T,Kajimoto S,Kubota K,Yasuda S,Shimada K,Matsumoto A,Hashimoto N,Sakaguchi Y,Matsui I,Isaka Y

更新日期：2020-03-10 00:00:00

abstract：:One of the health hazards of PM2.5 exposure is to induce pulmonary inflammatory responses. In our previous study, we demonstrated that exposing both the immortalized and primary human bronchial epithelial cells to PM2.5 results in a significant upregulation of VEGF production, a typical signaling event to trigger chro...

journal_title：Scientific reports

authors： Xu H,Xu X,Wang H,Qimuge A,Liu S,Chen Y,Zhang C,Hu M,Song L

更新日期：2019-11-12 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Nagy ÁG,Kámán J,Horváth R,Bonyár A

更新日期：2019-11-26 00:00:00

abstract：:Repeated cycles of post-remission high-dose cytarabine (Ara-C) have been suggested to improve survival in core binding factor (CBF) acute myeloid leukaemia (AML). High-dose Ara-C used for induction regimens has also been reported to be associated with increased treatment-related mortality (TRM). Few data are available...

journal_title：Scientific reports

authors： Wang B,Zhang J,Hua X,Li H,Wang Z,Yang B

更新日期：2020-01-20 00:00:00

abstract：:Mutations at positions 70 and/or 91 in the core protein of genotype-1b, hepatitis C virus (HCV) are associated with hepatocellular carcinoma (HCC) risk in Asian patients. To evaluate this in a US population, the relationship between the percentage of 70 and/or 91 mutant HCV quasispecies in baseline serum samples of ch...

journal_title：Scientific reports

authors： El-Shamy A,Pendleton M,Eng FJ,Doyle EH,Bashir A,Branch AD

更新日期：2016-06-01 00:00:00

abstract：:As the global prevalence of childhood obesity continues to rise, researchers and clinicians have sought to develop more effective and personalized intervention techniques. In doing so, obesity interventions have expanded beyond the traditional context of nutrition to address several facets of a child's life, including...

journal_title：Scientific reports

authors： Feldman K,Solymos GMB,de Albuquerque MP,Chawla NV

更新日期：2019-12-11 00:00:00

abstract：:The existing molecular cloning methods are often limited by the availability of suitable restriction sites. It is still a challenge for simultaneous cloning of multiple fragments into different sites of a single vector. Here we developed a novel method named improved overlap extension PCR (IOEP) for restriction enzyme...

journal_title：Scientific reports

authors： Guo W,Xie B,Jiang M,Zhu XJ,Qiu M,Dai ZM

更新日期：2019-10-30 00:00:00

abstract：:Zinc oxy-selenide Zn(O,Se) is a novel material, that can replace the toxic CdS buffer layer in thin film solar cells and other optoelectronic devices. In this paper a systematic study of the structural, optical and electrical properties of Zn(O,Se) layers, grown by pulsed laser deposition under 50 mTorr of nitrogen ba...

journal_title：Scientific reports

authors： Abdalla A,Bereznev S,Spalatu N,Volobujeva O,Sleptsuk N,Danilson M

更新日期：2019-11-25 00:00:00

abstract：:Detection of sedimentary cycles is difficult in fine-grained or homogenous sediments but is a prerequisite for the interpretation of depositional environments. Here we use a new autocorrelation analysis to detect cycles in a homogenous sediment core, E602, from the northern shelf of the South China Sea. Autocorrelatio...

journal_title：Scientific reports

authors： Xiao S,Li R,Chen M

更新日期：2013-01-01 00:00:00

abstract：:The movement protein VP37 of broad bean wilt virus 2 (BBWV 2) forms tubules in the plasmodesmata (PD) for the transport of virions between cells. This paper reports a mutual association between the BBWV 2 VP37-tubule complex and PD at the cytological level as determined by transmission electron microscopy. The generat...

journal_title：Scientific reports

authors： Xie L,Shang W,Liu C,Zhang Q,Sunter G,Hong J,Zhou X

更新日期：2016-02-23 00:00:00