Why did they change that? Practical implications of the evolving classification of neuroendocrine tumours of the gastrointestinal tract.

abstract：:Immunohistochemical studies on renal biopsies from eight patients with various types of glomerulonephritis showed that the interstitial foam cells belonged to the monocyte-macrophage lineage. There was a strong association between hypercholesterolaemia and the presence of renal interstitial foam cells. ...

journal_title：Histopathology

authors： Franco M,Schmitt F,Rejaili WA,Viero RM,Bacchi CE

更新日期：1992-02-01 00:00:00

abstract：AIMS:In T cells, protein kinase C (PKC) theta plays a major role in T-cell receptor (TCR)-mediated activation of a novel nuclear factor (NF)-kappaB pathway that involves phosphorylation of p65 at serine 536 (Pp65(Ser536)). Bcl-10 acts along the same pathway downstream of PKC theta to activate NF-kappaB. The aim was to ...

journal_title：Histopathology

authors： Briones J,Moga E,Espinosa I,Vergara C,Alvarez E,Villa J,Bordes R,Delgado J,Prat J,Sierra J

更新日期：2009-03-01 00:00:00

abstract：:Aneuploidy is an important prognostic factor in many cancers. Chromosome 1 abnormalities are present in most breast carcinomas. These may be part of a non-specific increase in DNA (aneuploid status) or represent a restricted chromosomal abnormality. In 16 breast carcinomas we compared chromosome 1 aneusomy with ploidy...

journal_title：Histopathology

authors： Harrison MM,Magee HM,O'Loughlin JF,Gorey TF,Coyne JD,Dervan PA

更新日期：1997-03-01 00:00:00

abstract：AIMS:To describe a case of rhabdomyomatosis of the lung unassociated with other external or visceral malformations in a newborn infant. METHODS AND RESULTS:A 26 weeks gestation newborn male with no relevant medical or family history presented a well-circumscribed solid area in the posterior mediastinum occupying the u...

journal_title：Histopathology

authors： Hardisson D,García-Jiménez JA,Jiménez-Heffernan JA,Nistal M

更新日期：1997-11-01 00:00:00

abstract：:Upper gastrointestinal endoscopic examination of 40 patients on immunosuppressive therapy after successful kidney transplantation revealed a duodenal ulcer in four cases and duodenal erosions in six. Between four and six biopsies were collected from the antral and the fundal mucosa in each case and from the duodenal m...

journal_title：Histopathology

authors： Franzin G,Musola R,Mencarelli R

更新日期：1982-07-01 00:00:00

abstract：AIMS:Biphenotypic sinonasal sarcoma (SNS) is a locally aggressive tumour that occurs in the sinonasal region. PAX3-MAML3 has recently been identified as a recurrent fusion gene event in this entity; however, a subset of tumours harbour alternative PAX3 rearrangement without the involvement of MAML3. In this study we so...

journal_title：Histopathology

authors： Fritchie KJ,Jin L,Wang X,Graham RP,Torbenson MS,Lewis JE,Rivera M,Garcia JJ,Schembri-Wismayer DJ,Westendorf JJ,Chou MM,Dong J,Oliveira AM

更新日期：2016-12-01 00:00:00

abstract：AIMS:We report a case study to elucidate the pathogenesis of polyarteritis nodosa (PAN) type vasculitis, a rare complication of familial mediterranean fever (FMF). METHODS AND RESULTS:A woman with amyloidosis complicating FMF underwent a cadaveric renal transplantation and 5 years later suffered an acute myocardial in...

journal_title：Histopathology

authors： Serrano R,Martínez MA,Andrés A,Morales JM,Samartin R

更新日期：1998-08-01 00:00:00

abstract：AIMS:Glutamate receptor antagonists have failed clinical stroke trials and it has been proposed that the action of N-methyl D-aspartate receptors is necessary for neuronal survival. Thus, excitatory amino acid transporters (EAATs) might be a promising therapeutic target. The aim of this study was to investigate glial e...

journal_title：Histopathology

authors： Beschorner R,Simon P,Schauer N,Mittelbronn M,Schluesener HJ,Trautmann K,Dietz K,Meyermann R

更新日期：2007-06-01 00:00:00

abstract：:To elucidate the role of cell turnover in primary gastric B-cell non-Hodgkin's lymphomas we studied tissue samples of 72 patients-26 small cell (25 MALT lymphomas) and 46 large cell (31 MALT lymphomas). Proliferation indices and apoptotic indices were measured by Mib-1 expression and terminal deoxynucleotidyltransfera...

journal_title：Histopathology

authors： Gisbertz IA,Schouten HC,Bot FJ,Arends JW

更新日期：1997-02-01 00:00:00

abstract：AIMS:To describe a tumour with morphological and immunophenotypic characteristics of epithelioid variant of pleomorphic liposarcoma. Pleomorphic liposarcoma is a very rare variant of liposarcoma defined morphologically by the presence of pleomorphic lipoblasts showing peculiar epithelial-like features that can be confu...

journal_title：Histopathology

authors： De Cecco L,Gariboldi M,Reid JF,Lagonigro MS,Tamborini E,Albertini V,Staurengo S,Pilotti S,Pierotti MA

更新日期：2005-03-01 00:00:00

abstract：:We report a case of an adrenal lipoma, a very rare lesion first described in 1899 and of which a total of six cases have previously been reported (Lange 1966, Page, De Lellis & Hough 1986). Five of these cases were found incidentally at post mortem. In one case an acute hypertensive episode intra-operatively simulated...

journal_title：Histopathology

authors： Avinoach I,Robinson CR,Avinoah E,Peiser J

更新日期：1989-08-01 00:00:00

abstract：AIMS:In this study, we aimed to investigate the clinicopathological features of CD4+ and/or CD56+ immature haematolymphoid malignancy (iHLM), including blastic plasmacytoid dendritic cell neoplasm (BPDCN). METHODS AND RESULTS:We analysed the clinicopathological features of 46 patients diagnosed consecutively with CD4+...

journal_title：Histopathology

authors： Suzuki Y,Kato S,Kohno K,Satou A,Eladl AE,Asano N,Kono M,Kato Y,Taniwaki M,Akiyama M,Nakamura S

更新日期：2017-12-01 00:00:00

abstract：AIMS:Glypican 3 (GPC3) has been reported to be overexpressed in yolk sac tumour (YST), but the sensitivity has not been compared with alpha-fetoprotein (AFP). YST can form numerous growth patterns and the expression of GPC3 in these patterns has not been studied. The aim was to address these aspects. METHODS AND RESUL...

journal_title：Histopathology

authors： Zynger DL,McCallum JC,Luan C,Chou PM,Yang XJ

更新日期：2010-05-01 00:00:00

abstract：:Two cases of papillary and cystic neoplasm of the pancreas (PCN) occurring in 17 and 21 year old women are reported with ultrastructural and immunohistochemical findings. A review of the English literature shows that although potentially malignant, PCN, which occurs mainly in young women, is amenable to surgical cure....

journal_title：Histopathology

authors： Learmonth GM,Price SK,Visser AE,Emms M

更新日期：1985-01-01 00:00:00

abstract：AIMS:Because of its efficacy, oxaliplatin (OX) is increasingly used as a chemotherapeutic agent in the treatment of colorectal liver metastases (CRLM). Oxaliplatin-associated liver toxicity has been reported and can affect clinical practice, but studies on its prevalence and a full pathological description are lacking....

journal_title：Histopathology

authors： Rubbia-Brandt L,Lauwers GY,Wang H,Majno PE,Tanabe K,Zhu AX,Brezault C,Soubrane O,Abdalla EK,Vauthey JN,Mentha G,Terris B

更新日期：2010-03-01 00:00:00

abstract：AIMS:Five cases of a characteristic low-grade thymic epithelial tumour are described that we suggest calling metaplastic carcinoma of the thymus. METHODS AND RESULTS:The patients' ages ranged from 44 to 71 (mean 56.2) years. Four of the patients were male. Three of five tumours showed invasion into mediastinal fat or ...

journal_title：Histopathology

authors： Yoneda S,Marx A,Heimann S,Shirakusa T,Kikuchi M,Müller-Hermelink HK

更新日期：1999-07-01 00:00:00

abstract：AIMS:AP2alpha (TFAP2A) and AP2gamma (TFAP2G) transcription factors have been implicated in the control of proliferation, differentiation and apoptosis of normal breast epithelium and in breast cancer. The aim of this study was to provide a comprehensive analysis of the expression patterns of TFAP2A and TFAP2G in the de...

journal_title：Histopathology

authors： Friedrichs N,Steiner S,Buettner R,Knoepfle G

更新日期：2007-12-01 00:00:00

abstract：:Morphometric methods were applied to predict the clinical course of individual patients with breast cancer. Measurement of tumour diameter, assessment of mitotic and cellular indices, and quantitative microscopy of nuclear features were assessed together with nuclear features and histological grades. Of the tumours fr...

journal_title：Histopathology

authors： Baak JP,Kurver PH,De Snoo-Niewlaat AJ,De Graef S,Makkink B,Boon ME

更新日期：1982-05-01 00:00:00

abstract：:Nine cases of Mullerian adenosarcoma of the uterine body, first defined in 1974 by Clement & Scully, are described. The tumour usually occurs in elderly women and appears macroscopically as a polypoid mass filling the uterine cavity. Histologically these neoplasms are characterized by having a benign epithelial compon...

journal_title：Histopathology

authors： Fox H,Harilal KR,Youell A

更新日期：1979-05-01 00:00:00

abstract：AIMS:To develop a method to preserve lipids in formalin-fixed tissues for staining in paraffin sections, and to illustrate its use in lung and brain of a fat embolism case, and in examples of fatty liver and atheroma. METHODS AND RESULTS:A saturated solution of linoleic acid in 70% ethylene glycol was prepared and tis...

journal_title：Histopathology

authors： Tracy RE,Walia P

更新日期：2002-07-01 00:00:00

abstract：:Tumour budding in colorectal cancer, defined as single tumour cells or small clusters containing four or fewer tumour cells, is a robust and independent biomarker of aggressive tumour biology. On the basis of published data in the literature, the evidence is certainly in favour of reporting tumour budding in routine p...

journal_title：Histopathology

authors： Studer L,Blank A,Bokhorst JM,Nagtegaal ID,Zlobec I,Lugli A,Fischer A,Dawson H

更新日期：2020-10-01 00:00:00

abstract：AIM:Special AT-rich sequence-binding protein 1 (SATB1) is a cell type-specific matrix attachment region binding protein, functioning as a global genome organizer. This study aims to investigate the expression pattern and the prognostic value of SATB1 in colorectal cancer. METHODS AND RESULTS:Prospectively collected da...

journal_title：Histopathology

authors： Al-Sohaily S,Henderson C,Selinger C,Pangon L,Segelov E,Kohonen-Corish MR,Warusavitarne J

更新日期：2014-08-01 00:00:00

abstract：AIMS:The diagnosis of epithelioid haemangioendothelioma (EHE) is usually straightforward, based on characteristic histological features. However, it is sometimes difficult to differentiate EHE from a variety of other tumours with epithelioid morphology. The WW domain-containing transcription regulator 1-calmodulin-bind...

journal_title：Histopathology

authors： Shibuya R,Matsuyama A,Shiba E,Harada H,Yabuki K,Hisaoka M

更新日期：2015-12-01 00:00:00

abstract：AIMS:Pleomorphic lobular carcinoma (PLC) is an aggressive variant of invasive lobular carcinoma. The aim of this study was to redefine PLC in terms of molecular classification. METHODS AND RESULTS:Cases of PLC were selected between 1995 and 2010. Key clinicopathological features were recorded for most of the patients....

journal_title：Histopathology

authors： Monhollen L,Morrison C,Ademuyiwa FO,Chandrasekhar R,Khoury T

更新日期：2012-09-01 00:00:00

abstract：AIMS:We compared the immunohistochemical profiles of the rete ovarii and endometriosis in order to identify a panel which distinguishes between these structures. The immune profiles of the epoophoron, Fallopian tube and ovarian surface epithelium were also studied. MATERIALS AND METHODS:Twenty-four women with no evide...

journal_title：Histopathology

authors： Russo L,Woolmough E,Heatley MK

更新日期：2000-07-01 00:00:00

abstract：AIMS:We investigated the phenotypic and cytotoxic characteristics of different types of peripheral T-cell and NK-cell lymphomas and correlated the findings of cytotoxic phenotype with Epstein-Barr virus (EBV) association. METHODS AND RESULTS:Eighty cases of peripheral T-cell and NK-cell lymphomas, classified according...

journal_title：Histopathology

authors： Chan AC,Ho JW,Chiang AK,Srivastava G

更新日期：1999-01-01 00:00:00

abstract：AIMS:Although delayed hypopituitarism is a common complication of conventional radiotherapy of sellar tumours, histological changes that may account for it have been rarely reported. To elucidate the changes, hypofunctional pituitary glands following irradiation were studied. METHODS AND RESULTS:Two pituitary glands o...

journal_title：Histopathology

authors： Nishioka H,Ito H,Haraoka J,Hirano A

更新日期：2001-06-01 00:00:00

abstract：AIMS:Serum amyloid A is an acute phase reactant that is produced by hepatocytes in response to either inflammatory or neoplastic conditions. Because inflammatory adenomas produce this protein, serum amyloid A immunohistochemistry has been used in the evaluation of hepatocellular neoplasms. However, studies evaluating t...

journal_title：Histopathology

authors： Piotti KC,Yantiss RK,Chen Z,Jessurun J

更新日期：2016-12-01 00:00:00

abstract：AIMS:To clarify the lineage-specific carcinogenesis of gland-forming gastric neoplasms, by characterizing mucin phenotypes and proliferation patterns immunohistochemically using monoclonal antibodies against MUC2, MUC5AC, MUC6, CD10 and Ki67. METHODS AND RESULTS:We analysed 49 gland-forming intramucosal neoplasms, inc...

journal_title：Histopathology

authors： Nishimura R,Mukaisho K,Yamamoto H,Sonoda A,Andoh A,Fujiyama Y,Hattori T,Sugihara H

更新日期：2013-11-01 00:00:00

abstract：:One hundred and eighty-seven operable lung tumours were immunostained with the monoclonal antibody Ki-67 and divided into groups of high, moderate or low proliferation. Patients have been followed clinically for up to 7 years to ascertain whether this immunocytochemical measurement reflected tumour behaviour in terms ...

journal_title：Histopathology

authors： Tungekar MF,Gatter KC,Dunnill MS,Mason DY

更新日期：1991-12-01 00:00:00