Abstract：
:Although they account for a small proportion of burns in paediatrics, injuries from chemicals can be just as devastating as other mechanisms of burn injury. At least 25,000 chemicals exist which can cause burns: in children, they are often caused by household chemicals via accidental exposure. The mechanism by which corrosive substances produce chemical burns highlights the importance of early and plentiful irrigation of the burn area, removal of contaminated clothes and careful clinical assessment. Surgical intervention is uncommon but often follows the principles for thermal burns. This article reviews the aetiology, incidence, clinical presentation, management, complications and prevention of chemical burns. What is Known • Chemical burns in paediatrics are often caused by accidental exposure to chemicals available at home • Differences in the pathophysiology of chemical burns reinforces the need for early irrigation What is New • New irrigation fluids show promise in adults and need further study in children • The nature of chemical cutaneous burns can make assessment of wound depth difficult. Laser Doppler Imaging (LDI) is an accurate technique that can be used clinically to determine burn depth in thermal burns and is an area of future interest in the assessment of chemical burns.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Nguyen ATM,Chamberlain K,Holland AJAdoi
10.1007/s00431-020-03905-zsubject
Has Abstractpub_date
2021-01-06 00:00:00eissn
0340-6199issn
1432-1076pii
10.1007/s00431-020-03905-zpub_type
杂志文章,评审abstract：:The primary objective of this study was to evaluate whether pediatric respiratory rate-oxygenation index (p-ROXI) and variation in p-ROXI (p-ROXV) can serve as objective markers in children with high-flow nasal cannula (HFNC) failure. In this prospective, single-center observational study, all patients who received HF...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-020-03847-6
更新日期：2020-10-19 00:00:00
abstract：:Human metapneumovirus (hMPV) is a recently discovered pathogen in respiratory tract infection. The published literature suggests milder illness severity in hMPV compared with respiratory syncytial virus (RSV) infection. In two consecutive seasons, 637 nasopharyngeal aspirates from pediatric patients were tested by hMP...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-006-0105-4
更新日期：2006-07-01 00:00:00
abstract：:The main goal for the neonatologist is to facilitate the adaptation to extra-uterine life during initial transition, while minimizing lung injury opening and protecting the premature lung from the first breath onwards. An appropriate management from birth should lead to the achievement of an early functional residual ...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-017-2984-y
更新日期：2017-10-01 00:00:00
abstract：:A benign cystic nephroblastoma in a 6-month-old boy is presented. Erroneous interpretation as malignant nephroblastoma led to unnecessarily aggressive therapy. There is no evidence of recurrence or metastatic disease 12 years after the initial resection. As shown in our case and in the others previously reported in th...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00447474
更新日期：1979-05-18 00:00:00
abstract：:Premature newborns are particularly vulnerable to iatrogenic hypothyroidism due to iodine exposure, usually through skin absorption of iodine-containing disinfectants or intravenous administration of iodinated contrast agents. We report here a case of severe iatrogenic hypothyroidism with goiter and cholestasis, disco...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-008-0782-2
更新日期：2009-04-01 00:00:00
abstract：:The use of supra-physiological, exogenous corticosteroids in pregnancy may lead to neonatal adrenal suppression. We report on a single-center, case series study carried out between 2006 and 2014, which included all newborns (n = 16) of mothers using prednisolone ≥10 mg/day during pregnancy. Newborns were routinely ass...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-017-2949-1
更新日期：2017-08-01 00:00:00
abstract：UNLABELLED:We report fives sporadic cases of hyperekplexia or startle disease characterized by a highly exaggerated startle reflex and tonic attacks. Affected neonates suffer from prolonged periods of stiffness and are at risk for sudden death from apnea. An early diagnosis is needed. Sudden loud sounds, unexpected tac...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-005-0015-x
更新日期：2006-02-01 00:00:00
abstract：:Six patients are described with a combination of early onset of neurological symptoms, gross cerebral changes and elevated concentrations of pyruvate and lactate in cerebrospinal fluid. Although at least five of the six patients appear to have a generalised defect in pyruvate metabolism, reflected in deficient pyruvat...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00442603
更新日期：1988-01-01 00:00:00
abstract：UNLABELLED:To study the developmental effects of prenatal exposure to opiates, a prospective follow up study of 34 drug-exposed (opiates and nicotine) and 42 reference infants (nicotine exposure only) was conducted from January 1992 to September 1995. At the time of delivery, 12 of 34 mothers used opiates without medic...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310050923
更新日期：1998-09-01 00:00:00
abstract：UNLABELLED:Increased breastfeeding was suggested as a contributing factor to significant hyperbilirubinemia. The aim of this study was to identify the risk factors associated with jaundice in exclusively breastfed term neonates. We retrospectively reviewed all consecutively live-born neonates from August 2009 to July 2...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-011-1512-8
更新日期：2012-01-01 00:00:00
abstract：:We studied the clinical features, laboratory and thyroid functions and thyrotropin (TSH)-receptor and thyroid-stimulation antibodies in 21 patients with atrophic auto-immune thyroiditis (AAT) and 48 patients with goitrous auto-immune thyroiditis (GAT) of childhood onset. The clinical features of patient with AAT were ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01957685
更新日期：1990-05-01 00:00:00
abstract：BACKGROUND:Calcaneal apophysitis, or Sever's disease, is a traction apophysitis. It is a frequent cause of heel pain in children. Knowledge about the exact incidence of calcaneal apophysitis in the general population, however, is lacking. DESIGN:Cross-sectional study. METHODS:From 34 general practices, records of pat...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-013-2219-9
更新日期：2014-05-01 00:00:00
abstract：:A girl, 13 months of age, presented with generalised granulomatous skin, hair and mucosal candidiasis. Her lymphocytes failed to respond in vitro to Candida antigen (CA); the intradermal test with CA was also negative. Serum immunoglobulins, complement components, granulocyte functions (phagocytic and fungicidal), T-c...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00442747
更新日期：1984-11-01 00:00:00
abstract：:Biochemical markers such as plasma and urinary metabolite concentrations and in vitro enzyme activity are of limited prognostic value in the most common disorders of propionate metabolism, methylmalonic acidaemia (MMA) and propionic acidaemia (PA). In vivo propionate oxidation was compared with conventional prognostic...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02009661
更新日期：1990-03-01 00:00:00
abstract：UNLABELLED:This prospective clinical case-control study describes the effect of an inpatient multicomponent treatment programme for obese children and adolescents on their weight and psychological well being. We studied 38 patients and 38 controls on the waiting list, matched for age and gender, referred because of obe...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-003-1155-5
更新日期：2003-06-01 00:00:00
abstract：:Blunt cardiac injury may occur in patients after suffering nonpenetrating trauma of the chest. It encompasses a wide spectrum of cardiac injury with varied severity and clinical presentation. Electrocardiographic abnormalities are frequently encountered. This article presents a case of a child who presented with compl...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-007-0663-0
更新日期：2008-11-01 00:00:00
abstract：:Two unique associations of disease with Escherichia coli O157:H7 are presented. These cases broaden the spectrum of disease associated with this organism which currently includes bloody and non-bloody diarrhoea, haemolytic-uraemic syndrome, and thrombotic thrombocytopenic purpura. ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02106287
更新日期：1990-01-01 00:00:00
abstract：:Acid-base disturbances have been usually evaluated with the traditional Henderson-Hasselbach method and Stewart's physiochemical approach by quantifying anions of tissue acids (TA). It is hypothesized that an increase in tissue acids during metabolic acidosis would cause a compensatory decrease in the plasma chloride ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-011-1666-4
更新日期：2012-06-01 00:00:00
abstract：:Sweet syndrome, also referred to as acute febrile neutrophilic dermatosis, is characterized by tender, red inflammatory nodules or papules that occur in association with infection, malignancy, connective tissue disease, or following exposure to certain drugs. Although drug-induced Sweet syndrome is rare, granulocyte c...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-010-1201-z
更新日期：2010-12-01 00:00:00
abstract：UNLABELLED:Complementary/alternative medicine (CAM) has become an important topic, not least because of its popularity with patients. This systematic review is aimed at summarising the data known about CAM use in paediatric populations. A thorough search strategy was designed to identify all surveys on the prevalence o...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s004310051000
更新日期：1999-01-01 00:00:00
abstract：UNLABELLED:The purpose of this study was to assess how much of the variance in intellectual outcome at 2 and 6 years of age could be attributed to treatment variables in children with congenital hypothyroidism, and which of the parameters used for monitoring treatment predicted later development. Forty-five children, e...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01955261
更新日期：1996-05-01 00:00:00
abstract：:Pulmonary arterial hypertension is characterised by the presence of pulmonary hypertension (mean pulmonary artery pressure >25 mmHg at rest or >30 mmHg during exercise ) and normal pulmonary wedge pressure (<12 mmHg). Several risk factors for pulmonary arterial hypertension have been described. In the absence of any f...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-002-1012-y
更新日期：2002-10-01 00:00:00
abstract：UNLABELLED:Delta1-pyrroline-5-carboxylate synthase (P5CS) catalyses the reduction of glutamate to Delta1-pyrroline-5-carboxylate, a critical step in the biosynthesis of proline, ornithine and arginine. Recently, we reported a newly recognised inborn error due to deficiency of P5CS in two sibs, one presenting at birth w...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-004-1545-3
更新日期：2005-01-01 00:00:00
abstract：UNLABELLED:An 8-year-old boy with frequently recurring pancreatitis-like abdominal pain, Fredrickson type V dyslipidaemia, and significantly decreased post-heparin plasma lipoprotein lipase (LPL) activity is described. In order to exclude familial LPL deficiency, the complete LPL coding gene sequence was analysed revea...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF01957148
更新日期：1996-08-01 00:00:00
abstract：UNLABELLED:To investigate the toxic effect of tobacco smoke on the fetus, we measured in cord blood the concentrations of alpha-fetoprotein (AFP), the principal serum protein in early ontogenic development, and erythropoietin (EPO), as an index of chronic fetal hypoxia. A total of 103 consecutively enrolled term newbor...
journal_title：European journal of pediatrics
pub_type： 临床试验,杂志文章
doi：10.1007/s004310051152
更新日期：1999-07-01 00:00:00
abstract：UNLABELLED:To examine the value of surfactant protein D and KL-6 as markers for the diagnosis and the severity of interstitial pneumonia caused by measles infection, surfactant protein D, KL-6 and lactic acid dehydrogenase were measured serially in three patients with measles complicated by interstitial pneumonia as co...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310100763
更新日期：2001-07-01 00:00:00
abstract：UNLABELLED:Disseminated atypical mycobacterium infection is essentially reported in cellular immunodeficient children. Cell-mediated immunity including cytokines like tumour necrosis factor alpha (TNF) and gamma interferon (IFN) is the most important factor allowing control of the dissemination of Mycobacterium. We rep...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310050583
更新日期：1997-03-01 00:00:00
abstract：:The main ethical imperative of all paediatric actions is the demand to do everything "in the best interests of children". Relevant guidelines can be derived from the UN Declaration on the Rights of Children, whereupon every child has the fundamental right to life and dignity, and is entitled to optimal medical care. P...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-005-0002-2
更新日期：2006-02-01 00:00:00
abstract：:One year's experience in screening for congenital hypothyroidism in Greece is reported. Thyroid stimulating hormone (TSH) determination by a radioimmunoassay on dried blood spots was selected as the screening method. During the first year of screening 75,879 newborn infants were tested from Guthrie blood spots taken o...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00441314
更新日期：1981-10-01 00:00:00
abstract：:All 270 patients presenting with Henoch-Schönlein Purpura over a 13-year period from a total childhood population of 155,000 were studied. This is an incidence of 13.5/100,000 children per year. Fifty-five (20%) were found to have initial evidence of renal involvement, and were re-examined at a mean of 8.3 years later...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00442205
更新日期：1988-02-01 00:00:00
