Massive metoprolol ingestion associated with a fatality--a case report.

Abstract:

:An unusual fatality involving a 26-year-old male who intentionally ingested approximately 10 g of metoprolol is presented. Autopsy findings revealed foreign material in the gastric content with an acute thrombosis of the left anterior descending coronary artery. Microscopic studies showed evidence of an extremely early infarct. Metoprolol concentrations in the blood, liver, gastric content, and urine are reported by both capillary gas chromatography and ultraviolet spectrophotometric analysis. A review of the literature confirmed that little information has been published concerning intoxication with this drug.

journal_name

J Forensic Sci

authors

Riker CD,Wright RK,Matusiak W,de Tuscan BE

subject

Has Abstract

pub_date

1987-09-01 00:00:00

pages

1447-52

issue

5

eissn

0022-1198

issn

1556-4029

journal_volume

32

pub_type

杂志文章,评审
  • Domestic Homicide: Neuropsychological Profiles of Murderers Who Kill Family Members and Intimate Partners.

    abstract::Domestic homicide is the most extreme form of domestic violence and one of the most common types of homicide. The objective was to examine differences between spontaneous domestic homicide and nondomestic homicide offenders regarding demographics, psychiatric history, crime characteristics, and neuropsychological stat...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/1556-4029.12908

    authors: Hanlon RE,Brook M,Demery JA,Cunningham MD

    更新日期:2016-01-01 00:00:00

  • Sex assessment from metacarpals of the human hand.

    abstract::Discriminant functions designed for the determination of sex from metacarpal measurements are presented. Three samples of metacarpal specimens were employed in the analysis; one consisting of 212 individuals from the Terry Collection, one of 33 individuals from the Royal Free Medical School in London, and finally, 40 ...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:

    authors: Falsetti AB

    更新日期:1995-09-01 00:00:00

  • Determining the Method Threshold of Identification via Gas Chromatography-Mass Spectrometry of Weathered Gasoline Extracted from Burnt Nylon Carpet.

    abstract::The Organization of Scientific Area Committees defines threshold of identification as the minimum concentration of ignitable liquid identifiable from gas chromatographic-mass spectrometry data using accepted pattern identification criteria. We propose a method for determining this threshold for gasoline based on base ...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/1556-4029.13983

    authors: Hondrogiannis EM,Newton C,Alibozek R

    更新日期:2019-07-01 00:00:00

  • Strontium isotope composition of skeletal material can determine the birth place and geographic mobility of humans and animals.

    abstract::The Sr isotope composition measured in skeletal elements (e.g., bone, teeth, or antlers) can be used to infer the geographic region that an animal or human inhabited, because different regions tend to have distinct Sr isotope compositions, and natural variations in the relative abundance of Sr isotopes are not changed...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:

    authors: Beard BL,Johnson CM

    更新日期:2000-09-01 00:00:00

  • The detection of psilocin in human urine.

    abstract::Pharmacokinetic studies of psilocybin in humans have shown the rapid dephosphorylation of psilocybin to psilocin with further conversion to 4-hydroxy-tryptophole (4HT) and 4-hydroxyindole-3-acetic acid (4HIAA) in plasma. Our study shows that psilocin also undergoes conjugation and can be found in the urine as the psil...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:

    authors: Grieshaber AF,Moore KA,Levine B

    更新日期:2001-05-01 00:00:00

  • An improved means of enzyme typing of hair roots using isoelectric focusing.

    abstract::An improved method of grouping hair, based on the alleles of PGM observed by isoelectric focusing, has been described. The increased discriminating power of this system (0.77) compared to that obtained by the starch gel technique (0.55) provides a new and more sensitive means of typing hair. ...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:

    authors: Burgess RM,Sutton JG,Whitehead PH

    更新日期:1979-04-01 00:00:00

  • Enzymatic detection of γ-hydroxybutyrate using aldo-keto reductase 7A2.

    abstract::Gamma-hydroxybutyrate (GHB) is a prescribed medication as well as a drug of abuse. Its detection in various matrices for in-field forensic scientists remains a challenge. We have developed an assay that uses aldo-keto reductase 7A2 (AKR7A2) for the specific determination of GHB in various drinks. AKR7A2 was purified u...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/j.1556-4029.2010.01694.x

    authors: Bendinskas K,Sattelberg P,Crossett D,Banyikwa A,Dempsey D,MacKenzie JA

    更新日期:2011-05-01 00:00:00

  • The contribution of trace elements from smokeless powder to post firing residues.

    abstract::The smokeless powders in 22 kinds of ammunitions seized from one of the Japanese gang groups were analyzed by scanning electron microscopy/energy dispersive X-ray microanalysis (SEM/EDX). Copper(Cu), sulfur(S), potassium(K), silicon(Si), aluminum(Al), calcium(Ca), iron(Fe), chlorine(Cl), and barium(Ba) were detected. ...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:

    authors: Miyauchi H,Kumihashi M,Shibayama T

    更新日期:1998-01-01 00:00:00

  • Sex- and Size-Related Patterns of Carrion Visitation in Necrodes littoralis (Coleoptera: Silphidae) and Creophilus maxillosus (Coleoptera: Staphylinidae).

    abstract::The estimation of postmortem interval (PMI) based on successional patterns of adult insects is largely limited, due to the lack of potential PMI markers. Sex and size of adult insects could be easily used for such estimation. In this study, sex- and size-related patterns of carrion attendance by adult insects were ana...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/1556-4029.13376

    authors: Mądra-Bielewicz A,Frątczak-Łagiewska K,Matuszewski S

    更新日期:2017-09-01 00:00:00

  • The Value of Outsourcing Selected Cases in a Medical Examiner Population: A 10-Year Experience.

    abstract::Due to increasing caseloads and inadequate staffing, the burden on Coroner/Medical Examiner Offices to comply with recommended autopsy limits for forensic pathologists (FPs) has been difficult. Since 2006, pathologists at the University of Alabama at Birmingham have performed select autopsies for the Alabama Departmen...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/1556-4029.13269

    authors: McCleskey BC,Reilly SD,Atherton D

    更新日期:2017-01-01 00:00:00

  • Burden of neurodegenerative diseases in a cohort of medical examiner subjects.

    abstract::Here we report studies of the burden of neurodegenerative neuropathologies in a cohort of Medical Examiner (ME) subjects from the County of Santa Clara (California) to determine if this unique population of decedents manifested evidence of neurodegeneration that might underlie causes of death seen in an ME practice. W...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/j.1556-4029.2010.01347.x

    authors: Uryu K,Haddix T,Robinson J,Nakashima-Yasuda H,Lee VM,Trojanowski JQ

    更新日期:2010-05-01 00:00:00

  • TrueAllele(®) Genotype Identification on DNA Mixtures Containing up to Five Unknown Contributors.

    abstract::Computer methods have been developed for mathematically interpreting mixed and low-template DNA. The genotype modeling approach computationally separates out the contributors to a mixture, with uncertainty represented through probability. Comparison of inferred genotypes calculates a likelihood ratio (LR), which measu...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/1556-4029.12788

    authors: Perlin MW,Hornyak JM,Sugimoto G,Miller KW

    更新日期:2015-07-01 00:00:00

  • In the eye of the beholder: sex and race estimation using the human orbital aperture.

    abstract::From the works of Broca and Krogman to modern-day Jantz and Buikstra, the orbit has been used for both quantitative and qualitative sex and race estimation. This study evaluates the practical value of these estimations. Orbital height and breadth were measured to determine the orbital index and assess differences betw...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/j.1556-4029.2011.01864.x

    authors: Husmann PR,Samson DR

    更新日期:2011-11-01 00:00:00

  • Mitochondrial DNA control region polymorphism in the population of Alagoas state, north-eastern Brazil.

    abstract::The sequences of the two hypervariable (HV) segments of the mitochondrial DNA (mtDNA) control region were determined in 167 randomly selected, unrelated individuals living in the state of Alagoas, north-eastern Brazil. One hundred and forty-five different haplotypes, associated with 139 variable positions, were determ...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/j.1556-4029.2007.00619.x

    authors: Barbosa AB,da Silva LA,Azevedo DA,Balbino VQ,Mauricio-da-Silva L

    更新日期:2008-01-01 00:00:00

  • Sudden death by inhalation of cyclopropane.

    abstract::This paper reports the case of a 22-year-old white male who was found dead in a storage room as a result of a fatal ingestion of cyclopropane. Cyclopropane is a sweet-smelling, irritating gas. Autopsy findings revealed congestion and hemorrhagic edema of the lungs, congestion of the trachea, and early autolysis. Cyclo...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:

    authors: Krause JG,McCarthy WB

    更新日期:1989-07-01 00:00:00

  • Spatial and temporal influences on bacterial profiling of forensic soil samples.

    abstract::Bacterial content may be helpful in differentiating forensic soil samples; however, the effectiveness of bacterial profiling depends on several factors, including uniqueness among different habitat types, the level of heterogeneity within a habitat, and changes in bacterial communities over time. To examine these, soi...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/j.1556-4029.2008.00728.x

    authors: Meyers MS,Foran DR

    更新日期:2008-05-01 00:00:00

  • Iatrogenic Burns of the Neckline in a Patient with Tetraparesis During Tracheotomy.

    abstract::The paper presents a case of an atypical iatrogenic complication after tracheotomy analyzed on the basis of the case dossier materials submitted to the authors by the court of justice to prepare a forensic medical opinion concerning the correctness of the medical procedure. A 37-year-old woman was brought by the ambul...

    journal_title:Journal of forensic sciences

    pub_type:

    doi:10.1111/1556-4029.13240

    authors: Smędra A,Meissner E,Barzdo M,Grabowski P,Kartasiński M,Krajewski W,Berent J

    更新日期:2017-01-01 00:00:00

  • Postmortem forensic toxicology of selective serotonin reuptake inhibitors: a review of pharmacology and report of 168 cases.

    abstract::This paper reviews the complex pharmacology of the new class of antidepressant medications exhibiting selective inhibition of serotonin reuptake. The four selective serotonin reuptake inhibitors (SSRIs) considered--fluoxetine, fluvoxamine, sertraline and paroxetine--can result in toxicity and death through contributin...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Goeringer KE,Raymon L,Christian GD,Logan BK

    更新日期:2000-05-01 00:00:00

  • The use of histomorphology to estimate age.

    abstract::The purpose of this paper is to discuss some of the major factors that can affect age-at-death predictions when using histomorphological methods. Although evidence suggests that some of the currently available methods are more reliable and accurate, and there are a number of factors other than chronological age that c...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章,评审

    doi:

    authors: Stout SD

    更新日期:1988-01-01 00:00:00

  • A new anti-forensic scheme--hiding the single JPEG compression trace for digital image.

    abstract::To prevent image forgeries, a number of forensic techniques for digital image have been developed that can detect an image's origin, trace its processing history, and can also locate the position of tampering. Especially, the statistical footprint left by JPEG compression operation can be a valuable source of informat...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/1556-4029.12618

    authors: Cao Y,Gao T,Sheng G,Fan L,Gao L

    更新日期:2015-01-01 00:00:00

  • Prediction of stature based on radiographic measurements of cadaver long bones: a study of the Croatian population.

    abstract::We tested a new approach to the stature prediction that could be used in the identification process of human skeletal remains of unknown identity. The stature of 19 female and 21 male adult cadavers was measured within 24 h after death and considered to be equal to the living stature. The antero-posterior radiographs ...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/j.1556-4029.2007.00419.x

    authors: Petrovecki V,Mayer D,Slaus M,Strinović D,Skavić J

    更新日期:2007-05-01 00:00:00

  • Gunshot residue in Chicago police vehicles and facilities: an empirical study.

    abstract::Suspects in shooting investigations in Chicago are routinely transported in department vehicles and detained in department facilities prior to gunshot residue (GSR) evidence collection. The GSR test results are used to associate the suspect with primary exposure to GSR. The potential for these vehicles and facilities ...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/j.1556-4029.2007.00457.x

    authors: Berk RE,Rochowicz SA,Wong M,Kopina MA

    更新日期:2007-07-01 00:00:00

  • Comparison of DNA yield and STR profiles from the diaphysis, mid-diaphysis, and metaphysis regions of femur and tibia long bones.

    abstract::DNA testing of human bones is performed for identification when there is no remaining soft tissue, which often means the samples are old or environmentally compromised. Under these circumstances, it can be difficult to obtain a STR DNA profile. It is important to recover the highest quantity and quality of DNA for STR...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/1556-4029.14657

    authors: Klavens A,Kollmann DD,Elkins KM,Zeller CB

    更新日期:2020-12-28 00:00:00

  • HumCD4--validation of a STR system for forensic purposes in an Austrian Caucasian population sample.

    abstract::The short tandem repeat system HumCD4 was amplified by the polymerase chain reaction (PCR) on blood samples from 304 unrelated Austrian Caucasians and analyzed by horizontal, non-denaturing polyacrylamide electrophoresis. The mean exclusion chance was 0.417, the discriminating power 0.850 and the heterozygosity rate 0...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:

    authors: Klintschar M,Crevenna R

    更新日期:1997-09-01 00:00:00

  • Preservation of human tissue immersed for five years in fresh water of known temperature.

    abstract::Two human bodies were recovered from the waters of the Duluth, Minnesota harbor. Extensive adipocere formation resulted in remarkable preservation of gross anatomic features of internal organs. Total time of immersion could be precisely estimated at five years. Water temperature during those five years could also be a...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:

    authors: Cotton GE,Aufderheide AC,Goldschmidt VG

    更新日期:1987-07-01 00:00:00

  • Analysis of condom lubricants for forensic casework.

    abstract::The detection of DNA is inhibited in cases of sexual assault involving condom use. Trace evidence, including condom lubricant residues, provides crucial associative evidence in such cases. The existing Fourier transform infrared spectroscopy (FTIR) methods for lubricant analysis and detection are limited with regard t...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/j.1556-4029.2007.00411.x

    authors: Campbell GP,Gordon AL

    更新日期:2007-05-01 00:00:00

  • Infrared spectra of U.S. automobile original finishes (1998-2000). IX. identification of bismuth oxychloride and silver/white mica pearlescent pigments using extended range FT-IR spectroscopy, XRF spectrometry, and SEM/EDS analysis.

    abstract::Bismuth oxychloride (BiOCl) was the first viable synthetic pearl pigment developed 50 years ago. It was only used for a limited time period in automotive paint (model years 1998-2000), serving to produce luster for a single Chrysler black metallic color. Identification of this pigment in an unknown automotive paint ca...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/1556-4029.12414

    authors: Suzuki EM

    更新日期:2014-09-01 00:00:00

  • Comparison of GC-MS and EIA results for the analysis of methadone in oral fluid.

    abstract::The purpose of these studies was to evaluate the performance characteristics of the Cozart Microplate Enzyme Immunoassay (EIA) for the determination of methadone in oral fluid from patients in a drug misuse treatment program. Oral fluid specimens were collected using the Cozart RapiScan Collection system from 198 dono...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:

    authors: Cooper G,Wilson L,Reid C,Baldwin D,Hand C,Spiehler V

    更新日期:2005-07-01 00:00:00

  • Homicide by intravenous injection of naphtha.

    abstract::A case of homicide by the intravenous injection of Energine, a petroleum distillate spot remover, is presented. This case is the only known homicide committed with naphtha. This elderly man had severe natural disease in addition to chest trauma sustained in the assault leading to death; however, the rapid injection of...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:

    authors: Case ME,Poklis A,Mackell MA

    更新日期:1985-01-01 00:00:00

  • Validation of reduced-scale reactions for the Quantifiler Human DNA kit.

    abstract::Accurate quantification of DNA samples is an important step in obtaining accurate and reproducible short tandem repeat (STR) profiles. Quantitative real-time-PCR has improved the speed and accuracy of DNA quantification over earlier methods, albeit at significantly greater cost per reaction. Here, the performance of r...

    journal_title:Journal of forensic sciences

    pub_type: 杂志文章

    doi:10.1111/j.1556-4029.2007.00525.x

    authors: Westring CG,Kristinsson R,Gilbert DM,Danielson PB

    更新日期:2007-09-01 00:00:00