Abstract：
:Here we report studies of the burden of neurodegenerative neuropathologies in a cohort of Medical Examiner (ME) subjects from the County of Santa Clara (California) to determine if this unique population of decedents manifested evidence of neurodegeneration that might underlie causes of death seen in an ME practice. We found that 13% of the brains from ME cases showed significant tau pathology, including 55% of those 65 years old and older and 63% of those 70 years old and older. The histochemical and immunohistochemical findings were consistent with Alzheimer's disease (AD) in 7 subjects and frontotemporal lobar degeneration (FTLD) tauopathy type in six cases. There were no cases of Parkinson's disease, dementia with Lewy Bodies or other neurodegenerative conditions. Our study suggests that decedents >65 years of age in an ME practice are afflicted by common causes of dementia such as AD and FTLD which could contribute wholly or in part to their causes of death.
journal_name
J Forensic Scijournal_title
Journal of forensic sciencesauthors
Uryu K,Haddix T,Robinson J,Nakashima-Yasuda H,Lee VM,Trojanowski JQdoi
10.1111/j.1556-4029.2010.01347.xsubject
Has Abstractpub_date
2010-05-01 00:00:00pages
642-5issue
3eissn
0022-1198issn
1556-4029pii
JFO1347journal_volume
55pub_type
杂志文章abstract：:Larvae of Parasarcophaga ruficornis (Fabricius) (Diptera: Sarcophagidae) were reared on tissues from rabbits administered different dosages of methamphetamine to study the effects of this drug on development of this species. The rabbits were given 37.5, 71.4, and 142.9 mg of methamphetamine via ear vein infusion. From...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:From the works of Broca and Krogman to modern-day Jantz and Buikstra, the orbit has been used for both quantitative and qualitative sex and race estimation. This study evaluates the practical value of these estimations. Orbital height and breadth were measured to determine the orbital index and assess differences betw...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2011.01864.x
更新日期：2011-11-01 00:00:00
abstract：:Little is known about to what extent the events surrounding death can be reliably reconstructed from blunt force trauma analysis alone. In this study, we reconstruct circumstances of death from a blind blunt force trauma analysis using a sample of 21 individuals of known death circumstances, obtained from two identifi...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.13128
更新日期：2016-11-01 00:00:00
abstract：:In this paper, a novel three-dimensional transformation method for vehicle license plate number recognition is proposed. This method provides an efficient solution to normalize skew distorted vehicle license plate images. The Hough transform is used to estimate the license plate position and the normalization angle. A...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2002-05-01 00:00:00
abstract：:Age estimation methods are often based on the age-related morphological changes of the auricular surface and the pubic bone. In this study, a mathematical approach to quantify these changes has been tested analyzing the curvature variation on 3D models from CT and laser scans. The sample consisted of the 24 Suchey-Bro...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12689
更新日期：2015-05-01 00:00:00
abstract：:Stepwise multiple discriminant function analysis is used to establish classification functions for sex assessment of North American white femora. The functions correctly assign sex for 82% of a sample consisting of 85 femora of verified age, sex, and race, and for a similarly verified test sample of 30. The objectives...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1982-04-01 00:00:00
abstract：:The aims of this study were to enable geometric morphometric sex classification using tibial proximal and distal sexual dimorphism and to evaluate the secular trend of tibial shape/form from the early 20th century to the present day. The study samples consisted of 61 adult tibias from an early 20th-century Czech popul...
journal_title：Journal of forensic sciences
pub_type： 历史文章,杂志文章
doi：10.1111/1556-4029.12641
更新日期：2015-01-01 00:00:00
abstract：:Elopements from psychiatric units are a frequent but usually low-grade risk. However, they are sometimes followed by harmful consequences, for which the psychiatrist and the hospital may be held liable. We describe management methods developed to reduce such liability. These include a structured observation system and...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Skin detail of the hand is used in photographic comparisons, yet its reliability has not been evaluated. This study examines a count-based method for documenting skin features. In Part I, 14 individuals counted skin features on 40 color images of the hand, three of which were repeated. An average correlation value of ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12824
更新日期：2015-11-01 00:00:00
abstract：:Owing to the scanty evidence on usefulness of information of appearance of gray hair for age estimation, this study was conducted to estimate age based on the appearance of gray hair on different body sites in a sample of autopsy cases in Sri Lanka. A descriptive cross-sectional study was conducted in Teaching Hospita...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.13375
更新日期：2017-07-01 00:00:00
abstract：:Allele frequencies for the loci HLA-DQA1, LDLR, GYPA, HBGG, D7S8, GC, and D1S80 were determined for a sample population of unrelated individuals from Slovenia. All loci meet Hardy-Weinberg expectations, except the loci GYPA (p = 0.041) and D1S80 (p = 0.009). There is little evidence for association of alleles among th...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2000-05-01 00:00:00
abstract：:Larvae and pupae of blow fly species are frequently used in postmortem interval estimation, their age indicating minimum time since death. Most studies have considered age estimation of larvae, neglecting study of pupae. Relative development of external pupal features is useful, but there are also internal changes dur...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2012.02196.x
更新日期：2013-01-01 00:00:00
abstract：:In the era of Daubert and other judicial rulings pertaining to the acceptability of forensic evidence, it is increasingly important that experts are able to testify that their methods have been scientifically tested and that error rates and other factors relating to reliability have been published. The purpose of this...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2003-11-01 00:00:00
abstract：:This paternity study was performed with trios in which the putative father was not the biological father (NBF), in order to evaluate the effectiveness of HLA-A and -B phenotyping for routine testing. All 372 generated trios had ABO, Rh, MNS, Kell, Duffy, Kidd and HLA (A and B) systems tested. HLA-A and -B phenotyping ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1993-11-01 00:00:00
abstract：:A 38-year-old nondiabetic female developed fatal hypoglycemia when chlorpropamide (Diabinese) was accidentally substituted for acetaminophen (Tylenol) with codeine no. 3 in a pharmacy dispensing error. When found, the patient's serum glucose was less than 20 mg/dL. The serum chlorpropamide level on hospital admission ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：:This paper reports the case of a 22-year-old white male who was found dead in a storage room as a result of a fatal ingestion of cyclopropane. Cyclopropane is a sweet-smelling, irritating gas. Autopsy findings revealed congestion and hemorrhagic edema of the lungs, congestion of the trachea, and early autolysis. Cyclo...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：:PSA is currently being used to detect and monitor quantitatively the development of prostate cancer by serum levels of PSA and has also been found to be present in high concentrations in semen. Elegantly simple, sensitive, and reproducible methods have been developed for analysis of the presence of PSA, including the ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1999-11-01 00:00:00
abstract：:This paper describes three recent false sexual assaults examined at the Victoria Forensic Science Centre laboratory where clothing damage analysis assisted in the resolution of the case. Suspected false reports of sexual assaults are often sensitive cases with little other forensic evidence. Any evidential value that ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2000-05-01 00:00:00
abstract：:Comparing skeletal structures between antemortem and postmortem chest radiographs is widely used by forensic specialists from many disciplines to positively identify unknown decedents. However, validity assessments of this method have been fairly limited. This study had three objectives: 1) to quantify the reliability...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2002-07-01 00:00:00
abstract：:A rapid and precise method for the isolation and identification of dihydrocodeine from urine is reported. The narcotic is isolated from urine using Sep-Pak C18 cartridges for cleanup, requiring less than 30 min for preparation. Identification is performed by gas chromatography/mass spectrometry. ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1987-03-01 00:00:00
abstract：:A sensitive, specific and simple color test for the improvised explosive urea nitrate is described. It is based on the formation of a red pigment upon the reaction between urea nitrate and p-dimethylaminocinnamaldehyde (p-DMAC) under neutral conditions. Urea itself, which is the starting material for urea nitrate, doe...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2005-05-01 00:00:00
abstract：:Illegal trade in snake parts has increased enormously. In spite of strict protection under wildlife act, a large number of snakes are being killed ruthlessly in India for venom and skin. Here, an interesting case involving confiscation of crystallized dried snake venom and subsequent DNA-based species identification i...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2011.02049.x
更新日期：2012-05-01 00:00:00
abstract：:This report describes the genetic identification of James "Earthquake McGoon" McGovern, a WWII fighter ace who perished in Laos while providing supplies to French troops during the French Indochina war. Because reference samples were unavailable for all of the potential casualties, testing of the entire mitochondrial ...
journal_title：Journal of forensic sciences
pub_type： 历史文章,杂志文章
doi：10.1111/j.1556-4029.2007.00506.x
更新日期：2007-09-01 00:00:00
abstract：:Using passive headspace concentration (ASTM E-1412) and gas chromatographic/mass spectrometric (GC/MS) analysis as described in ASTM E-1618, the authors have studied the volatile components detectable in several kinds of otherwise uncontaminated substrata, including clothing, shoes, household products, building materi...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：:Currently in the United States there is little direction for what constitutes sufficient guidelines for DNA mixture interpretation. While a standardized approach is not possible or desirable, more definition is necessary to ensure reliable interpretation of results is carried out. In addition, qualified DNA examiners ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2009.01046.x
更新日期：2009-07-01 00:00:00
abstract：:To obtain a reliable estimation on the yield of illicit indoor cannabis cultivation in The Netherlands, cannabis plants confiscated by the police were used to determine the yield of dried female flower buds. The developmental stage of flower buds of the seized plants was described on a scale from 1 to 10 where the val...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2006.00228.x
更新日期：2006-09-01 00:00:00
abstract：:Isolated death (ID) (i.e., dying alone without anyone noticing for several days) has been suggested to be related to social isolation, mental disorder, and alcohol and/or drug abuse. A major transfer of patients with a mental disorder and/or alcohol and/or drug abuse from institutionalized care to treatment as outpati...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2004-03-01 00:00:00
abstract：:Although the change in adenosine phosphate levels in muscles may contribute to the development of rigor mortis, the relationship between their levels and the onset and development of rigor mortis has not been well elucidated. In the current study, levels of the adenosine phosphates including adenosine triphosphate (AT...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2010.01450.x
更新日期：2010-09-01 00:00:00
abstract：:A fatality in a teenager from the recreational intranasal abuse of methylphenidate (Ritalin) is reported. The prescribed use of methylphenidate (Ritalin) in the treatment of attention deficit and/or hyperactivity disorder is widespread. The intranasal abuse of methylphenidate (Ritalin) among teenagers is becoming incr...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1999-01-01 00:00:00
abstract：:The hip bone is considered to be one of the most reliable indicators in sex determination. The aim of this study was to test the reliability of the DSP method for the hip bone proposed by Murail et al. (Bull Mem Soc Anthropol Paris, 17, 2005, 167) on a sample from a present-day population in France (52 males and 54 fe...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12817
更新日期：2015-09-01 00:00:00
