Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Nagy ÁG,Kámán J,Horváth R,Bonyár Adoi
10.1038/s41598-019-54634-9subject
Has Abstractpub_date
2019-11-26 00:00:00pages
18009issue
1issn
2045-2322pii
10.1038/s41598-019-54634-9journal_volume
9pub_type
已发布勘误abstract::Organic matter production and decomposition primarily modulate the atmospheric O2 and CO2 levels. The long term marine primary productivity is controlled by the terrestrial input of phosphorus (P), while the marine P cycle would also affect organic matter production. In the past 540 million years, the evolution of ter...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62816-z
更新日期:2020-04-02 00:00:00
abstract::Irreversible electroporation (IRE) as a non-thermal tumor ablation technology has been studied for the treatment of pancreatic carcinoma and has shown a significant survival benefit. We discovered that moderate heating (MH) at 43 °C for 1-2 minutes significantly enhanced ex vivo IRE tumor ablation of Pan02 cells by 5....
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12227-4
更新日期:2017-09-18 00:00:00
abstract::Cell lytic enzymes represent an alternative to chemical decontamination or use of antibiotics to kill pathogenic bacteria, such as listeria. A number of phage cell lytic enzymes against listeria have been isolated and possess listericidal activity; however, there has been no attempt to incorporate these enzymes onto s...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep01584
更新日期:2013-01-01 00:00:00
abstract::We found that the coagulation and cytokine pathways were important mechanisms involve in the degeneration of intervertebral discs (IVD) using a microarray approach to analyze gene expression in different grades of specimens. Furthermore, using a cytokine/chemokine array, a significant increase in CXCL8 expression was ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09122-3
更新日期:2017-08-17 00:00:00
abstract::In this study, to fabricate stable floating photocatalytic spheres, facile alcohol solvothermal reduction was first employed to modify commercial TiO2 (P25) photocatalysts to harvest visible light and improve their performances for photodegrading phenol in seawater exciting by visible light. Floating photocatalytic sp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-50457-w
更新日期:2019-09-25 00:00:00
abstract::The domain wall-related change in the anisotropic magnetoresistance in L-shaped permalloy nanowires is measured as a function of the magnitude and orientation of the applied magnetic field. The magnetoresistance curves, compiled into so-called domain wall magnetoresistance state space maps, are used to identify highly...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep06045
更新日期:2014-08-13 00:00:00
abstract::Modulation of initial burst and long term release from electrospun fibrous mats can be achieved by sandwiching the drug loaded mats between hydrophobic layers of fibrous polycaprolactone (PCL). Ibuprofen (IBU) loaded PCL fibrous mats (12% PCL-IBU) were sandwiched between fibrous polycaprolactone layers during the proc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-74885-1
更新日期:2020-10-23 00:00:00
abstract::During development, cell division often generates two daughters with different developmental fates. Distinct daughter identities can result from the physical polarity and size asymmetry itself, as well as the subsequent activation of distinct fate programmes in each daughter. Asymmetric divisions are a feature of the ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-01675-7
更新日期:2017-06-14 00:00:00
abstract::Heart failure with preserved ejection fraction (HFpEF) affects more women than men, suggesting gender to play a major role in disease evolution. However, studies investigating gender differences in HFpEF are limited. In the present study we aimed to describe gender differences in a well-characterized HFpEF cohort. Con...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-19507-7
更新日期:2018-01-18 00:00:00
abstract::Efforts for tissue engineering vascular grafts focuses on the tunica media and intima, although the tunica adventitia serves as the primary structural support for blood vessels. In surgery, during endarterectomies, surgeons can strip the vessel, leaving the adventitia as the main strength layer to close the vessel. He...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21681-7
更新日期:2018-02-19 00:00:00
abstract::Generating various laser sources is important in the communication systems. We propose an approach that uses a mechanical resonator coupled with the optical fibre system to produce periodic and chaotic optical signals. The resonator is structured in such a way that the nonlinear oscillation occurs conveniently. The me...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05020-w
更新日期:2017-07-06 00:00:00
abstract::New strategies are needed to develop better tools to control TB, including identification of novel antigens for vaccination. Such Mtb antigens must be expressed during Mtb infection in the major target organ, the lung, and must be capable of eliciting human immune responses. Using genome-wide transcriptomics of Mtb in...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37793
更新日期:2016-11-28 00:00:00
abstract::A sensitive and selective chemiluminescence (CL) sensor based on the peroxidase-like activity of copper nanoclusters was established for the detection of cholesterol. Copper nanoclusters catalyse the CL reaction between luminol and H2O2. Because H2O2 is the oxidative product of cholesterol in the presence of cholester...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39157
更新日期:2016-12-14 00:00:00
abstract::Controlling light and heat via metamaterials has presented interesting technological applications using transformation optics (TO) and transformation thermodynamics (TT). However, such devices are commonly mono-physics and mono-purpose, because the used metamaterial is designed to deal with one type of physical mechan...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-29866-w
更新日期:2018-07-30 00:00:00
abstract::Most pancreatic cancer (PC) patients manifest multiple liver metastases at the time of diagnosis. Activated platelets play a key role in tumor growth and tumor metastases. Mean platelet volume (MPV) is a platelet index and is altered in patients with malignancies. This study aimed to evaluate whether MPV can effective...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-24539-0
更新日期:2018-04-16 00:00:00
abstract::Although the power conversion efficiency (PCE) of perovskite solar cells (PSCs) reached up to 23%, their short lifetime and fast degradation still remain as the main challenges. In this work, a new facile optical method based on the high power UV-irradiation is presented for the recovery of the degraded PSCs. Addition...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-45756-1
更新日期:2019-07-01 00:00:00
abstract::Adolescence is a critical period for the development of higher-order cognitive functions. Unlike in humans, very limited tools are available to assess such cognitive abilities in adolescent rodents. We implemented a modified 5-Choice Serial Reaction Time Task (5CSRTT) to selectively measure attentiveness, impulsivity,...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10112-8
更新日期:2017-08-30 00:00:00
abstract::Methadone maintenance treatment (MMT) can induce impairments in brain function and structure, despite its clinical effectiveness. However, the effect of chronic MMT on brain white matter (WM) is not fully known. Thirty-three MMT patients underwent diffusion tensor imaging (DTI) twice - at the start of the study (Scan1...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep19662
更新日期:2016-01-22 00:00:00
abstract::Bringing oxygen atoms from infinite, passing equilibrium until short enough distances, we aim to reveal the 4f5d electron bonding property and its relevance to the peculiar physical properties within PrO2 based on both accounting for electron Coulomb repulsion and spin-orbit coupling effects in combination with Wannie...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-34336-4
更新日期:2018-10-30 00:00:00
abstract::Inhibitors of PD-1 signaling have revolutionized cancer therapy. PD-1 and PD-L1 antibodies have been approved for the treatment of cancer. To date, therapeutic PD-1 inhibitors have not been compared in a functional assay. We used an efficient T cell reporter platform to evaluate the efficacy of five clinically used PD...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-47910-1
更新日期:2019-08-07 00:00:00
abstract::RNA protein interactions (RPI) play a pivotal role in the regulation of various biological processes. Experimental validation of RPI has been time-consuming, paving the way for computational prediction methods. The major limiting factor of these methods has been the accuracy and confidence of the predictions, and our ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-27814-2
更新日期:2018-06-22 00:00:00
abstract::Honeybees (Apis mellifera L.), which unquestionably play an economically important role in pollination and agricultural production, are at risk of decline. To study changes in gene expression in insects upon exposure to pesticides or other external stimuli, appropriate reference genes are required for data normalizati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73125-w
更新日期:2020-09-30 00:00:00
abstract::Walnuts (Juglans spp.) are economically important nut and timber species with a worldwide distribution. Using the published Persian walnut genome as a reference for the assembly of short reads from six Juglans species and several interspecific hybrids, we identified simple sequence repeats in 12 Juglans nuclear and or...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39793-z
更新日期:2019-03-06 00:00:00
abstract::Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis (Bt) are spore-forming members of the Bacillus cereus group. Spores of B. cereus group species are encircled by exosporium, which is composed of an external hair-like nap and a paracrystalline basal layer. Despite the extensive studies on the structure of...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep19005
更新日期:2016-01-25 00:00:00
abstract::Epigenetic deregulation, such as the reduction of histone acetylation levels, is thought to be causally linked to various maladies associated with aging. Consequently, histone deacetylase inhibitors are suggested to serve as epigenetic therapy by increasing histone acetylation. However, previous work suggests that man...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-22674-2
更新日期:2018-03-08 00:00:00
abstract::Amniotic membrane (AM) has been widely used as a temporary or permanent graft in the treatment of various ocular surface diseases. In this study, we compared the epithelial wound healing and tissue remodeling after ocular surface reconstruction with intact amniotic membrane (iAM) or denuded amniotic membrane (dAM). Pa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-24694-4
更新日期:2018-04-23 00:00:00
abstract::Kmmig1 as a disrupted mutant of MIG1 encoding a regulator for glucose repression in Kluyveromyces marxianus exhibits a histidine-auxotrophic phenotype. Genome-wide expression analysis revealed that only HIS4 in seven HIS genes for histidine biosynthesis was down-regulated in Kmmig1. Consistently, introduction of HIS4 ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46411-5
更新日期:2019-07-09 00:00:00
abstract::Dysregulation of the ubiquitin proteasome system (UPS) has been linked to schizophrenia but it is not clear if this dysregulation is detectable in both brain and blood. We examined free mono-ubiquitin, ubiquitinated proteins, catalytic ubiquitination, and proteasome activities in frozen postmortem OFC tissue from 76 (...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-38490-1
更新日期:2019-02-19 00:00:00
abstract::The role of transforming growth factor-β (TGF-β) signaling in cancer progression is still under debate. To determine the function of TGF-β signaling in bladder cancer progression, we conditionally knocked out the Tgfbr2 in mouse model after a N-butyl-N-4-hydroxybutyl Nitrosamine induced bladder carcinogenesis. We foun...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29479
更新日期:2016-07-05 00:00:00
abstract::Plastic pollution is a rapidly worsening environmental problem, especially in oceanic habitats. Environmental pollution with microplastic particles is also causing food consumed by humans to be increasingly polluted, including table salts. Therefore, we present the first study which focuses only on table salt products...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46417-z
更新日期:2019-07-12 00:00:00